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Job DescriptionP08631
Confidence100.00%DateThu Apr 26 09:51:20 BST 2012
Rank173Aligned Residues241
% Identity24%Templatec3kvwA_
PDB info PDB header:transferaseChain: A: PDB Molecule:dual specificity tyrosine-phosphorylation-regulated kinase PDBTitle: crystal structure of dual-specificity tyrosine phosphorylation2 regulated kinase 2 (dyrk2) in complex with an indirubin ligand
Resolution2.28 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   262.......270.........280...... ...290.........300.........310.... .....320.... .....330...
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Query Sequence  LKLEKKLGAGQFGEVWMATYNKHTK. VAVKTMKPGSMSVEAFLAEANVMKTLQH. . . . . . DKLVKLHAVV. TKEPIYIIT
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Template Sequence  YEVLKVIGKGSFGQVVKAYDHKVHQHVALKMVRNEKRFHRQAAEEIRILEHLRKQDKDNTMNVIHMLENFTFRNHICMTF
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   149150.........160.........170.........180.........190.........200.........210.........220........
 
   334.....340.........350.........360.........370.........380.........390... ......400.........410.
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Query Sequence  EFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVSASL. . VCKIADFGLARVIEDNEY
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Template Sequence  ELL. SMNLYELIKKNKFQGFSLPLVRKFAHSILQCLDALHKNRIIHCDLKPENILLKQQGRSGIKVIDFGSSCYEHQRVY
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   229230. ........240.........250.........260.........270.........280.........290.........300.......
 
   412.......420.........430.........440.........450.........460.........470.......
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Query Sequence  TAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMP. . . . . . . . . . . . . .
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Template Sequence  TIQSRF. . . . . YRAPEVILGARYGMPIDMWSLGCILAELLT. GYPLLPGEDEGDQLACMIELLGMPSQKLLDASKRAKNF
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   308.310... ......320.........330.........340... ......350.........360.........370.........380.
 
   478.480.........490.........500.........
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . RPENCPEELYNIMMRCWKNRPEERPTFEYIQS
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Template Sequence  VSKGYPRYCTVTTLSDVVLNGGRSRRGKLRGPPESREWGNALKGCDDPLFLDFLKQCLEWDPAVRMTPGQALR
Template Known Secondary structure  B



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   383......390.........400.........410.........420.........430.........440.........450.....
 
Download:Text version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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