Job Description A8JNU2 Confidence 100.00% Date Tue Jan 22 11:54:53 GMT 2013 Rank 57 Aligned Residues 246 % Identity 26% Template c3vw6B_ PDB info PDB header:transferase/transferase inhibitor Chain: B: PDB Molecule:mitogen-activated protein kinase kinase kinase 5; PDBTitle: crystal structure of human apoptosis signal-regulating kinase 1 (ask1)2 with imidazopyridine inhibitor Resolution 2.40 Å

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		381	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460
Predicted Secondary structure
Query SS confidence
Query Sequence		E	W	E	I	C	R	T	D	I	M	M	K	H	K	L	G	G	G	Q	Y	G	E	V	Y	E	A	V	W	K	R	Y	G	N	T	V	A	V	K	T	L	K	E	D	T	M	A	L	K	D	F	L	E	E	A	A	I	M	K	E	M	K	H	P	N	L	V	Q	L	I	G	V	C	T	R	E	P	P	F	Y	I
Query Conservation
Alig confidence																																												.	.	.	.	.
Template Conservation																																												.	.	.	.	.
Template Sequence		E	Y	D	Y	E	Y	D	E	N	G	D	R	V	V	L	G	K	G	T	Y	G	I	V	Y	A	G	R	D	L	S	N	Q	V	R	I	A	I	K	E	I	P	E	.	.	.	.	.	Q	P	L	H	E	E	I	A	L	H	K	H	L	K	H	K	N	I	V	Q	Y	L	G	S	F	S	E	N	G	F	I	K	I
Template Known Secondary structure							B		T	T	S	S	B							S	S	S								T	T	T												.	.	.	.	.											T	T				T	T	B										T	T
Template Predicted Secondary structure																																												.	.	.	.	.
Template SS confidence
		672	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.						.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.
		461	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.		.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.
Predicted Secondary structure																						.																																							.
Query SS confidence																						.																																							.
Query Sequence		I	T	E	F	M	S	H	G	N	L	L	D	F	L	R	S	A	G	R	E	.	T	L	D	A	V	A	L	L	Y	M	A	T	Q	I	A	S	G	M	S	Y	L	E	S	R	N	Y	I	H	R	D	L	A	A	R	N	C	L	V	.	G	D	N	K	L	V	K	V	A	D	F	G	L	A	R	L	M	R	D	D
Query Conservation																						.																																							.
Alig confidence																						.																																							.																			.	.
Template Conservation																																																																																.	.
Template Sequence		F	M	E	Q	V	P	G	G	S	L	S	A	L	L	R	S	K	W	G	P	L	K	D	N	E	Q	T	I	G	F	Y	T	K	Q	I	L	E	G	L	K	Y	L	H	D	N	Q	I	V	H	R	D	I	K	G	D	N	V	L	I	N	T	Y	S	G	V	L	K	I	S	D	F	G	T	S	K	R	L	T	.	.
Template Known Secondary structure							T	T		B								T	T				T	T																						T	T				S			S	G	G	G					T	T	T									S	S						.	.
Template Predicted Secondary structure																																																																																.	.
Template SS confidence
		753	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830
		539	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.			.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.			.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.
Predicted Secondary structure																										.	.																														.	.
Query SS confidence																										.	.																														.	.
Query Sequence		T	Y	T	A	H	A	G	A	K	F	P	I	K	W	T	A	P	E	G	L	A	Y	N	K	.	.	F	S	T	K	S	D	V	W	A	F	G	V	L	L	W	E	I	A	T	Y	G	M	S	P	Y	P	A	I	D	.	.	L	T	D	V	Y	H	K	L	D	K	G	Y	R	M	E	R	P	P	G	C	P	P	E
Query Conservation																										.	.																														.	.
Alig confidence		.	.	.	.	.	.	.	.	.																.	.																				.										.	.
Template Conservation		.	.	.	.	.	.	.	.	.																																					.
Template Sequence		.	.	.	.	.	.	.	.	.	G	T	L	Q	Y	M	A	P	E	I	I	D	K	G	P	R	G	Y	G	K	A	A	D	I	W	S	L	G	C	T	I	I	E	M	A	T	.	G	K	P	P	F	Y	E	L	G	E	P	Q	A	A	M	F	K	V	G	M	F	K	V	H	P	E	I	P	E	S	M	S	A	E
Template Known Secondary structure		.	.	.	.	.	.	.	.	.			G	G	G										G	G	G		S																		.	S	S		T	T	G	G	G		S												T							T	T	S
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.																																					.
Template SS confidence
											841	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.		.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910
		615	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	Y	D	L	M	R	Q	C	W	Q	W	D	A	T	D	R	P	T	F	K	S	I	H	H	A	L	E	H	M	F	Q	E
Query Conservation
Alig confidence																								.	.	.
Template Conservation																								.	.	.
Template Sequence		A	K	A	F	I	L	K	C	F	E	P	D	P	D	K	R	A	C	A	N	D	L	.	.	.	L	V	D	E	F	L	K
Template Known Secondary structure										T		S		T	T	T	S							.	.	.		T	S	G	G	G
Template Predicted Secondary structure																								.	.	.
Template SS confidence
		911	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.				.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions