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Job DescriptionA8JNU2
Confidence100.00%DateTue Jan 22 11:54:53 GMT 2013
Rank2Aligned Residues449
% Identity76%Templatec1oplA_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase; PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
Resolution3.42 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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   206...210.........220.........230.........240.........250.........260.........270.........280.....
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Query Sequence  DPQLFVALYDFQAGGENQLSLKKGEQVRILSYNKSGEWCEAHSDSGNVGWVPSNYVTPLNSLEKHSWYHGPISRNAAEYL
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Template Sequence  DPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQT. KNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYL
Template Known Secondary structure 
TTSS
B


STTB

B
TT

TTSS
.SS
GGGSSSGGGSTT

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   81........90.........100.........110.........120... ......130.........140.........150.........
 
   286...290.........300.........310.........320.........330.........340.........350.........360.....
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Query Sequence  LSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRISEDPDGKVFVTQEAKFNTLAELVHHHSVPHEGHGLITPLLYPAP
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Template Sequence  LSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHS. . TVADGLITTLHYPAP
Template Known Secondary structure  GGG

TT
SSSTT
TT

TTS
SSTTS
BSST..T

TTSSS




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   160.........170.........180.........190.........200.........210.........220.. .......230.......
 
   366...370.........380.........390.........400.........410.........420.........430.........440.....
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Query Sequence  KQNKPTVFPLSPEPDEWEICRTDIMMKHKLGGGQYGEVYEAVWKRYGNTVAVKTLKEDTMALKDFLEEAAIMKEMKHPNL
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Template Sequence  KRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNL
Template Known Secondary structure 

S



SSS
SSSS

B

GGGSGGGTTSSGGGT

SSSS



TTB
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   238.240.........250.........260.........270.........280.........290.........300.........310.......
 
   446...450.........460.........470.........480.........490.........500.........510.........520.....
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Query Sequence  VQLIGVCTREPPFYIITEFMSHGNLLDFLRSAGRETLDAVALLYMATQIASGMSYLESRNYIHRDLAARNCLVGDNKLVK
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Template Sequence  VQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRNLAARNCLVGENHLVK
Template Known Secondary structure 


SSSS


TT
BS
TTTS
TT
S

SGGG
GGG
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   318.320.........330.........340.........350.........360.........370.........380.........390.......
 
   526...530.........540.........550.........560.........570.........580.........590.........600.....
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Query Sequence  VADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNKFSTKSDVWAFGVLLWEIATYGMSPYPAIDLTDVYHKLDKGYRM
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Template Sequence  VADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRM
Template Known Secondary structure 

TT


TT



TT



GGG



TTS

SSTT

TTTTT


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   398.400.........410.........420.........430.........440.........450.........460.........470.......
 
   606...610.........620.........630.........640.........650.......
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Query Sequence  ERPPGCPPEVYDLMRQCWQWDATDRPTFKSIHHALEHMFQESSITEAVEKQL
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Template Sequence  ERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKEL
Template Known Secondary structure 


TT

T
SSGGGS

TS
SSS
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   478.480.........490.........500.........510.........520.........
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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