|   |   |
383 | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | |
|
|
|
430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
E | I | C | R | T | D | I | M | M | K | H | K | L | G | G | G | Q | Y | G | E | V | Y | E | A | V | W | K | R | Y | G | N | T | V | A | V | K | T | L | K | E | D | T | M | A | L | K | D | . |
. |
. |
. |
F | L | E | E | A | A | I | M | K | E | M | K | H | P | N | L | V | Q | L | I | G | V | C | T | R | E | P | P | F |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |
|   |   |   |   |   |   |
|   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |
|   |
|   |   |   |
|
|   |
|   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
Q | L | H | R | E | D | F | E | I | I | K | V | I | G | R | G | A | F | G | E | V | A | V | V | K | M | K | N | T | E | R | I | Y | A | M | K | I | L | N | K | W | E | M | L | K | R | A | E | T | A | C | F | R | E | E | R | D | V | L | V | N | G | D | C | Q | W | I | T | A | L | H | Y | A | F | Q | D | E | N | H | L |
| Template Known Secondary structure |   |
S |
|
| G | G | G |  |  |  |  |  |  |  |  |
|
| S | S | S |  |  |  |  |  |  |  | T | T | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | T |
|
|  |  |  |  |  |  |  |  |  |  | S |
| T | T | T | B |
|
|  |  |  |  |  |  |
| S | S |  |  |
| Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . |
|   |
|   |   |
459 | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
Y | I | I | T | E | F | M | S | H | G | N | L | L | D | F | L | R | S | A | G | R | E | T | L | D | A | V | A | L | L | Y | M | A | T | Q | I | A | S | G | M | S | Y | L | E | S | R | N | Y | I | H | R | D | L | A | A | R | N | C | L | V | G | D | N | K | L | V | K | V | A | D | F | G | L | A | R | L | M | R | D | D |
| Query Conservation |   |
  |   |
|   |
|   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |
|
|
|   |   |   |   |
|
|
|
|
|
|   |   |
|   |
|   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|
|
|   |
|
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   | . |   |
|   |
|   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |   |
|
|   |   |   |
|
|
|
|
|
|
|
|   |
|
|
|
|   |   |   |   |   |
|
|
|   |
|
|
|   |
|   |   |   |   |   |   |
| Template Sequence |   |
Y | L | V | M | D | Y | Y | V | G | G | D | L | L | T | L | L | S | K | F | E | D | . |
K | L | P | E | D | M | A | R | F | Y | I | G | E | M | V | L | A | I | D | S | I | H | Q | L | H | Y | V | H | R | D | I | K | P | D | N | V | L | L | D | V | N | G | H | I | R | L | A | D | F | G | S | C | L | K | M | N | D | D |
| Template Known Secondary structure |   |
 |  |  |  |
|
|
| T | T |  |  |  |  |  |  |  |  |  | T | T | T | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |
|
|
|
| S | G | G | G |  |  |  |
| T | T | S |
|  |  |  |
|
|
| T | T |
|  |  |
|
| T | T |
| Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | |
. | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . |
|   |
|   |   |
539 | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | |
|
|
|
|
. | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | |
|
|
|
. | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|  |  |
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
| . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . |
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
| Query Sequence |   |
T | Y | T | A | H | A | G | A | K | F | P | I | K | W | T | A | P | E | G | L | A | Y | N | K | . |
. |
. |
. |
. |
F | S | T | K | S | D | V | W | A | F | G | V | L | L | W | E | I | A | T | Y | G | M | S | P | Y | P | A | I | D | L | T | D | V | Y | H | K | L | D | K | G | Y | . |
. |
. |
. |
R | M | E | R | P | P |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |
|
|
|
|   |
|   |   |
|   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   | . | . | . | . |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
G | T | V | Q | S | S | V | A | V | G | T | P | D | Y | I | S | P | E | I | L | Q | A | M | E | D | G | M | G | K | Y | G | P | E | C | D | W | W | S | L | G | V | C | M | Y | E | M | L | Y | . |
G | E | T | P | F | Y | A | E | S | L | V | E | T | Y | G | K | I | M | N | H | E | E | R | F | Q | F | P | S | H | V | T |
| Template Known Secondary structure |   |
S |
|  |  |  | S | S |
|
| S |
| G | G | G |
|
|  |  |  |  |  |  | T | T | S | S | S |  |  |  |
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| T | T |
|
| S | S |  |  |  |  |  |  |  |  |  | T |  |  |  |  |
|
|
|
| S | S |
|
|
| Template Predicted Secondary structure |   |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
229 | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | |
. | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . |
|   |
|   |   |
610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
G | C | P | P | E | V | Y | D | L | M | R | Q | C | W | Q | W | D | A | T | D | R | P | T | F | K | S | I | H | H | A | L | E | H | M | F | Q | E | S | S | I | T | E | A | V | E | K | Q | L | N | A | N | A | T | S | A | S | S | S | A | P |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|   |   |   |   |
|
|
|   |   |
|
|   | . |   |
|   |   |
|
|   |
|   |
|   |   |
|
|
|   |
|
|
|
|   |   |
|   |
|   |   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|
| Template Sequence |   |
D | V | S | E | E | A | K | D | L | I | Q | R | L | I | C | . |
S | R | E | R | R | L | G | Q | N | G | I | E | D | F | K | K | H | A | F | F | E | G | L | N | W | E | N | I | R | N | L | E | A | P | Y | I | P | D | V | S | S | P | S | D |
| Template Known Secondary structure |   |
S | S |
|  |  |  |  |  |  |  |  | T | T | S | S | . |
| G | G | G |
| T | T | T | T | T | T |  |  |  |  | T | S | G | G | G | T | T |
|
| T | T | T | G | G | G | S |
|
| S |
|
|
|
|
| S | S | T | T |
|
| Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
| . |
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
308 | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | |
. | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . |
|   |