|   |   |
387 | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | |
|
|
|
. | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | |
|
|
|
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
| . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  | . | . | . | . |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
| Query Sequence |   |
T | D | I | M | M | K | H | K | L | G | G | G | Q | Y | G | E | V | Y | E | A | V | W | K | R | Y | G | N | T | V | A | V | K | T | L | K | . |
. |
. |
. |
E | D | T | M | A | L | K | D | F | L | E | E | A | A | I | M | K | E | M | K | H | P | N | L | V | Q | L | I | G | V | C | T | R | E | P | P | F | . |
. |
. |
. |
| Query Conservation |   |
  |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
| Template Conservation |   |
  |   |
|   |   |   |   |   |
|
|   |
|   |   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
D | R | Y | E | L | G | E | I | L | G | F | G | G | M | S | E | V | H | L | A | R | D | L | R | L | H | R | D | V | A | V | K | V | L | R | A | D | L | A | R | D | P | S | F | Y | L | R | F | R | R | E | A | Q | N | A | A | A | L | N | H | P | A | I | V | A | V | Y | D | T | G | E | A | E | T | P | A | G | P | L | P |
| Template Known Secondary structure |   |
T | T |  |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |  |  | S | T | T | T | T | S | S | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
| B | T | T | B |
|
|  |  |  |  |  |  |  |  |
| S | S |
|  |  |  |
| Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|  |  |  |
|
|
|
|
|
|
|
|  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
9 | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . |
|   |
|   |   |
459 | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
Y | I | I | T | E | F | M | S | H | G | N | L | L | D | F | L | R | S | A | G | R | E | T | L | D | A | V | A | L | L | Y | M | A | T | Q | I | A | S | G | M | S | Y | L | E | S | R | N | Y | I | H | R | D | L | A | A | R | N | C | L | V | G | D | N | K | L | V | K | V | A | D | F | G | L | A | R | L | M | R | D | D |
| Query Conservation |   |
  |   |
|   |
|   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |
|
|
|   |   |   |   |
|
|
|
|
|
|   |   |
|   |
|   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
| Template Conservation |   |
  |
|
|
|
|   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   | . | . | . | . | . |
| Template Sequence |   |
Y | I | V | M | E | Y | V | D | G | V | T | L | R | D | I | V | H | T | E | G | P | . |
. |
M | T | P | K | R | A | I | E | V | I | A | D | A | C | Q | A | L | N | F | S | H | Q | N | G | I | I | H | R | D | V | K | P | A | N | I | M | I | S | A | T | N | A | V | K | V | M | D | F | G | I | A | R | . |
. |
. |
. |
. |
| Template Known Secondary structure |   |
 |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  | S | S |
| S | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| B |
|
|
|
| S | G | G | G |  |  |  |  | T | T |
|
|  |  |  |
|
| T | T | S |
| B | . | . | . | . | . |
| Template Predicted Secondary structure |   |
 |  |  |  |
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
| . | . | . | . | . |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
89 | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | |
|
110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | |
|
|
|
|
|   |
|   |   |
539 | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | |
|
|
. | . | . | 610 | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|  |  |
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
T | Y | T | A | H | A | G | A | K | F | P | I | K | W | T | A | P | E | G | L | A | Y | N | K | F | S | T | K | S | D | V | W | A | F | G | V | L | L | W | E | I | A | T | Y | G | M | S | P | Y | P | A | I | D | L | T | D | V | Y | H | K | L | D | K | G | Y | R | M | E | . |
. |
. |
R | P | P | G | C | P | P | E | V |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |
|   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
. | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
. | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
| Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
A | I | T | A | Q | Y | L | S | P | E | Q | A | R | G | D | S | V | D | A | R | S | D | V | Y | S | L | G | C | V | L | Y | E | V | L | T | . |
G | E | P | P | F | T | G | D | S | P | V | S | V | A | Y | Q | H | V | R | E | D | P | I | P | P | S | A | R | H | E | G | L | S | A | D | L |
| Template Known Secondary structure |   |
. | . | . | . | . | . | . | . |
|
|
|
| S | S |
|
|  |  |  |  |  | T |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | . | S | S |
| S |
|
|
| S | S |  |  |  |  |  |  |  |  |  |  | S |
|
|
|
| S | S | S | S | S | S |
|
|
|  |  |  |
| Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
| . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|
|
|
|
|
|
|
162 | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | |
. | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . |
|   |
|   |   |
616 | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | |
. | . | . | . | . | . | . | . | 640 | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
Y | D | L | M | R | Q | C | W | Q | W | D | A | T | D | R | P | . |
T | F | K | S | I | H | H | A | L | E | H | M | F |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
| . |   |   |   |   |   |   |   |   |
|   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|
|   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
| Template Sequence |   |
D | A | V | V | L | K | A | L | A | K | N | P | E | N | R | Y | Q | T | A | A | E | M | R | A | D | L | V | R | V | H |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  | T |
| S | S | G | G | G | S |
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
248 | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . |
|   |