Return to main results Retrieve Phyre Job Id

Job DescriptionA8JNU2
Confidence100.00%DateTue Jan 22 11:54:53 GMT 2013
Rank126Aligned Residues249
% Identity39%Templatec1xkkA_
PDB info PDB header:transferaseChain: A: PDB Molecule:epidermal growth factor receptor; PDBTitle: egfr kinase domain complexed with a quinazoline inhibitor-2 gw572016
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   384.....390.........400.........410.........420.........430.........440.........450.........460...
Predicted Secondary structure 






















Query SS confidence 















































































Query Sequence  ICRTDIMMKHKLGGGQYGEVYEAVWKRYGNTVAVKTLKEDTMALKDFLEEAAIMKEMKHPNLVQLIGVCTREPPFYIITE
Query Conservation             

 
 

 
           



              
      
 
 


              
 
Alig confidence 









































..



























.






Template Conservation 
    
     

 
 

 



        



 
     ..     
   
  
 




         .       
Template Sequence  LKETEFKKIKVLGSGAFGTVYKGLWIPVKIPVAIKELREKAN. . KEILDEAYVMASVDNPHVCRLLGICLTS. TVQLITQ
Template Known Secondary structure 

TTT
SS






T..


TTB

SS.S
Template Predicted Secondary structure 








..















.






Template SS confidence 















































































   707..710.........720.........730.........740........ .750.........760.........770...... ...780...
 
   464.....470.........480.........490.........500.........510.........520.........530.........540...
Predicted Secondary structure 






































Query SS confidence 















































































Query Sequence  FMSHGNLLDFLRSAGRETLDAVALLYMATQIASGMSYLESRNYIHRDLAARNCLVGDNKLVKVADFGLARLMRDDTYTAH
Query Conservation      
 
   
                  

  

 


    





  
 
       

 




           
Alig confidence 
















.
























































.....
Template Conservation        
          .                
                                        .....
Template Sequence  LMPFGCLLDYVREHKDN. IGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAE. . . . .
Template Known Secondary structure 

TT
BTSSS.

TT


S


GGGTT


STTTT.....
Template Predicted Secondary structure 











.







































.....
Template SS confidence 















































































   792.......800........ .810.........820.........830.........840.........850.........860.....
 
   544.....550.........560.........570.........580.........590.........600.........610.........620...
Predicted Secondary structure 



































Query SS confidence 















































































Query Sequence  AGAKFPIKWTAPEGLAYNKFSTKSDVWAFGVLLWEIATYGMSPYPAIDLTDVYHKLDKGYRMERPPGCPPEVYDLMRQCW
Query Conservation            


           



 
  
 
    
  
            
                        
Alig confidence  ..













































































Template Conservation  ..                      

 
 

 



 
   
             
            
  
  

  

Template Sequence  . . EKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCW
Template Known Secondary structure  ..



TTTS




TTS

TTTTS
GGGT





TTB
T
Template Predicted Secondary structure  ..











































Template SS confidence 















































































   866...870.........880.........890.........900.........910.........920.........930.........940...
 
   624.....630.........640...
Predicted Secondary structure 





Query SS confidence 



















Query Sequence  QWDATDRPTFKSIHHALEHM
Query Conservation     
  

        
   
Alig confidence 



















Template Conservation    

  


  


  
   
Template Sequence  MIDADSRPKFRELIIEFSKM
Template Known Secondary structure 
SSGGGS

Template Predicted Secondary structure 





Template SS confidence 



















   952.......960.........970.
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions