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Job DescriptionO00459
Confidence100.00%DateFri May 25 09:44:30 BST 2012
Rank6Aligned Residues212
% Identity32%Templatec1a81E_
PDB info PDB header:complex (transferase/peptide)Chain: E: PDB Molecule:syk kinase; PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam
Resolution3.00 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   324.....330.........340.... .....350.........360.........370.........380 .........390.........400
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Query Sequence  SLQDAEWYWGDISREEVNEKL. . RDTPDGTFLVRDASSKIQGEYTLTLRKGGNNKLIKV. FHRDGHYGFSEPLTFCSVVD
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Template Sequence  SANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNY. LGGFALSVAHGRKAHHYTIERELNGTYAIAGGRTHASPAD
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GGG
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   910.........20.........30.........40....... ..50.........60.........70.........80.......
 
   401........410.........420.........430.........440.........450.........460.........470.........480
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Query Sequence  LINHYRHESLAQYNAKLDTRLLYPVSKYQQDQIVKEDSVEAVGAQLKVYHQQYQDKSREYDQLYEEYTRTSQELQMKRTA
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Template Sequence  LCHYHSQES. . . . . DGLVCLLKKPFNRPQGVQPKTPQLEKLIATT. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  TT

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   88.90...... ...100.........110.........120.......
 
   481........490.........500.........510.........520.........530.........540.........550.........560
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Query Sequence  IEAFNETIKIFEEQGQTQEKCSKEYLERFRREGNEKEMQRILLNSERLKSRIAEIHESRTKLEQQLRAQASDNREIDKRM
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   561........570.........580.........590.........600.........610.........620.........630...... ..
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Query Sequence  NSLKPDLMQLRKIRDQYLVWLTQKGARQKKINEWLGIKNETEDQYALMEDEDDLPHHEERTWYVGKINRTQAEEML. . SG
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . AHEKMPWFHGKISREESEQIVLIGS
Template Known Secondary structure  .......................................................SGGG
TT

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   162.......170.........180......
 
   639640.........650.........660.........670.........680.........690.........700.........710......
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Query Sequence  KRDGTFLIRESSQRGCYACSVVVDGDTKHCVIYRTATGFGFAEPYNLYGSLKELVLHYQHASLVQHNDALTVTLAHPV
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Template Sequence  KTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQLVEHYSYKA. . . . . DGLLRVLTVPC
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TT

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   187..190.........200.........210.........220.........230.........240........ .250.........
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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