|   |   |
384 | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 450 | . | . |
| Predicted Secondary structure |   |
 |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
| Query Sequence |   |
I | C | R | T | D | I | M | M | K | H | K | L | G | G | G | Q | Y | G | E | V | Y | E | A | V | W | K | R | Y | G | N | T | V | A | V | K | T | L | K | E | D | T | M | A | L | K | D | F | L | E | E | A | A | I | M | K | E | M | K | H | P | N | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | Q | L | I | G | V | C |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |
|   |
|
| . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |
|
|   |
|   |   |   |
|
|   |
|   |
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
Y | K | D | A | R | Y | I | L | V | R | K | L | G | W | G | H | F | S | T | V | W | L | A | K | D | M | V | N | N | T | H | V | A | M | K | I | V | R | G | D | K | V | Y | T | E | A | A | E | D | E | I | K | L | L | Q | R | V | N | D | A | D | N | T | K | E | D | S | M | G | A | N | H | I | L | K | L | L | D | H | F |
| Template Known Secondary structure |   |
 | T | T | T | T |  |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |  |  |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
| S |  |  |  |  |  |  |  | T | T | B |
|
|
|
|  |  |  |
| Template Predicted Secondary structure |   |
 |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
153 | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . |
|   |
|   |   |
453 | . | . | |
|
|
|
. | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | |
|
|
|
|
|
. |
| Predicted Secondary structure |   |
 |  |
| . | . | . | . |
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
| . | . | . | . | . | . |
|
| Query SS confidence |   |
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
| Query Sequence |   |
T | R | E | . |
. |
. |
. |
P | P | F | Y | I | I | T | E | F | M | S | H | G | N | L | L | D | F | L | R | S | A | G | R | E | T | L | D | A | V | A | L | L | Y | M | A | T | Q | I | A | S | G | M | S | Y | L | E | S | R | N | Y | I | H | R | D | L | A | A | R | N | C | L | V | G | D | N | . |
. |
. |
. |
. |
. |
K |
| Query Conservation |   |
  |   |   | . | . | . | . |   |   |   |   |   |
|   |
|   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |
|
|
|   |   |   |   |
|
|
|
|
|
|   |   |
|   |
|   |   |   |   | . | . | . | . | . | . |   |
| Alig confidence |   |
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
N | H | K | G | P | N | G | V | H | V | V | M | V | F | E | V | L | G | E | N | L | L | A | L | I | K | K | Y | E | H | R | G | I | P | L | I | Y | V | K | Q | I | S | K | Q | L | L | L | G | L | D | Y | M | H | R | R | C | G | I | I | H | T | D | I | K | P | E | N | V | L | M | E | I | V | D | S | P | E | N | L | I |
| Template Known Secondary structure |   |
 |  |  |  | T | T |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  | T | T | T | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |
| S |
|
| S | G | G | G |  |  |  |  |  |  |  | T | T | T | T |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
233 | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . |
|   |
|   |   |
523 | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . |
| Predicted Secondary structure |   |
|  |  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
L | V | K | V | A | D | F | G | L | A | R | L | M | R | D | D | T | Y | T | A | H | A | G | A | K | F | P | I | K | W | T | A | P | E | G | L | A | Y | N | K | F | S | T | K | S | D | V | W | A | F | G | V | L | L | W | E | I | A | T | Y | G | M | S | P | Y | P | A | I | D | L | T | D | V | Y | H | K | L | D | K | G |
| Query Conservation |   |
  |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |
|   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |   |   |   |   |   |   |   | . |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
| Template Sequence |   |
Q | I | K | I | A | D | L | G | N | A | C | W | Y | D | E | H | Y | T | N | . |
. |
. |
. |
S | I | Q | T | R | E | Y | R | S | P | E | V | L | L | G | A | P | W | G | C | G | A | D | I | W | S | T | A | C | L | I | F | E | L | I | T | . |
G | D | F | L | F | K | D | D | D | H | I | A | Q | I | I | E | L | L | G | E |
| Template Known Secondary structure |   |
 |  |  |  |
|
|
| T | T |
|  |  | T | T | B |
|
|
| S | . | . | . | . |
|
| S |
| G | G | G |
|
|  |  |  |  |  | T |
|
|
|
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| S |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
| . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
545 | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | |
|
|
|
. | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | |
600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . |
|   |
|   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
603 | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Y | R | M | E | R | P | P | G | C | P | P | E | V | Y | D | L | M | R | Q | C | W | Q | W | D | A | T | D | R | P | T | F | K | S | I | H | H | A | L | E | H | M | F | Q | E |
| Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
| Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|   |   |   |
|   |   |
|
|   |   |
|   |
|
|   |
|
| . | . | . |
|   |
|
|
|   |   |
| Template Sequence |   |
L | P | S | Y | L | L | R | N | G | K | Y | T | R | T | F | F | N | S | L | L | R | N | I | S | K | L | K | F | W | P | L | E | D | V | L | T | E | K | Y | K | F | S | K | D | E | A | K | E | I | S | D | F | L | S | P | M | L | Q | L | D | P | R | K | R | A | D | A | G | G | L | . |
. |
. |
V | N | H | P | W | L | K |
| Template Known Secondary structure |   |
|
|  |  |  |  |  |  |
| T | T |  |  |  |  | B |
|
|
| B | S | S |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  | T | T |
|
|
|  |  |  |  |  |  |  |  |  |  |  | G | G | G | G |
| S | S | T | T | T |
| B |
|  |  |  |  | . | . | . |  | T |
| G | G | G | T |
| Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  | . | . | . |  |
|
|  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
629 | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | |
|
|
. | 700 | . | . | . | . | . |
|   |
|   |   |
647 | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
S | S | I | T | E | A | V | E | K | Q | L | N | A | N | A | T | S | A | S | S | S | A | P | S | T | S | G | V | A | T |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
| Template Sequence |   |
D | T | L | G | M | E | E | I | R | V | P | D | R | E | L | Y | G | S | G | S | D | I | P | G | W | F | E | E | V | R |
| Template Known Secondary structure |   |
T |
| T | T |
| T | T |
|
|
| T | T | S |
| T | T |
| B | S | T | T | S | T | T | S | S | S |
|
|
|
| Template Predicted Secondary structure |   |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
708 | . | 710 | . | . | . | . | . | . | . | . | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . |
|   |