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Job DescriptionP06241
Confidence100.00%DateSat Jun 16 10:36:34 BST 2012
Rank248Aligned Residues245
% Identity24%Templatec2ojiA_
PDB info PDB header:transferaseChain: A: PDB Molecule:mitogen-activated protein kinase 1; PDBTitle: crystal structure of erk2 in complex with n-benzyl-4-(4-(3-2 chlorophenyl)-1h-pyrazol-3-yl)-1h-pyrrole-2-carboxamide
Resolution2.60 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


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Query Sequence  ESLQLIKRLGNGQFGEVWMGTWNGNTK. VAIKTLKP. . GTMSPESFLEEAQIMKKLKHDKLVQLYAVVSE. . . . . . EPIY
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Template Sequence  PRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVY
Template Known Secondary structure  SSTTTTTT

TTS


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SSTTT


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   21........30.........40.........50.........60.........70.........80.........90.........100
 
   340.........350.........360.........370.........380.........390.........400.........410.........
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Query Sequence  IVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNE
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Template Sequence  IVQDLMETDLYKLLK. . . . TQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDH
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   420.........430 .........440.........450.........460.........470.........480........
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Query Sequence  YTARQGAKFPI. . . KWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCP. . . . . . . .
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Template Sequence  DHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS. NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIIN
Template Known Secondary structure 
B

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   177..180.........190.........200.........210.........220. ........230.........240.........250.....
 
   489490.........500.........510........
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . QDCPISLHELMIHCWKKDPEERPTFEYLQS
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Template Sequence  LKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALA
Template Known Secondary structure  TS







TTS
T
SSTTTS

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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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