Job Description P08631 Confidence 100.00% Date Thu Apr 26 09:51:20 BST 2012 Rank 56 Aligned Residues 250 % Identity 35% Template c3d4qA_ PDB info PDB header:transferase Chain: A: PDB Molecule:b-raf proto-oncogene serine/threonine-protein kinase; PDBTitle: pyrazole-based inhibitors of b-raf kinase Resolution 2.80 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		253	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300				.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																																		.	.	.
Query SS confidence																																																		.	.	.
Query Sequence		D	A	W	E	I	P	R	E	S	L	K	L	E	K	K	L	G	A	G	Q	F	G	E	V	W	M	A	T	Y	N	K	H	T	K	V	A	V	K	T	M	K	P	G	S	M	S	V	E	.	.	.	A	F	L	A	E	A	N	V	M	K	T	L	Q	H	D	K	L	V	K	L	H	A	V	V	T	K	E	P	I
Query Conservation																																																		.	.	.
Alig confidence																																	.	.																.	.	.
Template Conservation																																	.	.
Template Sequence		D	D	W	E	I	P	D	G	Q	I	T	V	G	Q	R	I	G	S	G	S	F	G	T	V	Y	K	G	K	W	H	G	.	.	D	V	A	V	K	M	L	N	V	T	A	P	T	P	Q	Q	L	Q	A	F	K	N	E	V	G	V	L	R	K	T	R	H	V	N	I	L	L	F	M	G	Y	S	T	K	P	Q	L
Template Known Secondary structure					B			T	T												T	T								S	S	S	.	.									S	S	S																	T	T				T	T	B									S	S	S
Template Predicted Secondary structure																																	.	.
Template SS confidence
		448	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.			.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.
		330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	I	I	T	E	F	M	A	K	G	S	L	L	D	F	L	K	S	D	E	G	S	K	Q	P	L	P	K	L	I	D	F	S	A	Q	I	A	E	G	M	A	F	I	E	Q	R	N	Y	I	H	R	D	L	R	A	A	N	I	L	V	S	A	S	L	V	C	K	I	A	D	F	G	L	A	R	V	I	E	D	N
Query Conservation
Alig confidence																								.																																																							.	.	.
Template Conservation																								.																																																							.	.	.
Template Sequence		A	I	V	T	Q	W	C	E	G	S	S	L	Y	H	H	L	H	I	I	E	T	K	.	F	E	M	I	K	L	I	D	I	A	R	Q	T	A	Q	G	M	D	Y	L	H	A	K	S	I	I	H	R	D	L	K	S	N	N	I	F	L	H	E	D	L	T	V	K	I	G	D	F	G	L	A	T	V	L	.	.	.
Template Known Secondary structure									S	S		B							T	S				.																							T	T		B		S			S	G	G	G					T	T	T								T	T		B			.	.	.
Template Predicted Secondary structure																								.																																																							.	.	.
Template SS confidence
		526	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.		.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.
		410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.				.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.		.	.	.	.	470	.	.	.	.	.	.	.					.	.	480	.
Predicted Secondary structure																										.	.	.																																	.													.	.	.	.
Query SS confidence																										.	.	.																																	.													.	.	.	.
Query Sequence		E	Y	T	A	R	E	G	A	K	F	P	I	K	W	T	A	P	E	A	I	N	F	G	S	.	.	.	F	T	I	K	S	D	V	W	S	F	G	I	L	L	M	E	I	V	T	Y	G	R	I	P	Y	P	G	M	S	N	P	E	.	V	I	R	A	L	E	R	G	Y	R	M	P	.	.	.	.	R	P	E	N
Query Conservation																										.	.	.																																	.													.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.																	.	.	.																				.													.													.	.	.	.
Template Conservation		.	.	.	.	.	.	.	.																																							.
Template Sequence		.	.	.	.	.	.	.	.	S	G	S	I	L	W	M	A	P	E	V	I	R	M	Q	D	K	N	P	Y	S	F	Q	S	D	V	Y	A	F	G	I	V	L	Y	E	L	M	T	.	G	Q	L	P	Y	S	N	I	N	N	R	D	Q	I	I	F	M	V	G	R	G	Y	L	S	P	D	L	S	K	V	R	S	N
Template Known Secondary structure		.	.	.	.	.	.	.	.					T	T							T	T		S	S				S																		.	S	S		T	T	T	T														T	S					G	G	G	S		T	T
Template Predicted Secondary structure		.	.	.	.	.	.	.	.																																							.
Template SS confidence
										614	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.		.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.
		482	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		C	P	E	E	L	Y	N	I	M	M	R	C	W	K	N	R	P	E	E	R	P	T	F	E	Y	I	Q	S	V	L	D	D	F	Y	T	A
Query Conservation
Alig confidence
Template Conservation
Template Sequence		C	P	K	A	M	K	R	L	M	A	E	C	L	K	K	K	R	D	E	R	P	L	F	P	Q	I	L	A	S	I	E	L	L	A	R	S
Template Known Secondary structure		S												T		S	S	G	G	G	S																T
Template Predicted Secondary structure
Template SS confidence
		685	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions