|   |
227 | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | |
|
|
|
. | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . |
|
|  |  |  |  |  |
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | L | A | D | G | V | E | R | G | I | L | T | A | N | R | M | I | P | G | P | S | I | Q | V | C | E | N | D | K | V | V | I | D | V | E | N | H | M | E | G | . |
. |
. |
. |
M | E | V | T | I | H | W | H | G | I | W | Q | R | G | S | Q | Y | Y | D | G | V | P | F | V | T | Q | C | P | I | Q | Q | G | N | T | F | R |
Query Conservation |   |
|   |   |
|
|   |   |
|   |
|   |   |
|
|
|
|   |
|
|
|   |
|   |
|   |   |
|
|   |
|   |
|   |
|   |
|   |
|   |   | . | . | . | . |
|   |
|
|
|
|
|
|
|
|   |
|   |   |
|
|   |
|
|
|
|
|   |
|
|
|
|
|
|   |
|
|   |
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |   |   |
|
|   | . |
|
|
|
|
|   |   |   |   |
|
|   |
|   |
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |
|
|   |
|   |   |
|
|   |
|
|   |
|
|   |   |   |   |
Template Sequence |   |
V | S | P | D | G | F | T | R | A | G | I | L | V | N | G | V | . |
H | G | P | L | I | R | G | G | K | N | D | N | F | E | L | N | V | V | N | D | L | D | N | P | T | M | L | R | P | T | S | I | H | W | H | G | L | F | Q | R | G | T | N | W | A | D | G | A | D | G | V | N | Q | C | P | I | S | P | G | H | A | F | L |
Template Known Secondary structure |   |
 |
| T | T | S |
|
|  |  |  |  |  |  | T | T | B | . | S | S |
|  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  |
|
|
|
| T | T | S |
|
| S | B |
|  |  |  |  | T |
|
|
| T | T |
| G | G | G | S |
|
| B | T | T | T | B |
|
| B |
| T | T |
|  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
| . |
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
16 | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | |
. | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . |
  |
  |   |
303 | . | . | . | |
|
. | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 |
Predicted Secondary structure |   |
 |  |  |  | . | . |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | Q | W | T | . |
. |
G | N | A | G | T | H | F | W | H | A | H | T | G | L | Q | K | L | D | G | L | Y | G | S | V | V | V | R | Q | P | P | S | R | D | P | N | S | H | L | Y | D | F | D | L | T | T | H | I | M | L | I | S | D | W | L | H | E | D | A | A | E | R | Y | P | G | R | L | A | V | N | T | G | Q | D | P |
Query Conservation |   |
|   |
|   | . | . |
|
|   |
|
|
|
|
|
|
|
|
|
|   |
|   |   |
|
|
|   |
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |
|   |
|
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
Alig confidence |   |
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |   |   |   |
|
|   |
|
|
|   |
|   |   |   |
|   |   |   |
|
|   |
|   |
|
|
|   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |
Template Sequence |   |
Y | K | F | T | P | A | G | H | A | G | T | F | W | Y | H | S | H | F | G | T | Q | Y | C | D | G | L | R | G | P | M | V | I | Y | D | D | N | D | P | . |
. |
H | A | A | L | Y | D | E | D | D | E | N | T | I | I | T | L | A | D | W | Y | H | I | P | A | P | S | I | . |
. |
. |
. |
. |
. |
. |
Q | G | A | A | Q | P |
Template Known Secondary structure |   |
 |  |  |
|
| T | T |
|
|  |  |  |  |  |  |  |
| S | T | T | G | G | G | G | T |
|  |  |  |  |  |  |  |
| T | T |
| T | . | . | T | G | G | G |
| S | B |
| S | G | G | G |  |  |  |  |  |  |  |
| S | S |
| G | G | G |
| . | . | . | . | . | . | . |
| S | S |
|
|
|
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  | . | . | . | . | . | . | . |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
95 | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | |
|
. | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
160 | . | . | . | . | . |
  |
  |   |
381 | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 |
Predicted Secondary structure |   |
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |
|
|  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | S | M | L | I | N | G | K | G | Q | F | R | D | P | N | T | G | F | M | T | N | T | P | L | E | I | F | T | I | T | P | G | R | R | Y | R | F | R | M | I | N | A | F | A | S | V | C | P | A | Q | V | T | I | E | G | H | G | M | T | V | I | A | T | D | G | E | P | V | H | P | V | D | V | N | T | I | I | S | F | S |
Query Conservation |   |
|
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |   |   |   |
|
|
|
|
|
|   |
|
|
|
|
|   |
|
|   |   |
|
|
|   |   |
|
|   |
|   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|
|   |
|   |   |   |   |   | . | . | . | . | . |
|   |   |   |   |
|   |
|   |
|   |   |
|   |   |   |
|
|
|
|
|
|
|   |   |   |   |   | . |   |   |
|   |
|   |
|   |   |   |   |
|
|
|   |
|
|   |   |   |   |
|   |   |   |   |   |
|   |
|   |
|
Template Sequence |   |
D | A | T | L | I | N | G | K | G | R | Y | V | G | G | . |
. |
. |
. |
. |
P | A | A | E | L | S | I | V | N | V | E | Q | G | K | K | Y | R | M | R | L | I | S | L | S | C | D | P | N | . |
W | Q | F | S | I | D | G | H | E | L | T | I | I | E | V | D | G | E | L | T | E | P | H | T | V | D | R | L | Q | I | F | T |
Template Known Secondary structure |   |
S |  |  |  |  | T | T | B |
|
| B | T | T |
| . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |
| T | T |
|  |  |  |  |  |  |  |  |
|
| S | S |
|
| . |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  | S | B |  |  |  |
| T |
Template Predicted Secondary structure |   |
|
|  |  |  |
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  | . |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
166 | . | . | . | 170 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | |
. | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . |
  |
  |   |
461 | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | |
|
|
|
|
. | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | E | R | Y | D | F | V | I | S | A | D | Q | P | V | G | A | Y | W | I | Q | L | R | G | L | G | E | C | G | . |
. |
. |
. |
. |
I | R | R | A | Q | Q | L | A | I | L | R | Y | A | R | G | P | Y | Q | P | A | S | S | P | P | T | Y | D | V | G | I | P | Q | G | V | I | L | N | P | L | D | A | I | C | D | R | K | R |
Query Conservation |   |
|
|
|
|
|
|
|
|   |
|   |
|   |   |
|   |
|   |
|
|   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
|
|
|   |
|
|
|
|   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
G | Q | R | Y | S | F | V | L | D | A | N | Q | P | V | D | N | Y | W | I | R | A | Q | P | N | K | G | R | N | G | L | A | G | T | F | A | N | G | V | N | S | A | I | L | R | Y | A | G | A | A | N | A | D | P | T | T | S | A | N | P | N | P | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
T |
|  |  |  |  |  |  |  |
|
| S |
| S | S |  |  |  |  |  |  |  |  | S |
|
| G | G | G | G | G | G |
|
| G | G | G | T | T |  |  |  |  |  |  | T | T | S |
| S | S |
|
|
|
|
|
|
| S | S |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
536 | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | D | A | V | C | V | S | N | L | K | N | A | K | K | V | D | K | G | V | L | V | E | R | P | D | V | K | I | F | L | P | F | R | F | F | V | Y | E | P | K | A | L | F | I | P | N | T | Y | N | R | F | L | V | V | P | S | G | D | H | L | T | S | L | V | D | E | I | S | Y | I | S | P | P | A | P | P | L | S | Q | I |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |
|
|   |   |   |
|   |   |
|   |
|   |   |   |
Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
Template Sequence |   |
. |
. |
Q | L | N | E | A | D | L | H | A | L | I | D | P | A | A | P | G | I | P | T | P | G | A | A | D | V | N | L | R | F | Q | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | F | S | G | G | R | F | T | I | N | G | T | A | Y | E | S | P | S | V | P | T | L | L | Q | I |
Template Known Secondary structure |   |
. | . | B |
|
| G | G | G |
| B | B | S | S | S |
| S |
| S | S |
| S | S | T | T |
| S | S |  |  |  |  |
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
| S | S | S |  |  |  | T | T | B |
|
|
|
|
| S | S |
|  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
302 | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . |
  |
  |   |
616 | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | D | I | P | P | E | Y | F | C | N | G | D | N | R | P | P | N | C | G | P | N | C | E | C | T | H | M | V | D | I | P | L | G | A | I | V | E | V | V | L | V | D | E | V | Q | Q | V | N | L | S | H | P | F | H | L | H | G | T | A | F | Y | V | V | G | L | G | R | S | P | D | K | S | I | K | K | I | N | L | K | H |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |
|   |
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|   |
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |   |   |
|   |   |   | . | . |   |   |   |
|
|   |
|
|
|
|   |   |
|   |
|
|   |   |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
M | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | A | Q | S | A | N | D | L | L | P | A | G | S | V | Y | E | L | P | R | N | Q | V | V | E | L | V | V | P | A | G | V | L | . |
. |
G | G | P | H | P | F | H | L | H | G | H | A | F | S | V | V | R | S | A | G | S | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 | T | . | . | . | . | . | . | . | . | . | . | . | T |
|
| S | G | G | G | S | S | S | T | T | S |  |  |  |  |
| S | S |
|  |  |  |  |  |  |  |
|
| S | T | . | . | T |
|
|
|  |  |  |  | T | T |
|
|  |  |  |  |  |
| T | T |
|
| . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
| . | . |
|
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
359 | 360 | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | |
|
. | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
  |
  |   |
696 | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | . | . | . | 720 | . | . | |
. | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . | . | 750 | . | . | . | . | . | . | . | . | . | 760 | . | |
|
|
. | . | . | . | . | . | . | . | 770 | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
| . |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | L | E | L | D | Q | M | G | M | L | E | R | H | F | S | K | P | P | L | K | D | T | I | A | V | P | N | . |
N | G | Y | V | V | I | R | F | R | A | D | N | P | G | Y | W | L | F | H | C | H | F | L | F | H | I | V | I | G | M | N | L | I | F | H | I | G | T | T | . |
. |
. |
A | D | L | P | P | V | P | P | R | F |
Query Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |   |
|
|   |
|
|
|   |
|
|
|
|   |
|
|
| . |
|
|   |
|
|
|
|
|   |
|
|
|
|
|   |
|
|
|
|
|
|
|
|   |
|   |   |   |
|
|   |   |
|
|   |
|
|   |   | . | . | . |   |   |   |   |
|   |
|   |   |
|
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |
|
|
|
|   |
|
|
|   |
|   |   |
|   |
|
|
|   |
|
|   |   |
|   |
|   |   |
|
|
|
|
|   |
|   |
|   |
|
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | Y | N | F | V | N | P | V | K | R | D | V | V | S | L | G | V | T | G | D | E | V | T | I | R | F | V | T | D | N | P | G | P | W | F | F | H | C | H | I | E | F | H | L | M | N | G | L | A | I | V | F | A | E | D | M | A | N | T | V | D | A | N | N | P | P | V | E | W | A |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . |
|
|
| S | S | S | B |
|  |  | S |  |  |  |
|
| S | T | T |
|  |  |  |  |  |  |  |
|
| S |
|  |  |  |  |  |  |  | S | S |  |  |  |  | T | T | T |
|  |  |  |  |  |  |
| G | G | G |  |  |  |  |
|
|
|
|  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
415 | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . |
  |
  |   |
772 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
Query Sequence |   |
P | T | C | G | D | H |
Query Conservation |   |
|   |
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |
Template Sequence |   |
Q | L | C | E | I | Y |
Template Known Secondary structure |   |
 |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
  |   |
485 | . | . | . | . | 490 |
  |