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Job DescriptionP08631
Confidence100.00%DateThu Apr 26 09:51:20 BST 2012
Rank161Aligned Residues253
% Identity25%Templatec3mtfB_
PDB info PDB header:transferaseChain: B: PDB Molecule:activin receptor type-1; PDBTitle: crystal structure of the acvr1 kinase in complex with a 2-2 aminopyridine inhibitor
Resolution2.15 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   257..260.........270.........280.........290.........300.........310.........320.... .....330.
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Query Sequence  IPRESLKLEKKLGAGQFGEVWMATYNKHTKVAVKTMKPGSMSVEAFLAEANVMKTLQHDKLVKLHAVV. . . . . TKEPIYI
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Template Sequence  TVARDITLLECVGKGRYGEVWRGSW. QGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWL
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   203......210.........220....... ..230.........240.........250.........260.........270.........280.
 
   332.......340.........350.........360.........370....... ..380.........390.........400...
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Query Sequence  ITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNY. . . . . . . . IHRDLRAANILVSASLVCKIADFGLA
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Template Sequence  ITHYHEMGSLYDYLQLTT. . . LDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLA
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B

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S
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STT
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S

SGGG
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TT
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   282.......290......... 300.........310.........320.........330.........340.........350........
 
   404... ..410.........420.........430... ......440.........450.........460...
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Query Sequence  RVIE. . . DNEYTAREGAKFPIKWTAPEAINFGS. . . . . . FTIKSDVWSFGILLMEIVTYGRIPYPGMSN. . . . . . . . . . .
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Template Sequence  VMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVAR. RMVSNGIVEDYKPPFYDVVPN
Template Known Secondary structure  TTTT








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   359360.........370.........380.........390.........400.........410...... ...420.........430.......
 
   464.....470.........480. ........490.........500.........510....
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Query Sequence  . . . . PEVIRALERGYRMPRPEN. . . . . . CPEELYNIMMRCWKNRPEERPTFEYIQSVLDDF
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Template Sequence  DPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKI
Template Known Secondary structure  S

TTS






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   438.440.........450.........460.........470.........480.........490........
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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