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Job DescriptionP08631
Confidence100.00%DateThu Apr 26 09:51:20 BST 2012
Rank39Aligned Residues256
% Identity35%Templatec3lxkA_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase jak3; PDBTitle: structural and thermodynamic characterization of the tyk2 and jak32 kinase domains in complex with cp-690550 and cmp-6
Resolution2.00 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   257..260.........270.........280. ........290...... ...300.........310.........320.... ...
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Query Sequence  IPRESLKLEKKLGAGQFGEVWMATY. . . . . NKHTKVAVKTMKPGS. MSVEAFLAEANVMKTLQHDKLVKLHAVV. . . TKE
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Template Sequence  FEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQ
Template Known Secondary structure 

GGGTT
TTSSS
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T


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   817..820.........830.........840.........850.........860.........870.........880.........890......
 
   328.330.........340.........350.........360.........370.........380.........390.........400.......
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Query Sequence  PIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARVIE
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Template Sequence  SLRLVMEYLPSGCLRDFLQRH. RARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLP
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TT
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   897..900.........910....... ..920.........930.........940.........950.........960.........970.....
 
   408.410.........420.........430.........440.........450.........460 .........470.....
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Query Sequence  . . DNEYTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPG. . . . . . . . . . MSNPEVIRALERGYR
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Template Sequence  LDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFT. YCDKSCSPSAEFLRMMVPALSRLLELLEEGQR
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   976...980.........990.........1000.........1010.........1020.. .......1030.........1040.........1050....
 
   476...480.........490.........500.........510....
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Query Sequence  MPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDF
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Template Sequence  LPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDML
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TT

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   1060.........1070.........1080.........1090........
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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