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Job DescriptionP06241
Confidence100.00%DateSat Jun 16 10:36:34 BST 2012
Rank1Aligned Residues451
% Identity77%Templatec1y57A_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
Resolution1.91 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   84.....90.........100.........110.........120.........130.........140.........150.........160...
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Query Sequence  VTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQL
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Template Conservation      

          

    

   
       

       
  
 

 
 
     
    

 
 
 
  

  
Template Sequence  VTTFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLL
Template Known Secondary structure  TTSS
B


SSSB

B
TT

S

SSSSTTT

GGGTTSGGGSTTS

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   83......90.........100.........110.........120.........130.........140.........150.........160..
 
   164.....170.........180.........190.........200.........210.........220.........230.........240...
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Query Sequence  LSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCRLV
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Template Conservation         
 



 
    
   


          
 
  
     
         
 

  

  
      
   
 
Template Sequence  LNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLT
Template Known Secondary structure  T
TT

TT

SSSTT
TTT
SSS
SSTTSSS

TTSSS


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   163......170.........180.........190.........200.........210.........220.........230.........240..
 
   244.....250.........260.........270.........280.........290.........300.........310.........320...
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Query Sequence  VPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKH
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Template Conservation       ...             

      
   

 
 

 
  
       



 
         
  
  

  
 
Template Sequence  TVCPT. . . SKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRH
Template Known Secondary structure 
B


...




SS



TTB

GGGTTTTT
TTSS



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   243.... ..250.........260.........270.........280.........290.........300.........310.........
 
   324.....330.........340.........350.........360.........370.........380.........390.........400...
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Query Sequence  DKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLI
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Template Conservation 



 
 
        

 

   


   
                  
    
  
     

 

   
 
      
Template Sequence  EKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLV
Template Known Secondary structure  TTB


SSS


TTS

TT
S

SGGG
GGG
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   320.........330.........340.........350.........360.........370.........380.........390.........
 
   404.....410.........420.........430.........440.........450.........460.........470.........480...
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Query Sequence  CKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGY
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Template Conservation   

 




                     


       
 








 
 

 
 
  
        
   
  
 
Template Sequence  CKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGY
Template Known Secondary structure 


TT


SS




TTTT
SGGGS




TTS

SSTT

TT
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   400.........410.........420.........430.........440.........450.........460.........470.........
 
   484.....490.........500.........510.........520.........530.......
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Query Sequence  RMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTATEPQYQPGENL
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Template Conservation 
   
      
  

  
   

  


   
   

         
      
Template Sequence  RMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
Template Known Secondary structure 




TT

T
SSGGGS

TT
TT



S

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   480.........490.........500.........510.........520.........530...
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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