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Job DescriptionP06241
Confidence100.00%DateSat Jun 16 10:36:34 BST 2012
Rank5Aligned Residues431
% Identity65%Templatec2c0iA_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983
Resolution2.30 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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   86...90.........100.........110.........120.........130.........140.........150.........160.....
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Query Sequence  LFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLS
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Template Conservation     
          

    

   

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Template Sequence  IVVALYDYEAIHHEDLSFQKGDQMVVLEE. SGEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLA
Template Known Secondary structure  SS
B


SSSB

B
TT
.TTTTT

GGGTTSGGGSTTTT

TS
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   61........70.........80......... 90.........100.........110.........120.........130.........
 
   166...170.........180.........190.........200.........210.........220.........230.........240.....
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Query Sequence  FGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCRLVVP
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Template Sequence  PGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVP
Template Known Secondary structure  TT

TT

SSSTT
TTTB

STT
SSTTSSSTTSS
SS
SS


SB
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   140.........150.........160.........170.........180.........190.........200.........210.........
 
   246...250.........260.........270.........280.........290.........300.........310.........320.....
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Query Sequence  CHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDK
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Template Sequence  CMSSKPQ. . . . KPWEKDAWEIPRESLKLEKKLGAGQFGEVWMATYNKHTKVAVKTMKPGSMSVEAFLAEANVMKTLQHDK
Template Known Secondary structure 






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TT
SB

GGGTTTTT


SS
T


TT
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   220...... ...230.........240.........250.........260.........270.........280.........290.....
 
   326...330.........340.........350.........360.........370.........380.........390.........400.....
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Query Sequence  LVQLYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICK
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Template Sequence  LVKLHAVVTKEPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVSASLVCK
Template Known Secondary structure  B


SSS


TT
BSTTGGG

TT


S

SGGG
TT

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   296...300.........310.........320.........330.........340.........350.........360.........370.....
 
   406...410.........420.........430.........440.........450.........460.........470.........480.....
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Query Sequence  IADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRM
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Template Sequence  IADFGLAR. . . . . . . . . . . . . VIPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRM
Template Known Secondary structure 

TTGGG.............T

GGGS




TTT

SSTT

TT


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   376...380... ......390.........400.........410.........420.........430.........440..
 
   486...490.........500.........510.........520.........530....
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Query Sequence  PCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTATEPQYQPG
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Template Sequence  PRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQEEIP
Template Known Secondary structure 


TT

T
SSGGGS

TTTS
GGG




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   456...460.........470.........480.........490.........500....
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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