Return to main results Retrieve Phyre Job Id

Job DescriptionP08630
Confidence100.00%DateWed Feb 13 11:12:46 GMT 2013
Rank110Aligned Residues242
% Identity55%Templatec3k54A_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: structures of human bruton's tyrosine kinase in active and inactive2 conformations suggests a mechanism of activation for tec family3 kinases.
Resolution1.94 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   516...520.........530.........540.........550.........560.........570.........580.........590.....
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Query Sequence  HDKWEIHPMELMLMEELGSGQFGVVRRGKWRGSIDTAVKMMKEGTMSEDDFIEEAKVMTKLQHPNLVQLYGVCSKHRPIY
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Template Sequence  YGSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKE. . . . . . . FIEEAKVMMNLSHEKLVQLYGVCTKQRPIF
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GGGB

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   392.......400.........410.........420.........430.... .....440.........450.........460....
 
   596...600.........610.........620.........630.........640.........650.........660.........670.....
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Query Sequence  IVTEYMKHGSLLNYLRRHEKTLIGNMGLLLDMCIQVSKGMTYLERHNYIHRDLAARNCLVGSENVVKVADFGLARYVLDD
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Template Sequence  IITEYMANGCLLNYLREMRHRF. . QTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGFP. . . . . .
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   472.......480.........490... ......500.........510.........520.........530.........540...
 
   676...680.........690.........700.........710.........720.........730.........740.........750.....
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Query Sequence  QYTSSGGTKFPIKWAPPEVLNYTRFSSKSDVWAYGVLMWEIFTCGKMPYGRLKNTEVVERVQRGIILEKPKSCAKEIYDV
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Template Sequence  . . . . . . . . . . . VRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTI
Template Known Secondary structure  ...........GGG





TTS

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   561........570.........580.........590.........600.........610.........620.........
 
   756...760.........770.........780...
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Query Sequence  MKLCWSHGPEERPAFRVLMDQLALVAQT
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Template Sequence  MYSCWHEKADERPTFKILLSNILDVMDE
Template Known Secondary structure  TT
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   630.........640.........650.......
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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