|   |   |
521 | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | |
. | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | |
|
. | . | . | . | . | . |
| Predicted Secondary structure |   |
 |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
| . | . |
|  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
| Query Sequence |   |
I | H | P | M | E | L | M | L | M | E | E | L | G | S | G | Q | F | G | V | V | R | R | G | K | W | R | . |
G | S | I | D | T | A | V | K | M | M | K | E | G | T | M | S | E | D | D | F | I | E | E | A | K | V | M | T | K | L | Q | H | P | N | L | V | Q | L | Y | G | V | C | S | K | H | . |
. |
R | P | I | Y | I | V |
| Query Conservation |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   | . |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|
|
|
|
|   |   |   |
|   |   |   |   |   | . | . |   |   |   |   |
|
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|   |   |
|   |
|   |   |   |
| . | . |
|   |   |
|   |
|   |   |   |   |   |   |   |
|   |   |   |
|
|
|
|   |
|   |   |   | . | . | . | . |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
| Template Sequence |   |
V | Q | L | N | Q | Y | T | L | K | D | E | I | . |
. |
G | K | Y | G | V | V | K | L | A | Y | N | E | N | D | N | T | Y | Y | A | M | K | V | L | S | K | K | . |
. |
. |
. |
E | Q | V | Y | Q | E | I | A | I | L | K | K | L | D | H | P | N | V | V | K | L | V | E | V | L | D | D | P | N | E | D | H | L | Y | M | V |
| Template Known Secondary structure |   |
|  |  | T | T |  |  |  |  |  |  |  | . | . |  |
|
|
|  |  |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . |
|  |  |  |  |  |  |  |  |  |  | T |
|
|
| T | T | B |
|
|  |  |  |  |  |  |
| S | S | S | S |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  | . | . |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|  |  | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
161 | . | . | . | . | . | . | . | . | 170 | . | . | |
|
. | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | |
|
|
|
. | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . |
|   |
|   |   |
598 | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
T | E | Y | M | K | H | G | S | L | L | N | Y | L | R | R | H | E | K | T | L | I | G | N | M | G | L | L | L | D | M | C | I | Q | V | S | K | G | M | T | Y | L | E | R | H | N | Y | I | H | R | D | L | A | A | R | N | C | L | V | G | S | E | N | V | V | K | V | A | D | F | G | L | A | R | Y | V | L | D | D | Q | Y |
| Query Conservation |   |
  |
|   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |
|
|
|   |   |   |
|
|
|
|
|
|
|   |   |
|
|
|
|   |   |   |   |   |
|
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |
|   |
|   |
|
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
F | E | L | V | N | Q | G | P | V | M | E | V | P | T | L | K | P | . |
. |
. |
. |
L | S | E | D | Q | A | R | F | Y | F | Q | D | L | I | K | G | I | E | Y | L | H | Y | Q | K | I | I | H | R | D | I | K | P | S | N | L | L | V | G | E | D | G | H | I | K | I | A | D | F | G | V | S | N | E | F | K | G | S | D | A |
| Template Known Secondary structure |   |
 |  |
|
| T | T |
| B | S |
|
| S | S |
| S | S |
| . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |
|
|
|
|
| G | G | G |  |  |  |
| T | T | S |
|  |  |  |
|
|
| T | T |
|  |  |
| S | S | S | S |
|
| Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
268 | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | |
|
|
|
. | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . |
|   |
|   |   |
678 | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | |
|
|
700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | . | . | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | |
740 | . | . | . | . | . | . | . | . | . | 750 | . | . | . |
| Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
| . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
| . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
T | S | S | G | G | T | K | F | P | I | K | W | A | P | P | E | V | L | N | Y | T | R | . |
. |
. |
F | S | S | K | S | D | V | W | A | Y | G | V | L | M | W | E | I | F | T | C | G | K | M | P | Y | G | R | L | K | N | T | E | V | V | E | R | V | Q | R | G | . |
I | I | L | E | K | P | K | S | C | A | K | E | I | Y |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |   |   | . | . | . |   |   |   |
|
|
|
|
|
|   |
|   |   |
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   | . |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
| Alig confidence |   |
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  | . |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |
|
|
|
|
|
|   | . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
L | . |
L | S | N | T | V | G | T | P | A | F | M | A | P | E | S | L | S | E | T | R | K | I | F | S | G | K | A | L | D | V | W | A | M | G | V | T | L | Y | C | F | V | F | . |
G | Q | C | P | F | M | D | E | R | I | M | C | L | H | S | K | I | K | S | Q | A | L | E | F | P | D | Q | P | D | I | A | E | D | L | K |
| Template Known Secondary structure |   |
 | . |  |
|
|
|
| S |
| G | G | G |
|
| G | G | G |
|
| T | T |
|
|
|  |  | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| S | S |
|
| S | S |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| S | S | S |
|
|
|  |  |  |  |
| Template Predicted Secondary structure |   |
| . |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
344 | |
. | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | |
. | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . |
|   |
|   |   |
754 | . | . | . | . | . | 760 | . | . | . | . | . | . | . | . | . | 770 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
D | V | M | K | L | C | W | S | H | G | P | E | E | R | P | A | F | R | V | L | M | D | Q | L | A | L |
| Query Conservation |   |
  |
|
|   |   |
|   |   |   |
|
|   |   |
|
|
|   |   |   |
|
|   |   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|
|   |   |   |
|   |   |
|
|   |   |
|
|
|   |   |
|
|
|   |
|
|   |   |
| Template Sequence |   |
D | L | I | T | R | M | L | D | K | N | P | E | S | R | I | V | V | P | E | I | K | L | H | P | W | V |
| Template Known Secondary structure |   |
 |  |  |  |  |  | T |
| S |
| T | T | T | S |
|
|  |  |  |  | T | T |
|  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
422 | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . |
|   |