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Job DescriptionA8JNU2
Confidence100.00%DateTue Jan 22 11:54:53 GMT 2013
Rank102Aligned Residues257
% Identity44%Templatec3v5qB_
PDB info PDB header:transferase/transferase inhibitorChain: B: PDB Molecule:nt-3 growth factor receptor; PDBTitle: discovery of a selective trk inhibitor with efficacy in rodent cancer2 tumor models
Resolution2.20 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   382.......390.........400 .........410.........420 .........430.........440.........450.........
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Query Sequence  WEICRTDIMMKHKLGGGQY. GEVYEAVWKRYGNTVAVKTL. KEDTMALKDFLEEAAIMKEMKHPNLVQLIGVCTREPPFY
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Template Sequence  QHIKRRDIVLKRELGFKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDP. . LI
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GGG


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   531........540.........550.........560.........570.........580.........590.........600...... ..
 
   460.........470.........480.........490.........500.........510.........520.........530.........
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Query Sequence  IITEFMSHGNLLDFLRSAGRETLDAVALLYMATQIASGMSYLESRNYIHRDLAARNCLVGDNKLVKVADFGLARLMRDDT
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Template Sequence  MVFEYMKHGDLNKFLRAHGPE. LGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMDV. . . . . Y
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TTTT


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SGGG
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   615....620.........630..... ....640.........650.........660.........670.........680....... .
 
   540.........550.........560.........570.........580.........590.........600.........610.........
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Query Sequence  YTAHAGAKFPIKWTAPEGLAYNKFSTKSDVWAFGVLLWEIATYGMSPYPAIDLTDVYHKLDKGYRMERPPGCPPEVYDLM
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Template Sequence  STDYYRTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYDVM
Template Known Secondary structure  GGG
B


B
GGG





TTTS

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TT

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   706...710.........720.........730.........740.........750.........760.........770.........780.....
 
   620.........630.........640......
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Query Sequence  RQCWQWDATDRPTFKSIHHALEHMFQE
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Template Sequence  LGCWQREPQQRLNIKEIYKILHALGKA
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T
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   804.....810.........820.........830
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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