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Job DescriptionP08630
Confidence100.00%DateWed Feb 13 11:12:46 GMT 2013
Rank133Aligned Residues260
% Identity30%Templatec4e1zA_
PDB info PDB header:transferase/transferase inhibitorChain: A: PDB Molecule:non-receptor tyrosine-protein kinase tyk2; PDBTitle: structure of mouse tyk-2 complexed to a 3-aminoindazole inhibitor
Resolution2.50 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   520.........530.........540....... ..550.........560... ......570.........580.........590..
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Query Sequence  EIHPMELMLMEELGSGQFGVVRRGKWRG. . . . . SIDTAVKMMKEGTMSE. . DDFIEEAKVMTKLQHPNLVQLYGVCSKHR
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Template Sequence  VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKEGCGPQLRSGWQREIEILRTLYHEHIVKYKGCCEDKS
Template Known Secondary structure  B

GGG
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   887..890.........900.........910.........920.........930.........940.........950.........960......
 
   593......600.........610.........620.........630.........640.........650.........660.........670..
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Query Sequence  PIYIVTEYMKHGSLLNYLRRHEKTLIGNMGLLLDMCIQVSKGMTYLERHNYIHRDLAARNCLVGSENVVKVADFGLARYV
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Template Sequence  VQLVMEYVPLGSLRDYLPRHCV. . . . . GLAQLLLFAQQICEGMAYLHAQHYIHRALAARNVLLDNDRLVKIGDFGLAKAV
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   970.........980.........990. ........1000.........1010.........1020.........1030.........1040....
 
   673......680..... ....690.........700.........710.........720...... ...730.....
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Query Sequence  LDDQYTSSGGTKF. . PIKWAPPEVLNYTRFSSKSDVWAYGVLMWEIFTCGKMPYGR. . . . . . . . . . . . . . . LKNTEVVER
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Template Sequence  PEGHEYYRVREDGDSPVFWYAPECLKECKFYYASDVWSFGVTLYELLT. YCDSNQSPHTKFTELIGHTQGQMTVLRLTEL
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   1045....1050.........1060.........1070.........1080.........1090.. .......1100.........1110.........1120...
 
   736...740.........750.........760.........770.........780.....
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Query Sequence  VQRGIILEKPKSCAKEIYDVMKLCWSHGPEERPAFRVLMDQLALVAQTLT
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Template Sequence  LERGERLPRPDRCPCEIYHLMKNCWETEASFRPTFQNLVPILQTAQEKYQ
Template Known Secondary structure  T





TT

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   1124.....1130.........1140.........1150.........1160.........1170...
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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