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Job DescriptionP08631
Confidence100.00%DateThu Apr 26 09:51:20 BST 2012
Rank44Aligned Residues257
% Identity35%Templatec3eygA_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes
Resolution1.90 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   253......260.........270.........280.. .......290.........300.........310.........320.......
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Query Sequence  DAWEIPRESLKLEKKLGAGQFGEVWMATYN. . . . . KHTKVAVKTMKPGSMSVEAFLAEANVMKTLQHDKLVKLHAVVTKE
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Template Sequence  DPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTGEQVAVKSLK. . . PHIADLKKEIEILRNLYHENIVKYKGICTEN
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   866...870.........880.........890.........900.........910. ........920.........930.........940..
 
   328.330.........340.........350.........360.........370.........380.........390.........400.......
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Query Sequence  PIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARVIE
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Template Sequence  GIKLIMEFLPSGSLKEYLPKN. KNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGDFGLTKAIE
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TT
BTGGG.TTT

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   951........960.........970. ........980.........990.........1000.........1010.........1020.........
 
   408.410.........420.........430.........440.........450........ .460.........470..
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Query Sequence  DNEYTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPY. . . . . . . . . . . . . . . PGMSNPEVIRALER
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Template Sequence  TDKETVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLT. YCDSDSSPMALFLKMIGPTHGQMTVTRLVNTLKE
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   1030.........1040.........1050.........1060.........1070.... .....1080.........1090.........1100........
 
   473......480.........490.........500.........510....
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Query Sequence  GYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDF
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Template Sequence  GKRLPCPPNCPDEVYQLMRKCWEFQPSNRTSFQNLIEGFEAL
Template Known Secondary structure  T





TT

T

SSGGGS

TT
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   1111........1120.........1130.........1140.........1150..
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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