|   |   |
381 | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
420 | . | . | . | . | . | . | . | . | . | 430 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  | . | . | . | . | . |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
| Query Sequence |   |
W | T | A | Q | G | F | L | S | P | L | A | A | A | V | G | G | V | A | S | Q | E | V | L | K | A | V | T | G | K | F | S | P | L | C | Q | W | L | Y | L | . |
. |
. |
. |
. |
E | A | A | D | I | V | E | S | L | G | K | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | C | E | E | F | L | P |
| Query Conservation |   |
|   |   |   |   |
|
|   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |
|
|   |
|
|   |
|   |   |   |
| . | . | . | . | . |
|
|   |
|   |
|
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |   | . |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
R | Y | V | K | I | A | R | Y | G | S | G | G | L | V | G | G | G | G | K | E | Q | Y | V | E | N | . |
L | V | L | W | E | N | I | I | K | T | A | Y | C | F | I | T | P | S | S | Y | T | A | A | L | E | T | A | N | I | P | E | K | D | F | S | N | C | F | R | F | L | K | E | N | F | F | I | I | P | G | E | Y | N | N |
| Template Known Secondary structure |   |
T | T |
|
|  |  |  |  | T | T |  |  |  |  | S | S | S | T | T |
|  |  |  |
|
| . |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S | S |
| B |
|  |  |  |  |  | T | T |
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |  |  |  | G | G | G | G |
|
| Template Predicted Secondary structure |   |
 |  |  |
|
|  |  |
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
7 | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | |
. | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . |
|   |
|   |   |
439 | 440 | . | . | . | . | . | . | . | . | . | 450 | |
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . |
| Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
R | G | D | R | Y | D | A | L | R | A | C | I | . |
. |
. |
. |
. |
. |
G | D | T | L | C | Q | K | L | Q | N | L | N | I | F | L | V | G | C | G | A | I | G | C | E | M | L | K | N | F | A | L | L | G | V | G | T | S | K | E | K | G | M | I | T | V | T | D | P | D | L | I | E | K | S | N | L | N | R | Q | F | L | F |
| Query Conservation |   |
  |   |   |
|
|
|   |   |   |   |
|   | . | . | . | . | . | . |
|   |   |   |   |   |
|
|   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|   |
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |
|   |
|   |
|   |
|   |
|
|
|
|   |
|
|
|
|
|
|
|
|
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|   |
|
|
|   |
|
|   |
|   |   |   |   |   |   |
|
|   |   |
|
|   | . | . | . | . | . | . |   |
|   |
|   |
|   |
|   |
|   |   |
|
|
|   |
|
|   |
|   |
| Template Sequence |   |
S | N | N | R | Y | S | R | N | F | L | H | Y | Q | S | Y | G | A | N | P | V | L | V | Q | D | K | L | K | N | A | K | V | V | I | L | G | C | G | G | I | G | N | H | V | S | V | I | L | A | T | S | G | I | G | . |
. |
. |
. |
. |
. |
E | I | I | L | I | D | N | D | Q | I | E | N | T | N | L | T | R | Q | V | L | F |
| Template Known Secondary structure |   |
|
|
| T | T |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S | . | . | . | . | . | . |  |  |  |  |  |
|
|
| B |
|
| S | G | G | G | G | T |
| T | T |
|
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
86 | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
. | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . |
|   |
|   |   |
513 | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | |
. | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . |
| Predicted Secondary structure |   |
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
| . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
R | P | H | H | I | Q | K | P | K | S | Y | T | A | A | D | A | T | L | K | I | N | S | Q | I | K | I | D | A | H | L | N | K | V | C | P | T | T | E | T | I | Y | N | D | E | F | Y | T | K | Q | D | V | I | I | T | A | L | D | N | . |
V | E | A | R | R | Y | V | D | S | R | C | L | A | N | L | R | P | L | L | D | S |
| Query Conservation |   |
|   |   |
|
|
|
|   |
|
|   |
|
|   |   |   |   |   |   |   |
|
|   |   |   |
|   |
|   |   |   |   |
|   |   |   |
|
|   |   |
|   |   |   |
|   |   |   |   |
|
|
|   |
|
|
|
|
| . |   |   |
|
|   |
|
|
|   |   |
|   |   |   |   |   |
|
|
|
|
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |
|
|
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|
|   |
|   |
|   |   |   |   |   |   |
|   |   |   | . | . | . | . |   |   |   |   |   |
|   |   |   |
|
|
|
|   |   |
|
|
|   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |
|
|   |
|   |   |
| Template Sequence |   |
S | E | D | D | V | G | K | N | K | T | E | V | I | K | R | E | L | L | K | R | N | S | E | I | S | V | S | E | I | A | L | N | I | N | D | Y | . |
. |
. |
. |
T | D | L | H | K | V | P | E | A | D | I | W | V | V | S | A | D | H | P | F | N | L | I | N | W | V | N | K | Y | C | V | R | A | N | Q | P | Y | I | N | A |
| Template Known Secondary structure |   |
| G | G | G | T | T | S | B |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T | S |  |  |  |  |  |
|
|
|
| S | S | G | . | . | . | . | G | G | G | G | G | S |
|
|
| S |  |  |  |  |
|
|
|
| S | T | T |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |
| Template Predicted Secondary structure |   |
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  | . | . | . | . |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
162 | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | |
|
|
|
. | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . |
|   |
|   |   |
592 | . | . | . | . | . | . | . | 600 | . | . | . | . | |
. | . | . | . | . | 610 | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
G | T | M | G | T | K | G | H | T | E | V | I | V | . |
P | H | L | T | E | S | Y | N | S |
| Query Conservation |   |
|
|   |
|   |
|
|   |
|
|
|
|
| . |
|   |   |
|
|   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |   |
|   |   |
|   |   |
|   |   |   |   |
|   |   |
|   |
|   |   |
|
| Template Sequence |   |
G | Y | V | N | D | I | A | V | F | G | P | L | Y | V | P | G | K | T | G | C | Y | E | C |
| Template Known Secondary structure |   |
 |  |  | T | T |  |  |  |  |  |  |  |  |
| T | T | T | S |
|
| T | T | S |
| Template Predicted Secondary structure |   |
 |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
238 | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 |
|   |