Job Description P08630 Confidence 100.00% Date Wed Feb 13 11:12:46 GMT 2013 Rank 3 Aligned Residues 427 % Identity 41% Template c1oplA_ PDB info PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase; PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase Resolution 3.42 Å

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		347	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	V	A	L	Y	P	F	K	A	I	E	G	G	D	L	S	L	E	K	N	A	E	Y	E	V	I	D	D	S	Q	E	H	W	W	K	V	K	D	A	L	G	N	V	G	Y	I	P	S	N	Y	V	K	P	K	A	L	L	G	L	E	R	Y	E	W	Y	V	G	D	M	S	R	Q	R	A	E	S	L	L	K	Q
Query Conservation
Alig confidence																																																									.	.
Template Conservation																																																									.	.
Template Sequence		F	V	A	L	Y	D	F	V	A	S	G	D	N	T	L	S	I	T	K	G	E	K	L	R	V	L	G	Y	N	H	N	G	E	W	C	E	A	Q	T	K	N	G	Q	G	W	V	P	S	N	Y	I	T	P	V	N	.	.	S	L	E	K	H	S	W	Y	H	G	P	V	S	R	N	A	A	E	Y	L	L	S	S
Template Known Secondary structure					S	S		B				S	T	T	B			B		T	T										T	T	S	S							S	S							G	G	G				S	S	.	.	S	G	G	G	S	T	T														G	G	G
Template Predicted Secondary structure																																																									.	.
Template SS confidence
		85	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.			140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.
		427	.	.	430	.	.	.	.	.	.	.	.	.	440		.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.
Predicted Secondary structure																.
Query SS confidence																.
Query Sequence		G	D	K	E	G	C	F	V	V	R	K	S	S	T	.	K	G	L	Y	T	L	S	L	H	T	K	V	P	Q	S	H	V	K	H	Y	H	I	K	Q	N	A	R	C	E	Y	Y	L	S	E	K	H	C	C	E	T	I	P	D	L	I	N	Y	H	R	H	N	S	G	G	L	A	C	R	L	K	S	S	P	C	D
Query Conservation																.
Alig confidence		.														.											.	.	.
Template Conservation		.																									.	.	.
Template Sequence		.	G	I	N	G	S	F	L	V	R	E	S	E	S	S	P	G	Q	R	S	I	S	L	R	Y	.	.	.	E	G	R	V	Y	H	Y	R	I	N	T	A	S	D	G	K	L	Y	V	S	S	E	S	R	F	N	T	L	A	E	L	V	H	H	H	S	T	V	A	D	G	L	I	T	T	L	H	Y	P	A	P	K
Template Known Secondary structure		.			T	T								S	S	S	T	T									.	.	.	T	T											T	T	S				S	S	T	T	S		B	S	S									T	T			T	T	S	S	S
Template Predicted Secondary structure		.																									.	.	.
Template SS confidence
			163	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.				.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.
				506	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.		.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.
Predicted Secondary structure		.	.																																											.
Query SS confidence		.	.																																											.
Query Sequence		.	.	R	P	V	P	P	T	A	G	L	S	H	D	K	W	E	I	H	P	M	E	L	M	L	M	E	E	L	G	S	G	Q	F	G	V	V	R	R	G	K	W	R	G	.	S	I	D	T	A	V	K	M	M	K	E	G	T	M	S	E	D	D	F	I	E	E	A	K	V	M	T	K	L	Q	H	P	N	L	V
Query Conservation		.	.																																											.
Alig confidence		.	.																																											.
Template Conservation
Template Sequence		R	N	K	P	T	V	Y	G	V	S	P	N	Y	D	K	W	E	M	E	R	T	D	I	T	M	K	H	K	L	G	G	G	Q	Y	G	E	V	Y	E	G	V	W	K	K	Y	S	L	T	V	A	V	K	T	L	K	E	D	T	M	E	V	E	E	F	L	K	E	A	A	V	M	K	E	I	K	H	P	N	L	V
Template Known Secondary structure			S					S	S	S		S	S	S	S			B			G	G	G							S	G	G	G	T	T	S	S							G	G	G	T										S	S	S	S																		T	T	B
Template Predicted Secondary structure
Template SS confidence
		239	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.
		583	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Q	L	Y	G	V	C	S	K	H	R	P	I	Y	I	V	T	E	Y	M	K	H	G	S	L	L	N	Y	L	R	R	H	E	K	T	L	I	G	N	M	G	L	L	L	D	M	C	I	Q	V	S	K	G	M	T	Y	L	E	R	H	N	Y	I	H	R	D	L	A	A	R	N	C	L	V	G	S	E	N	V	V	K
Query Conservation
Alig confidence																																				.
Template Conservation																																				.
Template Sequence		Q	L	L	G	V	C	T	R	E	P	P	F	Y	I	I	T	E	F	M	T	Y	G	N	L	L	D	Y	L	R	E	C	N	R	Q	.	E	V	N	A	V	V	L	L	Y	M	A	T	Q	I	S	S	A	M	E	Y	L	E	K	K	N	F	I	H	R	N	L	A	A	R	N	C	L	V	G	E	N	H	L	V	K
Template Known Secondary structure									S	S	S	S									T	T		B								S		T	T	.	T	S																						T	T				S			S	G	G	G					G	G	G
Template Predicted Secondary structure																																				.
Template SS confidence
		319	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.		.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.
		663	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	A	D	F	G	L	A	R	Y	V	L	D	D	Q	Y	T	S	S	G	G	T	K	F	P	I	K	W	A	P	P	E	V	L	N	Y	T	R	F	S	S	K	S	D	V	W	A	Y	G	V	L	M	W	E	I	F	T	C	G	K	M	P	Y	G	R	L	K	N	T	E	V	V	E	R	V	Q	R	G	I	I	L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		V	A	D	F	G	L	S	R	L	M	T	G	D	T	Y	T	A	H	A	G	A	K	F	P	I	K	W	T	A	P	E	S	L	A	Y	N	K	F	S	I	K	S	D	V	W	A	F	G	V	L	L	W	E	I	A	T	Y	G	M	S	P	Y	P	G	I	D	L	S	Q	V	Y	E	L	L	E	K	D	Y	R	M
Template Known Secondary structure					T	T						T	T							T	T					G	G	G																													T	T	S			S	S	T	T			T	T	T							T	T
Template Predicted Secondary structure
Template SS confidence
		398	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.
		743	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780
Predicted Secondary structure
Query SS confidence
Query Sequence		E	K	P	K	S	C	A	K	E	I	Y	D	V	M	K	L	C	W	S	H	G	P	E	E	R	P	A	F	R	V	L	M	D	Q	L	A	L	V
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	R	P	E	G	C	P	E	K	V	Y	E	L	M	R	A	C	W	Q	W	N	P	S	D	R	P	S	F	A	E	I	H	Q	A	F	E	T	M
Template Known Secondary structure					T	T													T		S	S	G	G	G	S												T	S
Template Predicted Secondary structure
Template SS confidence
		478	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.