Return to main results Retrieve Phyre Job Id

Job DescriptionA8JNU2
Confidence100.00%DateTue Jan 22 11:54:53 GMT 2013
Rank154Aligned Residues243
% Identity44%Templatec3k54A_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: structures of human bruton's tyrosine kinase in active and inactive2 conformations suggests a mechanism of activation for tec family3 kinases.
Resolution1.94 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   379380.........390.........400.........410.........420.........430.........440.........450........
Predicted Secondary structure 


























Query SS confidence 















































































Query Sequence  PDEWEICRTDIMMKHKLGGGQYGEVYEAVWKRYGNTVAVKTLKEDTMALKDFLEEAAIMKEMKHPNLVQLIGVCTREPPF
Query Conservation                  

 
 

 
           



              
      
 
 


            
Alig confidence 






























.











.......




























Template Conservation       
          

 
 

 
 
    .    



 

 .......   

  
  
 




            
Template Sequence  YGSWEIDPKDLTFLKELGTGQFGVVKYGKWR. GQYDVAIKMIKE. . . . . . . FIEEAKVMMNLSHEKLVQLYGVCTKQRPI
Template Known Secondary structure 
GGGB

GGGSTTSS
T.TT


.......
TT


TTB


SSSS
Template Predicted Secondary structure 







.


.......















Template SS confidence 















































































   392.......400.........410.........420.. .......430.... .....440.........450.........460...
 
   459460.........470.........480.........490.........500.........510.........520.........530........
Predicted Secondary structure 



































Query SS confidence 















































































Query Sequence  YIITEFMSHGNLLDFLRSAGRETLDAVALLYMATQIASGMSYLESRNYIHRDLAARNCLVGDNKLVKVADFGLARLMRDD
Query Conservation    
 
    
 
   
                  

  

 


    





  
 
       

 




      
Alig confidence 





















.


















































......
Template Conservation    
        
          .                                            
 
    ......
Template Sequence  FIITEYMANGCLLNYLREMRHR. FQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGFP. . . . . .
Template Known Secondary structure 

TT
GGG
.

TT


S

SGGG
TT







......
Template Predicted Secondary structure 


















.























......
Template SS confidence 















































































   471........480.........490.. .......500.........510.........520.........530.........540...
 
   539540.........550.........560.........570.........580.........590.........600.........610........
Predicted Secondary structure 





































Query SS confidence 















































































Query Sequence  TYTAHAGAKFPIKWTAPEGLAYNKFSTKSDVWAFGVLLWEIATYGMSPYPAIDLTDVYHKLDKGYRMERPPGCPPEVYDL
Query Conservation                 


           



 
  
 
    
  
            
                   
Alig confidence  ...........




































































Template Conservation  ...........                  

 
 
    

 
                 
            
     
Template Sequence  . . . . . . . . . . . VRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTI
Template Known Secondary structure  ...........GGG





TTS

TTTTS
TT





TTS
Template Predicted Secondary structure  ...........











































Template SS confidence 















































































   561........570.........580.........590.........600.........610.........620.........
 
   619620.........630.........640.......
Predicted Secondary structure 







Query SS confidence 




























Query Sequence  MRQCWQWDATDRPTFKSIHHALEHMFQES
Query Conservation          
  

        
       
Alig confidence 




























Template Conservation 
  

  

  


  


  
  

   
Template Sequence  MYSCWHEKADERPTFKILLSNILDVMDEE
Template Known Secondary structure  TT
SSGGGS


Template Predicted Secondary structure 








Template SS confidence 




























   630.........640.........650........
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions