Job Description P08630 Confidence 100.00% Date Wed Feb 13 11:12:46 GMT 2013 Rank 108 Aligned Residues 250 % Identity 37% Template c1xkkA_ PDB info PDB header:transferase Chain: A: PDB Molecule:epidermal growth factor receptor; PDBTitle: egfr kinase domain complexed with a quinazoline inhibitor-2 gw572016 Resolution 2.40 Å

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		521	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.		.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																												.
Query SS confidence																												.
Query Sequence		I	H	P	M	E	L	M	L	M	E	E	L	G	S	G	Q	F	G	V	V	R	R	G	K	W	R	.	G	S	I	D	T	A	V	K	M	M	K	E	G	T	M	S	E	D	D	F	I	E	E	A	K	V	M	T	K	L	Q	H	P	N	L	V	Q	L	Y	G	V	C	S	K	H	R	P	I	Y	I	V	T	E
Query Conservation																												.
Alig confidence																												.														.	.																																	.
Template Conservation																																										.	.																																	.
Template Sequence		L	K	E	T	E	F	K	K	I	K	V	L	G	S	G	A	F	G	T	V	Y	K	G	L	W	I	P	V	K	I	P	V	A	I	K	E	L	R	E	K	.	.	A	N	K	E	I	L	D	E	A	Y	V	M	A	S	V	D	N	P	H	V	C	R	L	L	G	I	C	L	T	S	T	V	.	Q	L	I	T	Q
Template Known Secondary structure				T	T	T											S	S																								.	.	T																	T	T	B									S	S	S		.
Template Predicted Secondary structure																																										.	.																																	.
Template SS confidence
		707	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.			.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.		.	780	.	.	.
		600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	M	K	H	G	S	L	L	N	Y	L	R	R	H	E	K	T	L	I	G	N	M	G	L	L	L	D	M	C	I	Q	V	S	K	G	M	T	Y	L	E	R	H	N	Y	I	H	R	D	L	A	A	R	N	C	L	V	G	S	E	N	V	V	K	V	A	D	F	G	L	A	R	Y	V	L	D	D	Q	Y	T	S
Query Conservation
Alig confidence																				.	.																																																						.	.	.	.	.	.	.
Template Conservation																				.	.																																																						.	.	.	.	.	.	.
Template Sequence		L	M	P	F	G	C	L	L	D	Y	V	R	E	H	K	D	N	I	.	.	G	S	Q	Y	L	L	N	W	C	V	Q	I	A	K	G	M	N	Y	L	E	D	R	R	L	V	H	R	D	L	A	A	R	N	V	L	V	K	T	P	Q	H	V	K	I	T	D	F	G	L	A	K	L	L	.	.	.	.	.	.	.
Template Known Secondary structure				T	T		B								T	S	S	S		.	.																						T	T				S				G	G	G						T	T								S					T	.	.	.	.	.	.	.
Template Predicted Secondary structure																				.	.																																																						.	.	.	.	.	.	.
Template SS confidence
		792	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.			810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.
		680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	G	G	T	K	F	P	I	K	W	A	P	P	E	V	L	N	Y	T	R	F	S	S	K	S	D	V	W	A	Y	G	V	L	M	W	E	I	F	T	C	G	K	M	P	Y	G	R	L	K	N	T	E	V	V	E	R	V	Q	R	G	I	I	L	E	K	P	K	S	C	A	K	E	I	Y	D	V	M	K	L	C
Query Conservation
Alig confidence
Template Conservation
Template Sequence		G	A	E	E	K	V	P	I	K	W	M	A	L	E	S	I	L	H	R	I	Y	T	H	Q	S	D	V	W	S	Y	G	V	T	V	W	E	L	M	T	F	G	S	K	P	Y	D	G	I	P	A	S	E	I	S	S	I	L	E	K	G	E	R	L	P	Q	P	P	I	C	T	I	D	V	Y	M	I	M	V	K	C
Template Known Secondary structure		T	T	T					T	T	T	S																												T	T	S			T	T	T	T	S		G	G	G								T							T	T	B
Template Predicted Secondary structure
Template SS confidence
		863	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.
		760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		W	S	H	G	P	E	E	R	P	A	F	R	V	L	M	D	Q	L	A	L	V	A	Q
Query Conservation
Alig confidence
Template Conservation
Template Sequence		W	M	I	D	A	D	S	R	P	K	F	R	E	L	I	I	E	F	S	K	M	A	R
Template Known Secondary structure		T		S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		951	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions