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Job DescriptionP08631
Confidence100.00%DateThu Apr 26 09:51:20 BST 2012
Rank196Aligned Residues255
% Identity32%Templatec3c1xA_
PDB info PDB header:transferaseChain: A: PDB Molecule:hepatocyte growth factor receptor; PDBTitle: crystal structure of the tyrosine kinase domain of the2 hepatocyte growth factor receptor c-met in complex with a3 pyrrolotriazine based inhibitor
Resolution2.17 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


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Query Sequence  DAWEIPRES. . LKLEKKLGAGQFGEVWMATYNKHT. . . . KVAVKTMKPGSMS. . VEAFLAEANVMKTLQHDKLVKLHAVV
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Template Sequence  QHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGIC
Template Known Secondary structure  TTTB

STT

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   1067..1070.........1080.........1090.........1100.........1110.........1120.........1130.........1140......
 
   325.. ..330.........340.........350.........360.........370.........380.........390.........400...
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Query Sequence  TKE. PIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLA
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Template Sequence  LRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKFLASKKFVHRDLAARNCMLDEKFTVKVADF. . .
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   1147..1150.........1160.........1170.........1180.........1190.........1200.........1210.........1220...
 
   404.....410.........420.........430.........440.........450.........460.........470.........480...
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Query Sequence  RVIEDNEYTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPENCP
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Template Sequence  . . . . . . . . . . . . . . . LPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCP
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   1245....1250.........1260.........1270.........1280.........1290.........1300.........
 
   484.....490.........500.........510.........520.....
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Query Sequence  EELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQYQQQ
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Template Sequence  DPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVH
Template Known Secondary structure  T
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   1310.........1320.........1330.........1340.........1350.
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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