|   |   |
521 | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | |
. | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | |
|
|
. | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | |
|
|
|
| Predicted Secondary structure |   |
 |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
| . | . | . | . |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
| Query Sequence |   |
I | H | P | M | E | L | M | L | M | E | E | L | G | S | G | Q | F | G | V | V | R | R | G | K | W | R | . |
G | S | I | D | T | A | V | K | M | M | K | E | G | T | M | S | E | D | D | . |
. |
. |
F | I | E | E | A | K | V | M | T | K | L | Q | H | P | N | L | V | Q | L | Y | G | V | C | S | K | H | R | . |
. |
. |
. |
| Query Conservation |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   | . |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |
|   |   |   |
|   |   |
|   |
|
|
|
|
|   |   |   |
|   |   |   |   |   |   | . | . | . | . |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
| Template Conservation |   |
  |   |   |
|
|   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
N | D | G | R | F | L | K | F | D | I | E | I | G | R | G | S | F | K | T | V | Y | K | G | L | D | T | E | T | T | V | E | V | A | W | C | E | L | Q | D | R | K | L | T | K | S | E | R | Q | R | F | K | E | E | A | E | X | L | K | G | L | Q | H | P | N | I | V | R | F | Y | D | S | W | E | S | T | V | K | G | K | K |
| Template Known Secondary structure |   |
T | T | S |
|  |  |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |  |  |  | G | G | G | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
| T | T | B |
|
|  |  |  |  |  |  |  |  | S | S | S |
|  |
| Template Predicted Secondary structure |   |
 |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
216 | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . |
|   |
|   |   |
593 | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | |
|
. | . | . | . | . | . | . | 650 | . | . | . | . | . | . | |
. | . | . | 660 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |
|
|
|
|
|  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
P | I | Y | I | V | T | E | Y | M | K | H | G | S | L | L | N | Y | L | R | R | H | E | K | T | L | I | G | N | M | G | L | L | L | D | M | C | I | Q | V | S | K | G | M | T | Y | L | E | R | H | N | . |
. |
Y | I | H | R | D | L | A | A | R | N | C | L | V | G | . |
S | E | N | V | V | K | V | A | D | F | G | L | A |
| Query Conservation |   |
  |   |   |
|
|   |
|   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |
|
|
|   |   |   | . | . |
|
|
|
|
|
|
|   |   |
|
|
|
|   | . |   |   |   |   |
|
|
|   |
|
|
|
|
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
C | I | V | L | V | T | E | L | X | T | S | G | T | L | K | T | Y | L | K | R | F | K | . |
. |
. |
V | X | K | I | K | V | L | R | S | W | C | R | Q | I | L | K | G | L | Q | F | L | H | T | R | T | P | P | I | I | H | R | D | L | K | C | D | N | I | F | I | T | G | P | T | G | S | V | K | I | G | D | L | G | L | A |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |
|
|
| S |
| B |  |  |  |  |  |  |  |  | S | . | . | . | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S | S | S |
|
|
|
| S |
|
|
| G | G | G |  |  |  | S | S | T | T | S |
|  |  |  |
|
| T | T | G | G |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
296 | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | |
|
|
. | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . |
|   |
|   |   |
670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | . | . | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | |
|
740 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
| . | . |
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
| Query Sequence |   |
R | Y | V | L | D | D | Q | Y | T | S | S | G | G | T | K | F | P | I | K | W | A | P | P | E | V | L | N | Y | T | R | F | S | S | K | S | D | V | W | A | Y | G | V | L | M | W | E | I | F | T | C | G | K | M | P | Y | G | R | L | K | N | T | E | V | V | E | R | V | Q | R | G | . |
. |
I | I | L | E | K | P | K | S |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |
|   |   |
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   | . | . |   |   |   |   |   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |
|
| . |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |   |
|
|   |   |
|   | . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
T | L | K | R | A | S | F | A | K | A | V | I | G | T | P | E | . |
. |
. |
F | X | A | P | E | . |
X | Y | E | E | K | Y | D | E | S | V | D | V | Y | A | F | G | X | C | X | L | E | X | A | T | . |
S | E | Y | P | Y | S | E | C | Q | N | A | A | Q | I | Y | R | R | V | T | S | G | V | K | P | A | S | F | D | K | V |
| Template Known Secondary structure |   |
G | G |
|
| T | T | S |
|
|
| S |
| S | S |
|
| . | . | . |
|
|
| G | G | . | G | G | G | T |
|
|
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| T | T | T | T |
| S | S |  |  |  |  |  |  |  |  | T | T | T |
|
|
| G | G | G | G | G |
|
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|  |  |  | . |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
373 | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | |
|
|
. | 390 | . | . | . | |
. | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | |
. | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . |
|   |
|   |   |
748 | . | 750 | . | . | . | . | . | . | . | . | . | 760 | . | . | . | . | . | . | . | . | . | 770 | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
C | A | K | E | I | Y | D | V | M | K | L | C | W | S | H | G | P | E | E | R | P | A | F | R | V | L | M | D |
| Query Conservation |   |
  |   |   |   |   |   |   |
|
|   |   |
|   |   |   |
|
|   |   |
|
|
|   |   |   |
|
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |
|
|   |   |   |
|   |   |
|
|   |   |
|
|
|   |   |
|
|
|   |
| Template Sequence |   |
A | I | P | E | V | K | E | I | I | E | G | C | I | R | Q | N | K | D | E | R | Y | S | I | K | D | L | L | N |
| Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  | S |
| S | S | G | G | G | S |
|
|  |  |  |  |  | T |
| Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
448 | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . |
|   |