Return to main results Retrieve Phyre Job Id

Job DescriptionP08631
Confidence100.00%DateThu Apr 26 09:51:20 BST 2012
Rank93Aligned Residues242
% Identity38%Templatec3k54A_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: structures of human bruton's tyrosine kinase in active and inactive2 conformations suggests a mechanism of activation for tec family3 kinases.
Resolution1.94 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   252.......260.........270.........280.........290.........300.........310.........320.... .....330
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Query Sequence  KDAWEIPRESLKLEKKLGAGQFGEVWMATYNKHTKVAVKTMKPGSMSVEAFLAEANVMKTLQHDKLVKLHAVV. TKEPIY
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Template Sequence  YGSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIK. . . . . . . EFIEEAKVMMNLSHEKLVQLYGVCTKQRPIF
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GGGB

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TTT

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TT


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   392.......400.........410.........420.........430... ......440.........450.........460....
 
   331........340.........350.........360.........370.........380.........390.........400.........410
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Query Sequence  IITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNE
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Template Sequence  IITEYMANGCLLNYLREMRHR. FQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGFP. . . . . . .
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GGG
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   472.......480.........490.. .......500.........510.........520.........530.........540...
 
   411........420.........430.........440.........450.........460.........470.........480.........490
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Query Sequence  YTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPENCPEELYNIM
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Template Sequence  . . . . . . . . . . VRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIM
Template Known Secondary structure  ..........GGG





TTS

TTTTS
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   561........570.........580.........590.........600.........610.........620.........630
 
   491........500.........510........
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Query Sequence  MRCWKNRPEERPTFEYIQSVLDDFYTAT
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Template Sequence  YSCWHEKADERPTFKILLSNILDVMDEE
Template Known Secondary structure  TT
SSGGGS


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   631........640.........650........
 
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No model constructed - rank, confidence too low




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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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