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Job DescriptionP08631
Confidence100.00%DateThu Apr 26 09:51:20 BST 2012
Rank192Aligned Residues266
% Identity33%Templatec2xbaA_
PDB info PDB header:transferaseChain: A: PDB Molecule:alk tyrosine kinase receptor; PDBTitle: structure of human anaplastic lymphoma kinase in complex2 with pha-e429
Resolution1.95 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


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Query Sequence  AWEIPRESLKLEKKLGAGQF. . . . GEVWMATYNKHTKVAVKTM. . KPGSMSVEAFLAEANVMKTLQHDKLVKLHAVV. TK
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Template Sequence  CFAGKTSSISDLKEVPRKNITLIRGLVYEGQVS. PLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQS
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   1097..1100.........1110.........1120......... 1130.........1140.........1150.........1160.........1170.....
 
   327..330.........340....... ..350.........360.........370.........380.........390.........400.
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Query Sequence  EPIYIITEFMAKGSLLDFLKS. . . . . DEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFG
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Template Sequence  LPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIG
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   402.......410.........420.........430.........440.........450.........460.........470.........480.
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Query Sequence  LARVIEDNEYTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPEN
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Template Sequence  DFGMARDIYA. . . . . . MLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKN
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   1270......... 1280.........1290.........1300.........1310.........1320.........1330.........1340...
 
   482.......490.........500.........510.........520......
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Query Sequence  CPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQYQQQP
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Template Sequence  CPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALP
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   1354.....1360.........1370.........1380.........1390........
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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