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Job DescriptionA0AVT1
Confidence100.00%DateTue Apr 3 14:58:27 BST 2012
Rank1Aligned Residues980
% Identity43%Templatec3cmmA_
PDB info PDB header:ligase/protein bindingChain: A: PDB Molecule:ubiquitin-activating enzyme e1 1; PDBTitle: crystal structure of the uba1-ubiquitin complex
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   38.40.........50.........60.........70.........80.........90.........100.........110.......
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Query Sequence  EIDDALYSRQRYVLGDTAMQKMAKSHVFLSGMGGLGLEIAKNLVLAGIKAVTIHDTEKCQAWDLGTNFFLSEDDVVNKRN
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Template Sequence  EIDESLYSRQLYVLGKEAMLKMQTSNVLILGLKGLGVEIAKNVVLAGVKSMTVFDPEPVQLADLSTQFFLTEKDI. . GQK
Template Known Secondary structure 


S
TT


S

S

SB

GGGGGT
TT

GGGT..TSB
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   13......20.........30.........40.........50.........60.........70.........80....... ..90
 
   118.120.........130.........140.........150.........160.. .......170.........180.........190......
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Query Sequence  RAEAVLKHIAELNPYVHVTSSSVPFNETTDLSFLDKYQCVVLTEM. KLPLQKKINDFCRSQCPPIKFISADVHGIWSRLF
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Template Sequence  RGDVTRAKLAELNAYVPVNVLDSLDDV. . . . TQLSQFQVVVATDTVSLEDKVKINEFCHSS. . GIRFISSETRGLFGNTF
Template Known Secondary structure  TTS
TTS






S....TTGGG
S
TTS
..T
TT
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   91........100.........110....... ..120.........130.........140....... ..150.........160....
 
   197..200.........210.........220.........230.........240.........250........ .260.........270.....
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Query Sequence  CDFGDEFEVLDTTGEEPKEIFISNITQANPGIVTCLENHPHKLETGQFLTFREINGMTGLNG. SIQQITVISPFSFSIGD
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Template Sequence  VDLGDEFTVLDPTGEEPRTGMVSDIEPD. . GTVTMLDDNRHGLEDGNFVRFSEVEGLDKLNDGTLFKVEVLGPFAFRIGS
Template Known Secondary structure 

S
SBSS





TT..
STT





TT


BTSGGGGSS


TT
S
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   165....170.........180.........190.. .......200.........210.........220.........230.........240..
 
   276...280.........290.........300.........310.........320.........330......... 340.........350....
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Query Sequence  TTELEPYLHGGIAVQVKTPKTVFFESLERQLKHPKCLIVDFSNPEAPLEIHTAMLALDQFQEKY. SRKPNVGCQQDSEEL
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Template Sequence  VKEYGEYKKGGIFTEVKVPRKISFKSLKQQLSNPEFVFSDFAKFDRAAQLHLGFQALHQFAVRHNGELPRTMNDEDANEL
Template Known Secondary structure 
TTT



B









S

B

S
GGGTTTT



TT
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   243......250.........260.........270.........280.........290.........300.........310.........320..
 
   355....360....... ..370.........380.........390.........400.........410.........420....... .
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Query Sequence  LKLATSISETLEE. . . . KPDVNADIVHWLSWTAQGFLSPLAAAVGGVASQEVLKAVTGKFSPLCQWLYLEAADIVES. . L
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Template Sequence  IKLVTDLSVQQPEVLGEGVDVNEDLIKELSYQARGDIPGVVAFFGGLVAQEVLKACSGKFTPLKQFMYFDSLESLPDPKN
Template Known Secondary structure 

TT



TTT



BS



S
GGGS

TTT
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   323......330.........340.........350.........360.........370.........380.........390.........400..
 
   429430.........440.........450.........460.........470.........480.........490.........500........
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Query Sequence  GKPECEEFLPRGDRYDALRACIGDTLCQKLQNLNIFLVGCGAIGCEMLKNFALLGVGTSKEKGMITVTDPDLIEKSNLNR
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Template Sequence  FPRNEKTTQPVNSRYDNQIAVFGLDFQKKIANSKVFLVGSGAIGCEMLKNWALLGLGSG. SDGYIVVTDNDSIEKSNLNR
Template Known Secondary structure  S

STTTTS

SSTT
T


STTT
S.TT



B

GGGTTT
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   403......410.........420.........430.........440.........450.........460. ........470.........480.
 
   509510.........520.........530...... ...540.........550.........560.........570.........580......
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Query Sequence  QFLFRPHHIQKPKSYTAADATLKINSQI. . KIDAHLNKVCPTTETIYNDEFYTKQDVIITALDNVEARRYVDSRCLANLR
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Template Sequence  QFLFRPKDVGKNKSEVAAEAVCAMNPDLKGKINAKIDKVGPETEEIFNDSFWESLDFVTNALDNVDARTYVDRRCVFYRK
Template Known Secondary structure 
TT

GGGTTSB
GGGTTT



SGGGTTTS

S

SST
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   482.......490.........500.........510.........520.........530.........540.........550.........560.
 
   587..590.........600.........610.........620.........630.........640.........650.........660......
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Query Sequence  PLLDSGTMGTKGHTEVIVPHLTESYNSHRDPPEEEIPFCTLKSFPAAIEHTIQWARDKFESSFSHKPSLFNKFWQTYSSA
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Template Sequence  PLLESGTLGTKGNTQVIIPRLTESYSSSRDPPEKSIPLCTLRSFPNKIDHTIAWAKSLFQGYFTDSAENVNMYLTQPNFV
Template Known Secondary structure 
TT
TTTB

GGGS








T


ST
TT
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   562.......570.........580.........590.........600.........610.........620.........630.........640.
 
   667..670.........680.........690.........700.........710.........720.........730.........740......
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Query Sequence  EEVLQKIQSGHSLEGCFQVIKLLSRRPRNWSQCVELARLKFEKYFNHKALQLLHCFPLDIRLKDGSLFWQSPKRPPSPIK
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Template Sequence  EQTLK. . . . . DVKGVLESISDSLSSKPHNFEDCIKWARLEFEKKFNHDIKQLLFNFPKDAKTSNGEPFWSGAKRAPTPLE
Template Known Secondary structure 
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S

SSTS
TT
B
STT
BSS
TT







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   642.... ...650.........660.........670.........680.........690.........700.........710......
 
   747..750.........760.........770....... ..780.........790.........800.........810.........820....
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Query Sequence  FDLNEPLHLSFLQNAAKLYATVYCIPFAEED. . LSADALLNILSEVKIQEFKPSNKVVQTDETARKPDHVPISSEDERNA
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Template Sequence  FDIYNNDHFHFVVAGASLRAYNYGIKSDDSNSKPNVDEYKSVIDHMIIPEFTPNANLKIQVNDDDPDPE. . . . . . . . . . .
Template Known Secondary structure 

TTST


SSTTSS

TT








SS



SSTTSS


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   720.........730.........740.........750.........760.........770.........780........
 
   825....830.........840.........850.........860.........870.........880.........890.........900....
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Query Sequence  IFQLEKAILSNEATKSDLQMAVLSFEKDDDHNGHIDFITAASNLRAKMYSIEPADRFKTKRIAGKIIPAIATTTATVSGL
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Template Sequence  . IDQLVSSLPDPSTLAGFKLEPVDFEKDDDTNHHIEFITACSNCRAQNYFIETADRQKTKFIAGRIIPAIATTTSLVTGL
Template Known Secondary structure  .
TTS

GGGGTT








TT
TTSSTT




TT




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   798.800.........810.........820.........830.........840.........850.........860.........870......
 
   905....910...... ...920.........930.........940.........950.........960.........970.........980...
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Query Sequence  VALEMIKVTGGY. PFEAYKNCFLNLAIPIVVFTETTEVRKTKIRNGISFTIWDRWTVHGKEDFTLLDFINAVKEKYGIEP
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Template Sequence  VNLELYKLIDNKTDIEQYKNGFVNLALPFFGFSEPIASPKGEYNNKKYDKIWDRFDIKG. . DIKLSDLIEHFEKDEGLEI
Template Known Secondary structure  TT


GGG

TTTT


B

TTTTT
S..

BTT

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   877..880.........890.........900.........910.........920.........930..... ....940.........950....
 
   984.....990.........1000. ........1010.........1020... ......1030.........1040.......
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Query Sequence  TMVVQGVKMLYVPVMPGH. . AKRLKLTMHKLVKPTTEKKYVD. . . . LTVSFAPDIDGDEDLPGPPVRYYF
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Template Conservation    
  
   

            
      
                 
     
     
  
 
    
Template Sequence  TMLSYGVSLLYASFFPPKKLKERLNLPITQLVKLVTKKDIPAHVSTMILEICADDKEGEDVEVPFITIHL
Template Known Secondary structure  TTTT

TTSBSSS


SS


TTS




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   955....960.........970.........980.........990.........1000.........1010.........1020....
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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