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Job DescriptionP08630
Confidence100.00%DateWed Feb 13 11:12:46 GMT 2013
Rank7Aligned Residues379
% Identity33%Templatec4fl2A_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase syk; PDBTitle: structural and biophysical characterization of the syk activation2 switch
Resolution2.19 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   401........410.........420..... ....430.........440.........450.........460.........470.........
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Query Sequence  ALLGLERYEWYVGDMSRQRAESLLK. QGDKEGCFVVRKSSTKGLYTLSLHTKVPQSHVKHYHIKQNARCEYYLSEKHCCE
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Template Sequence  ATTAHEKMPWFHGKISREESEQIVLIGSKTNGKFLIRARDNNGSYALCLLH. . . EGKVLHYRIDKDKTGKLSIPEGKKFD
Template Known Secondary structure  TTS
GGGSTTB

S

SSS

TT
TTT...TT
TTS
STT


BS
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   159160.........170.........180.........190.........200......... 210.........220.........230.....
 
   480.........490.........500...... ...510.........520.........530. ........540..
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Query Sequence  TIPDLINYHRHNSGGLACRLKSSPCDR. . . . . . . . . . . . . . . . PVPPTAGLSHDKWEIHPMELMLMEE. LGSGQFGVVRR
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Template Sequence  TLWQLVEHYSYKADGLLRVLTVPCQKIGTQREALPMDTEVYESPYADPEEIRPKEVYLDRKLLTLEDKELGSGNFGTVKK
Template Known Secondary structure  STTB
TTSSS


SB


S


TT

GGGSGGGS
GGGSTTS


SSSB

GGGTT
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   236...240.........250.........260.........270.........280.........290.........300.........310.....
 
   543... ...550......... 560.........570.........580.........590.........600.........610......
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Query Sequence  GKWR. . . GSIDTAVKMMKEG. . . TMSEDDFIEEAKVMTKLQHPNLVQLYGVCSKHRPIYIVTEYMKHGSLLNYLRRHEKT
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Template Sequence  GYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGIC. EAESWMLVMEMAELGPLNKYLQQNR. .
Template Known Secondary structure  TT
SGGG
GGG


TTB

.SSS

TT
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   388.390.........400.........410.........420.........430......... 440.........450.........460....
 
   617..620.........630.........640.........650.........660.........670...... ...680.........690....
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Query Sequence  LIGNMGLLLDMCIQVSKGMTYLERHNYIHRDLAARNCLVGSENVVKVADFGLARYVLDDQ. . YTSSGGTKFPIKWAPPEV
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Template Sequence  . HVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPEC
Template Known Secondary structure  .TS
TT


S

SGGGTT

TTTT

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BTTB
GGGG

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   465....470.........480.........490.........500.........510.........520.........530.........540...
 
   695....700.........710.........720.........730.........740.........750.........760.........770....
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Query Sequence  LNYTRFSSKSDVWAYGVLMWEIFTCGKMPYGRLKNTEVVERVQRGIILEKPKSCAKEIYDVMKLCWSHGPEERPAFRVLM
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Template Sequence  INYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVE
Template Known Secondary structure 



TTT

SSTT

TT





TT

T
SSTTTS

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   544.....550.........560.........570.........580.........590.........600.........610.........620...
 
   775....780......
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Query Sequence  DQLALVAQTLTD
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Template Sequence  LRLRNYYYDVVN
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   624.....630.....
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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