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Job DescriptionA8JNU2
Confidence100.00%DateTue Jan 22 11:54:53 GMT 2013
Rank111Aligned Residues247
% Identity33%Templatec3d4qA_
PDB info PDB header:transferaseChain: A: PDB Molecule:b-raf proto-oncogene serine/threonine-protein kinase; PDBTitle: pyrazole-based inhibitors of b-raf kinase
Resolution2.80 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   380.........390.........400.........410.........420.. .......430.........440.........450......
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Query Sequence  DEWEICRTDIMMKHKLGGGQYGEVYEAVWKRYGNTVAVKTLKE. . . DTMALKDFLEEAAIMKEMKHPNLVQLIGVCTREP
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Template Sequence  DDWEIPDGQITVGQRIGSGSFGTVYKGKWHGD. . . VAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKP.
Template Known Secondary structure 


B

TT

TTSSS...

SSS

TT


TTB


SS.
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   448.450.........460.........470......... 480.........490.........500.........510.........520...
 
   457..460.........470.........480.........490.........500.........510.........520.........530......
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Query Sequence  PFYIITEFMSHGNLLDFLRSAGRETLDAVALLYMATQIASGMSYLESRNYIHRDLAARNCLVGDNKLVKVADFGLARLMR
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Template Sequence  QLAIVTQWCEGSSLYHHLHIIET. KFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVL.
Template Known Secondary structure  S


SS
BTS

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TT
B
S

SGGGTTT


TT
B

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   524.....530.........540...... ...550.........560.........570.........580.........590.........600.
 
   537..540.........550.........560.. .......570.........580.........590.... .....600...... ..
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Query Sequence  DDTYTAHAGAKFPIKWTAPEGLAYNK. . . FSTKSDVWAFGVLLWEIATYGMSPYPAIDLTD. VYHKLDKGYRME. . . . RP
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Template Sequence  . . . . . . . . . . SGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMT. GQLPYSNINNRDQIIFMVGRGYLSPDLSKVR
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TT

TT
SS


S.SS
TTTT


TS



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   614.....620.........630.........640.........650. ........660.........670.........680..
 
   609610.........620.........630.........640...
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Query Sequence  PGCPPEVYDLMRQCWQWDATDRPTFKSIHHALEHM
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Template Sequence  SNCPKAMKRLMAECLKKKRDERPLFPQILASIELL
Template Known Secondary structure  TTS
T
SSGGGS

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   683......690.........700.........710.......
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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