|   |   |
389 | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | |
|
|
. | . | . | . | . | . | . | . | 450 | . | . | |
|
|
|
|
|
|
|
|
. | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . |
|
|
|  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . |  |  |
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
| Query Sequence |   |
I | M | M | K | H | K | L | G | G | G | Q | Y | G | E | V | Y | E | A | V | W | K | R | Y | G | N | T | V | A | V | K | T | L | K | E | D | T | M | A | L | K | D | F | L | E | E | A | A | I | M | K | E | M | K | . |
. |
. |
H | P | N | L | V | Q | L | I | G | V | C | . |
. |
. |
. |
. |
. |
. |
. |
. |
T | R | E | P |
| Query Conservation |   |
  |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   | . | . | . |
|   |
|
|
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
| Template Conservation |   |
|   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |
|   |   |   |   |
|
|   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
L | V | R | G | T | V | L | G | Q | E | D | P | Y | A | Y | L | E | A | T | D | Q | E | T | G | E | S | F | E | V | H | V | P | Y | F | T | E | R | A | I | K | Q | M | K | E | E | V | L | R | L | R | L | L | R | G | I | K | N | Q | K | Q | A | K | V | H | L | R | F | I | F | P | F | D | L | V | K | D | P | Q | V | L |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |  |  |
|
| S |
|
|
|
|  |  |  |  |  |  |  |  | G | G | G | G | S | T | T |
|
| S |  |  |  |  |  |  |  | T |
| B |
|
|
|
|  |  |  |  |
|
|
|
|
|
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
257 | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . |
|   |
|   |   |
457 | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | |
|
|
|
|
. | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . |
| Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
P | F | Y | I | I | T | E | F | M | S | H | G | N | L | L | D | F | L | R | S | . |
. |
. |
. |
. |
A | G | R | E | T | L | D | A | V | A | L | L | Y | M | A | T | Q | I | A | S | G | M | S | Y | L | E | S | R | N | Y | I | H | R | D | L | A | A | R | N | C | L | V | G | D | N | K | L | V | K | V | A | D | F | G | L |
| Query Conservation |   |
  |   |   |   |
|   |
|   |   |   |   |
|   |
|   |   |   |
|   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |
|
|
|   |   |   |   |
|
|
|
|
|
|   |   |
|   |
|   |   |   |   |   |   |   |
|
|   |
|
|
|
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   | . |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |
|
|   |   |
|
|
|
|
|
|
|
|
|   |
|
|
|
|   |   |   |
|   |   |
|
|   |
|
|
|   |
| Template Sequence |   |
S | R | F | F | L | Y | P | R | M | . |
Q | S | N | L | Q | T | F | G | E | V | L | L | S | H | S | S | T | H | K | S | L | V | H | H | A | R | L | Q | L | T | L | Q | V | I | R | L | L | A | S | L | H | H | Y | G | L | V | H | T | Y | L | R | P | V | D | I | V | L | D | Q | R | G | G | V | F | L | T | G | F | E | H |
| Template Known Secondary structure |   |
S |  |  |  |  |  |  |
|
| . | S |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |
| S |
|
|
| G | G | G |  |  |  |
| T | T |
|
|  |  |  |
|
| G | G | G |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
356 | . | . | . | 360 | . | . | . | . | |
. | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . |
|   |
|   |   |
532 | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | |
|
|
|
. | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | |
. | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|  |  |
|
|
|
|
|
|  |  |
|
|
|
| . | . | . | . |
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
A | R | L | M | R | D | D | T | Y | T | A | H | A | G | A | . |
. |
. |
. |
K | F | P | I | K | W | T | A | P | E | G | L | A | Y | N | K | . |
F | S | T | K | S | D | V | W | A | F | G | V | L | L | W | E | I | A | T | Y | G | M | S | P | Y | P | A | I | D | L | T | D | V | Y | H | K | L | D | K | G | Y | R | M | E |
| Query Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   | . |   |   |   |   |   |
|
|
|
|   |
|   |   |
|   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
| Template Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |   |
|
|   |
|   |   | . |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |
| Template Sequence |   |
L | V | R | D | G | A | S | A | V | S | P | I | G | R | G | F | A | P | P | E | T | T | A | E | R | M | L | P | F | G | Q | H | H | P | T | L | M | T | F | A | F | D | T | W | T | L | G | L | A | I | Y | W | I | W | C | . |
A | D | L | P | N | T | D | D | A | A | L | G | G | S | E | W | I | . |
. |
. |
. |
. |
F | R |
| Template Known Secondary structure |   |
|  |  | T | T |  |  |  |
|
|
|
|
| T | T | T |
|
|  |  |  |  |  |  |  | T | S | T | T | G | G | G |
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
|
|
|
| T | T | G | G | G | S |
| S | G | G | G | . | . | . | . | . | G | S |
| Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  | . | . | . | . | . |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
435 | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | |
490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | |
|
|
|
|
. | . |
|   |
|   |   |
607 | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
R | P | P | G | C | P | P | E | V | Y | D | L | M | R | Q | C | W | Q | W | D | A | T | D | R | P | T | F | K | S | I | H | H | A | L | E | H | M | F | Q | E | S |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |
|   |   |   |   |   |
|
|   |   |   |
|   |   |
|
|   |   |
|   |
|   |   |   |   | . | . | . |
|   |   |
|   |   |   |   |
| Template Sequence |   |
S | C | K | N | I | P | Q | P | V | R | A | L | L | E | G | F | L | R | Y | P | K | E | D | R | L | L | P | L | Q | A | . |
. |
. |
M | E | T | P | E | Y | E | Q |
| Template Known Secondary structure |   |
S |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  | T |
| S | S | G | G | G | S |
|
|  |  |  |  | . | . | . | T | T | S |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  | . | . | . |  |
|
|  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
509 | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | |
|
|
. | 540 | . | . | . | . | . | . |
|   |