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Job DescriptionA8JNU2
Confidence100.00%DateTue Jan 22 11:54:53 GMT 2013
Rank4Aligned Residues436
% Identity45%Templatec2h8hA_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: src kinase in complex with a quinazoline inhibitor
Resolution2.20 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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   210.........220.........230.........240.........250.........260.........270.........280.........
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Query Sequence  FVALYDFQAGGENQLSLKKGEQVRILSYNKSGEWCEAHSDSGNVGWVPSNYVTPLNSLEKHSWYHGPISRNAAEYLLSSG
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Template Sequence  FVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNA
Template Known Secondary structure  SS
B


SSSB

B
TT

SSSSTTT

GGGTTSGGGSTTB

S

T
T
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   86...90.........100.........110.........120.........130.........140.........150.........160.....
 
   290.........300.........310.. .......320.........330.........340.........350.........360..
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Query Sequence  . . INGSFLVRESESSPGQRSISLRY. . . . . EGRVYHYRISEDPDGKVFVTQEAKFNTLAELVHHHSVPHEGHGLITPLLY
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Template Sequence  ENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYS. . KHADGLCHRLTT
Template Known Secondary structure  T

TT
SSSTT
TTTB
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S
TTSS..

TTSSS


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   166...170.........180.........190.........200.........210.........220.........230. ........240...
 
   363......370.........380.........390.........400.........410.........420.........430.........440..
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Query Sequence  PAPKQNKPTVFPLSPEPDEWEICRTDIMMKHKLGGGQYGEVYEAVWKRYGNTVAVKTLKEDTMALKDFLEEAAIMKEMKH
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Template Sequence  VCPTSKPQTQ. . . GLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNG. TTRVAIKTLKPGTMSPEAFLQEAQVMKKLRH
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S...SSSTT
SB

GGG
SSTT.T
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   244.....250... ......260.........270.........280........ .290.........300.........310.........
 
   443......450.........460.........470.........480.........490.........500.........510.........520..
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Query Sequence  PNLVQLIGVCTREPPFYIITEFMSHGNLLDFLRSAGRETLDAVALLYMATQIASGMSYLESRNYIHRDLAARNCLVGDNK
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Template Sequence  EKLVQLYAVVS. EEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENL
Template Known Secondary structure  TTB


.SSS



TTSTT

TT


S

SGGG
GGG
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   320.........330 .........340.........350.........360.........370.........380.........390........
 
   523......530.........540.........550.........560.........570.........580.........590.........600..
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Query Sequence  LVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNKFSTKSDVWAFGVLLWEIATYGMSPYPAIDLTDVYHKLDKG
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Template Sequence  VCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERG
Template Known Secondary structure 


TTSTTT


TT
STTS
GGGS




TTTT

SSTT

TT
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   399400.........410.........420.........430.........440.........450.........460.........470........
 
   603......610.........620.........630.........640.........650..
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Query Sequence  YRMERPPGCPPEVYDLMRQCWQWDATDRPTFKSIHHALEHMFQESSITEA
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Template Sequence  YRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQQP
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TT

T
SSGGGS

TSS


S



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   479480.........490.........500.........510.........520........
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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