Return to main results Retrieve Phyre Job Id

Job DescriptionO00459
Confidence100.00%DateFri May 25 09:44:30 BST 2012
Rank9Aligned Residues194
% Identity30%Templatec3gqiB_
PDB info PDB header:transferase/transferase inhibitorChain: B: PDB Molecule:phospholipase c-gamma-1; PDBTitle: crystal structure of activated receptor tyrosine kinase in complex2 with substrates
Resolution2.50 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   327..330...... ...340.... .....350.........360.........370.........380...... ...390.
Predicted Secondary structure 









...........































....




Query SS confidence 









. . . . .







. . . . . .









































. . . .




Query Sequence  DAEWYWGDIS. . . . . REEVNEKL. . . . . . RDTPDGTFLVRDASSKIQGEYTLTLRKGGNNKLIKVFHRDGH. . . . YGFSE
Query Conservation    


 
 

.....

 


 
......    






 

    
 
 

           
    
 ....   
 
Alig confidence 









.....







......















.
























....




Template Conservation     



 

     
  

 

          

 



 
   . 
  



     
 
  
               
Template Sequence  SEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETF. VGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTD
Template Known Secondary structure 
STT

GGGSST

TT

SSS.TTS
SS


SSS
T
Template Predicted Secondary structure 


























.










Template SS confidence 















































































   547..550.........560.........570.........580.........590. ........600.........610.........620.....
 
   392.......400.........410.........420.........430.........440.........450.........460.........470.
Predicted Secondary structure 




































Query SS confidence 















































































Query Sequence  PLTFCSVVDLINHYRHESLAQYNAKLDTRLLYPVSKYQQDQIVKEDSVEAVGAQLKVYHQQYQDKSREYDQLYEEYTRTS
Query Conservation     
 

  

  

  

   
  
 


  
 

 
 
  
 
  

 
   

          
  
 
 
      
Alig confidence 

















..............................................................
Template Conservation     
 

 


  
    ..............................................................
Template Sequence  NLVFDSLYDLITHYQQVP. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  TSSS
..............................................................
Template Predicted Secondary structure 







..............................................................
Template SS confidence 















































































   626...630.........640...
 
   472.......480.........490.........500.........510.........520.........530.........540.........550.
Predicted Secondary structure 




Query SS confidence 















































































Query Sequence  QELQMKRTAIEAFNETIKIFEEQGQTQEKCSKEYLERFRREGNEKEMQRILLNSERLKSRIAEIHESRTKLEQQLRAQAS
Query Conservation   


     



 
 

 
  

   

   
     


    
   
    
 
   
 

      

 


    
Template Conservation  ................................................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ................................................................................
Template Predicted Secondary structure  ................................................................................
Template SS confidence 















































































  
 
   552.......560.........570.........580.........590.........600.........610.........620.........630.
Predicted Secondary structure 






























Query SS confidence 















































































Query Sequence  DNREIDKRMNSLKPDLMQLRKIRDQYLVWLTQKGARQKKINEWLGIKNETEDQYALMEDEDDLPHHEERTWYVGKINRTQ
Query Conservation      

 

 


 

 

 
  
     
  
   
  
 
 
           
 
     
   
  
 

 
 
 
Alig confidence  ..............................................

































Template Conservation  ..............................................
        
        
     



 
 
 
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . LRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQ
Template Known Secondary structure  ..............................................


SS






B


SSGGGGSSSSS

Template Predicted Secondary structure  ..............................................






















Template SS confidence 















































































   644.....650.........660.........670.......
 
   632.......640 .........650.........660.........670.........680.........690.........700.........710
Predicted Secondary structure 



.































Query SS confidence 








.





































































Query Sequence  AEEMLSGKR. DGTFLIRESSQRGCYACSVVVDGDTKHCVIYRTATGFGFAEPYNLYGSLKELVLHYQHASLVQHNDALTV
Query Conservation 




    .






 
   
 



      
 
  
     

 
        

  

 

   

  


 
  
Alig confidence 








.




































..




















.....




Template Conservation 

  
      
 

 
 
   
 




     
 
  
       ..      
 

  

  
   
.....
    
Template Sequence  AEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQEGQTV. . MLGNSEFDSLVDLISYYEKHP. . . . . LYRKM
Template Known Secondary structure  T

SSS
SSSSTTTT..TTSSTTS
.....SBTTB
Template Predicted Secondary structure 



















..





.....




Template SS confidence 















































































   678.680.........690.........700.........710.........720.... .....730.........740..... ....750
 
   711.....
Predicted Secondary structure 


Query SS confidence 





Query Sequence  TLAHPV
Query Conservation   
  

Alig confidence 





Template Conservation   
  

Template Sequence  KLRYPI
Template Known Secondary structure 



Template Predicted Secondary structure 



Template SS confidence 





   751.....
 
Download:Text version FASTA pairwise alignment 3D Model in PDB format

View in Jmol

Send structure to FirstGlance for more viewing options


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions