|   |   |
379 | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | |
|
|
. | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | |
|
. | . | . | . | . | . | . | . | 450 | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|  |  |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . |
|
|
|  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
P | D | E | W | E | I | C | R | T | D | I | M | M | K | H | K | L | G | G | G | Q | Y | G | E | V | Y | E | A | V | W | K | R | Y | G | N | T | V | A | V | K | T | L | . |
. |
. |
K | E | D | T | M | A | L | K | D | F | L | E | E | A | A | I | M | K | E | M | K | . |
. |
H | P | N | L | V | Q | L | I | G | V | C | T |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   | . | . |
|   |
|
|
|   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |
|   |   |   |   |
|   |
|   |   |   |
|
|   |
|   |
|
|   |
|
|   |
|   |   |   | . |   |
|   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |
|   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |
| Template Sequence |   |
F | Q | S | M | S | V | K | G | R | I | Y | S | I | L | K | Q | I | G | S | G | G | S | S | K | V | F | Q | V | L | N | E | . |
K | K | Q | I | Y | A | I | K | Y | V | N | L | E | E | A | D | N | Q | T | L | D | S | Y | R | N | E | I | A | Y | L | N | K | L | Q | Q | H | S | D | K | I | I | R | L | Y | D | Y | E | I |
| Template Known Secondary structure |   |
|
|  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |
|
| S | S |  |  |  |  |  |  |  |
| T | . | T |
|
|  |  |  |  |  |  |  |  |
| S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | G | G | G |
| T | T | B |
|
|  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
515 | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | |
. | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . |
|   |
|   |   |
454 | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . |
| Predicted Secondary structure |   |
 |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
R | E | P | P | F | Y | I | I | T | E | F | M | S | H | G | N | L | L | D | F | L | R | S | A | G | R | E | T | L | D | A | V | A | L | L | Y | M | A | T | Q | I | A | S | G | M | S | Y | L | E | S | R | N | Y | I | H | R | D | L | A | A | R | N | C | L | V | G | D | N | K | L | V | K | V | A | D | F | G | L | A | R |
| Query Conservation |   |
  |   |   |   |   |   |   |
|   |
|   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |
|
|
|   |   |   |   |
|
|
|
|
|
|   |   |
|   |
|   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . |
| Template Conservation |   |
  |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   | . |
| Template Sequence |   |
T | D | Q | Y | I | Y | M | V | M | E | C | G | N | I | D | L | N | S | W | L | K | K | K | K | S | . |
. |
. |
I | D | P | W | E | R | K | S | Y | W | K | N | M | L | E | A | V | H | T | I | H | Q | H | G | I | V | H | S | D | L | K | P | A | N | F | L | I | V | D | . |
G | M | L | K | L | I | D | F | G | I | A | . |
| Template Known Secondary structure |   |
| S | S |  |  |  |  |  |  |
|
|
| S |  |  |  |  |  |  |  |  |  |
| S | S | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|
|
|
| G | G | G |  |  |  |  | T | . | T |  |  |  |  |
|
|
| S | S | S | . |
| Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
594 | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | |
|
|
. | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | |
. | . | 660 | . | . | . | . | . | . | . | . | |
|   |
|   |   |
534 | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | |
. | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | |
590 | . | . | . | . | . | . | . | . | . | 600 | . | . | |
. | . | . | . | . | . | . | 610 |
| Predicted Secondary structure |   |
 |
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |
|
| . |
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| Query Sequence |   |
L | M | R | D | D | T | Y | T | A | H | A | G | A | K | F | P | I | K | W | T | A | P | E | G | L | A | Y | N | K | . |
F | S | T | K | S | D | V | W | A | F | G | V | L | L | W | E | I | A | T | Y | G | M | S | P | Y | P | A | . |
I | D | L | T | D | V | Y | H | K | L | D | K | G | . |
Y | R | M | E | R | P | P | G |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   | . |   |   |   |   |   |
|
|
|
|   |
|   |   |
|   |
|   |   |   |   |
|   |   |
|   |   |   | . |   |   |   |   |   |   |   |   |   |
|   |   |   | . |   |   |   |   |   |   |   |   |
| Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|   |
|
|
|
|
|
| . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | Q | G | T | V | N | Y | M | P | P | E | A | I | K | D | M | S | K | I | S | P | K | S | D | V | W | S | L | G | C | I | L | Y | Y | M | T | Y | . |
G | K | T | P | F | Q | Q | I | I | N | Q | I | S | K | L | H | A | I | I | D | P | N | H | E | I | E | F | P | D | I |
| Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
| G | G | G |
|
|  |  |  |  | T | T |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| T | T | T | T |
|
| S |  |  |  |  |  |  |  |  |  |
| T | T | S |
|
|
|
|
|
|
|
| Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|
|
|
|
|
|
|
|
|
|
|
669 | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | |
. | . | . | . | 710 | . | . | . | . | . | . | . | . | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . |
|   |
|   |   |
611 | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
C | P | P | E | V | Y | D | L | M | R | Q | C | W | Q | W | D | A | T | D | R | P | T | F | K | S | I | H | H | A | L | E | H | M | F | Q | E | S | S |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|   |   |
|   |   |
|
|   |   |   |
|   |   |
|
|   |   |
|   |
|   |   |
|
| . | . | . |
|   |
|
|   |   |
|   |   |
| Template Sequence |   |
P | E | K | D | L | Q | D | V | L | K | C | C | L | K | R | D | P | K | Q | R | I | S | I | P | E | L | . |
. |
. |
L | A | H | P | Y | V | Q | I | Q |
| Template Known Secondary structure |   |
S |
|  |  |  |  |  |  |  |  |  |  | T |
| S | S | T | T | T | S |
|
|  |  |  |  | . | . | . |  | T | S |  |  |  |  |
|
|
| Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  | . | . | . |  |
|
|
|
|  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
760 | . | . | . | . | . | . | . | . | . | 770 | . | . | . | . | . | . | . | . | . | 780 | . | . | . | . | . | |
|
|
. | . | . | . | 790 | . | . | . | . |
|   |