Job Description O00459 Confidence 100.00% Date Fri May 25 09:44:30 BST 2012 Rank 3 Aligned Residues 236 % Identity 100% Template c2y3aB_ PDB info PDB header:transferase Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit beta; PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941 Resolution 3.30 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		447	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	V	Y	H	Q	Q	Y	Q	D	K	S	R	E	Y	D	Q	L	Y	E	E	Y	T	R	T	S	Q	E	L	Q	M	K	R	T	A	I	E	A	F	N	E	T	I	K	I	F	E	E	Q	G	Q	T	Q	E	K	C	S	K	E	Y	L	E	R	F	R	R	E	G	N	E	K	E	M	Q	R	I	L	L	N	S	E
Query Conservation
Alig confidence																																																													.	.	.	.	.	.
Template Conservation																																																													.	.	.	.	.	.
Template Sequence		K	V	Y	H	Q	Q	Y	Q	D	K	S	R	E	Y	D	Q	L	Y	E	E	Y	T	R	T	S	Q	E	L	Q	M	K	R	T	A	I	E	A	F	N	E	T	I	K	I	F	E	E	Q	G	Q	T	Q	E	K	C	S	K	E	Y	.	.	.	.	.	.	L	G	N	E	K	E	M	Q	R	I	L	L	N	S	E
Template Known Secondary structure					S	S							T	T	T																																											T			.	.	.	.	.	.			T	T	T
Template Predicted Secondary structure																																																													.	.	.	.	.	.
Template SS confidence
		441	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.							500	.	.	.	.	.	.	.	.	.	510	.	.	.	.
		527	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	L	K	S	R	I	A	E	I	H	E	S	R	T	K	L	E	Q	Q	L	R	A	Q	A	S	D	N	R	E	I	D	K	R	M	N	S	L	K	P	D	L	M	Q	L	R	K	I	R	D	Q	Y	L	V	W	L	T	Q	K	G	A	R	Q	K	K	I	N	E	W	L	G	I	K	N	E	T	E	D	Q	Y	A
Query Conservation
Alig confidence																																																										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		R	L	K	S	R	I	A	E	I	H	E	S	R	T	K	L	E	Q	D	L	R	A	Q	A	S	D	N	R	E	I	D	K	R	M	N	S	L	K	P	D	L	M	Q	L	R	K	I	R	D	Q	Y	L	V	W	L	L	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure																																							T											T	T			S				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																																										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		521	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.
		607	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	M	E	D	E	D	D	L	P	H	H	E	E	R	T	W	Y	V	G	K	I	N	R	T	Q	A	E	E	M	L	S	G	K	R	D	G	T	F	L	I	R	E	S	S	Q	R	G	C	Y	A	C	S	V	V	V	D	G	D	T	K	H	C	V	I	Y	R	T	A	T	G	F	G	F	A	E	P	Y	N	L	Y
Query Conservation
Alig confidence		.	.	.	.	.	.	.	.
Template Conservation		.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	P	H	H	E	E	R	T	W	Y	V	G	K	I	N	R	T	Q	A	E	E	M	L	S	G	K	R	D	G	T	F	L	I	R	E	S	S	Q	R	G	C	Y	A	C	S	V	V	V	D	G	D	T	K	H	C	V	I	Y	R	T	A	T	G	F	G	F	A	E	P	Y	N	L	Y
Template Known Secondary structure		.	.	.	.	.	.	.	.	G	G	G	S	S	T	T	T	B			S											T	T	S		T	T	B			B				S	S	T	T									S	S	S										T	T				S	B	T	T	B
Template Predicted Secondary structure		.	.	.	.	.	.	.	.
Template SS confidence
										609	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680
		687	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720
Predicted Secondary structure
Query SS confidence
Query Sequence		G	S	L	K	E	L	V	L	H	Y	Q	H	A	S	L	V	Q	H	N	D	A	L	T	V	T	L	A	H	P	V	R	A	P	G
Query Conservation
Alig confidence
Template Conservation
Template Sequence		G	S	L	K	E	L	V	L	H	Y	Q	H	A	S	L	V	Q	H	N	D	A	L	T	V	T	L	A	H	P	V	R	A	P	G
Template Known Secondary structure		S	S							T	T	S	S	S		S	T	T	T		S	S						S	B		S
Template Predicted Secondary structure
Template SS confidence
		681	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions