Job Description P08630 Confidence 100.00% Date Wed Feb 13 11:12:46 GMT 2013 Rank 270 Aligned Residues 245 % Identity 17% Template c2pvmA_ PDB info PDB header:transferase Chain: A: PDB Molecule:casein kinase ii subunit alpha; PDBTitle: structure-based design of pyrazolo[1,5-a][1,3,5]triazine2 derivatives as potent inhibitors of protein kinase ck2 Resolution 2.00 Å

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		521	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.		.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.			.	.	.	.	.
Predicted Secondary structure																											.																																																.	.
Query SS confidence																											.																																																.	.
Query Sequence		I	H	P	M	E	L	M	L	M	E	E	L	G	S	G	Q	F	G	V	V	R	R	G	K	W	.	R	G	S	I	D	T	A	V	K	M	M	K	E	G	T	M	S	E	D	D	F	I	E	E	A	K	V	M	T	K	L	Q	H	P	N	L	V	Q	L	Y	G	V	C	S	K	H	R	.	.	P	I	Y	I	V
Query Conservation																											.																																																.	.
Alig confidence																											.															.	.																																.	.
Template Conservation																																										.	.
Template Sequence		G	E	Q	D	D	Y	E	V	V	R	K	V	G	R	G	K	Y	S	E	V	F	E	G	I	N	V	N	N	N	E	K	C	I	I	K	I	L	K	P	V	.	.	K	K	K	K	I	K	R	E	I	K	I	L	Q	N	L	G	G	P	N	I	V	K	L	L	D	I	V	R	D	Q	H	S	K	T	P	S	L	I
Template Known Secondary structure				G	G	G											S	S									T	T	T											S		.	.																		T	T	B										T	T	T
Template Predicted Secondary structure																																										.	.
Template SS confidence
		34	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.			.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.
		598	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.		.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.
Predicted Secondary structure																																																												.
Query SS confidence																																																												.
Query Sequence		T	E	Y	M	K	H	G	S	L	L	N	Y	L	R	R	H	E	K	T	L	I	G	N	M	G	L	L	L	D	M	C	I	Q	V	S	K	G	M	T	Y	L	E	R	H	N	Y	I	H	R	D	L	A	A	R	N	C	L	V	.	G	S	E	N	V	V	K	V	A	D	F	G	L	A	R	Y	V	L	D	D	Q
Query Conservation																																																												.
Alig confidence																		.	.	.	.	.	.																																					.
Template Conservation																		.	.	.	.	.	.
Template Sequence		F	E	Y	V	N	N	T	D	F	K	V	L	Y	P	T	L	.	.	.	.	.	.	T	D	Y	D	I	R	Y	Y	I	Y	E	L	L	K	A	L	D	Y	C	H	S	Q	G	I	M	H	R	D	V	K	P	H	N	V	M	I	D	H	E	L	R	K	L	R	L	I	D	W	G	L	A	E	F	Y	H	P	G	K
Template Known Secondary structure														G	G	G		.	.	.	.	.	.																						T	T							S	G	G	G					T	T	T	T								T	T						T	T
Template Predicted Secondary structure																		.	.	.	.	.	.
Template SS confidence
		113	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.							.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.
		677	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.		.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.
Predicted Secondary structure																							.																																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																							.																																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		Y	T	S	S	G	G	T	K	F	P	I	K	W	A	P	P	E	V	L	N	Y	.	T	R	F	S	S	K	S	D	V	W	A	Y	G	V	L	M	W	E	I	F	T	C	G	K	M	P	Y	G	R	L	K	N	T	E	V	V	E	R	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation																							.																																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence											.	.											.																																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation											.	.
Template Sequence		E	Y	N	V	R	V	A	S	R	.	.	Y	F	K	G	P	E	L	L	V	D	L	Q	D	Y	D	Y	S	L	D	M	W	S	L	G	C	M	F	A	G	M	I	F	R	K	E	P	F	F	Y	G	H	D	N	H	D	Q	L	V	K	I	A	K	V	L	G	T	D	G	L	N	A	Y	L	N	K	Y	R	I	E
Template Known Secondary structure					S			S		G	.	.	G	G							T	T			S			T																	T		S	S	S	S			S	S																								T	T
Template Predicted Secondary structure											.	.
Template SS confidence
		187	.	.	190	.	.	.	.	.			.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.
																		736	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	V	Q	R	G	I	I	L	E	K	P	K	S	C	A	K	E	I	Y	D	V	M	K	L	C	W	S	H	G	P	E	E	R	P	A	F	R	V	L	M	D
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		L	D	P	Q	L	E	A	L	V	G	R	H	S	R	K	P	W	L	K	F	M	N	A	D	N	Q	H	L	V	S	P	E	A	I	D	F	L	D	K	L	L	R	Y	D	H	Q	E	R	L	T	A	L	E	A	M	T
Template Known Secondary structure																		G	G	G	G			T	T	T	G	G	G											T	T			S	S	T	T	T	S
Template Predicted Secondary structure
Template SS confidence
		265	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions