Phyre 2 Results for Q7KV33

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Email | l.a.kelley@imperial.ac.uk
Description | Q7KV33
Date | Tue Jan 22 11:34:33 GMT 2013
Unique Job ID | d95adb05d880fe9d

Summary |

Top model
Image coloured by rainbow N → C terminus
| Close Jmol

Model (left) based on template c2eo6A_
Top template information
PDB header:signaling protein Chain: A: PDB Molecule:b-cell linker protein; PDBTitle: solution structure of the sh2 domain from mouse b-cell2 linker protein blnk
Confidence and coverage
Confidence: | 99.9% | Coverage: | 7%
101 residues ( 7% of your sequence) have been modelled with 99.9% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
181 residues ( 12%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
Warning: 75% of your sequence is predicted disordered. Disordered regions cannot be meaningfully predicted.
3D viewing
Interactive 3D view in Jmol

Sequence analysis |

Secondary structure and disorder prediction |

|  | 1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60
Sequence |  | M | F | C | R | L | C | W | I | D | F | N | A | G | E | A | M | V | E | C | A | G | P | C | G | S | C | F | H | R | N | C | V | D | C | V | T | G | D | V | A | H | I | L | A | T | G | G | G | Y | Y | S | G | L | E | W | Y | C | R | T | C
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120
Sequence |  | R | Q | L | Y | R | L | Q | V | Y | F | E | I | A | I | C | D | D | Y | S | L | P | V | D | F | V | K | K | R | P | S | S | F | D | P | C | L | A | E | A | I | P | A | N | P | E | H | W | I | A | P | S | P | Q | T | E | F | L | P | F | G
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180
Sequence |  | E | A | Q | Q | A | L | Q | L | Q | P | A | A | A | A | A | T | A | A | A | T | T | S | A | A | A | A | A | N | A | T | A | A | A | P | Q | L | P | P | P | L | P | V | P | V | A | T | L | P | N | Q | A | A | T | A | A | A | A | A | T | A
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240
Sequence |  | A | I | L | A | T | H | Q | Q | Q | Q | Q | Q | Q | H | Q | H | L | S | N | N | N | N | N | G | G | S | T | H | G | Q | Q | H | T | H | S | N | N | N | N | T | L | P | V | G | A | Q | Q | Q | Q | Q | Q | Q | H | Q | Q | Q | R | A | T | L
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  | ? |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300
Sequence |  | Q | H | P | P | L | P | N | S | N | I | K | Q | A | S | V | K | L | I | E | G | Y | S | D | P | K | D | T | R | N | H | K | K | V | Y | H | K | K | A | K | K | R | S | T | T | G | H | K | R | H | Q | Q | Q | Q | Q | Q | Q | Q | P | H | Q
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360
Sequence |  | Q | Q | L | Q | Q | Q | Q | Q | Q | T | L | P | T | P | R | S | A | Q | Q | Q | Q | Q | L | Q | Q | K | L | Q | Q | R | H | S | T | Y | N | N | N | N | G | N | S | R | K | D | K | R | N | S | Q | Y | N | S | D | S | S | A | P | K | S | S
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420
Sequence |  | D | D | E | A | D | I | D | E | E | V | E | Q | Q | P | L | P | V | P | Q | A | P | V | Q | S | A | S | Q | P | A | A | G | L | N | S | P | D | S | I | S | D | D | L | V | R | P | L | P | P | Q | L | Q | R | S | P | R | K | L | T | V | A
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480
Sequence |  | P | A | E | H | N | K | R | Q | P | S | P | Y | Y | Y | S | D | L | L | K | S | R | D | K | D | K | D | K | D | K | D | K | D | K | D | K | D | K | D | K | D | K | D | K | D | K | D | K | E | R | D | K | D | R | E | D | F | K | L | K | C
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540
Sequence |  | R | Q | S | T | A | S | E | P | P | Q | Q | T | Q | T | Q | L | G | G | Y | R | K | S | S | S | L | D | V | P | P | A | E | E | Q | P | E | A | E | S | H | E | E | E | D | P | R | T | G | Q | D | S | Q | S | T | P | K | R | Y | S | F | T
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600
Sequence |  | E | E | G | V | H | I | I | R | C | E | T | P | S | T | S | T | S | E | E | S | D | C | S | E | C | L | K | R | R | E | W | H | A | R | A | L | A | L | V | R | K | T | C | N | V | Q | P | R | N | Q | N | P | T | G | S | E | L | Q | L | Q
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  | ? | ? |  |  | ? | ? | ? | ? |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660
Sequence |  | L | Q | H | C | D | A | G | E | G | E | L | L | K | C | C | P | P | P | P | A | P | A | E | N | Q | S | Q | V | Q | P | M | P | P | H | R | L | L | G | P | A | A | V | C | G | A | C | I | T | S | A | P | A | S | S | L | A | G | G | R | G
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  | ? | ? |  | ? |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | . | . | . | 720
Sequence |  | S | E | L | G | D | D | L | E | E | E | Y | F | R | P | R | S | I | F | Y | V | H | P | H | G | V | H | E | C | I | E | C | A | Q | P | A | Q | P | A | T | V | P | A | P | T | L | S | N | P | S | L | D | I | Y | G | D | D | E | D | E | V
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . | . | 750 | . | . | . | . | . | . | . | . | . | 760 | . | . | . | . | . | . | . | . | . | 770 | . | . | . | . | . | . | . | . | . | 780
Sequence |  | D | G | D | E | D | E | D | E | E | D | D | S | E | D | I | M | G | S | R | R | R | Q | I | Y | E | T | A | F | D | C | K | I | A | K | S | D | D | D | L | D | E | V | D | R | I | T | N | C | S | V | L | L | Q | L | S | N | G | N | G | G
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  | ? | ? |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 790 | . | . | . | . | . | . | . | . | . | 800 | . | . | . | . | . | . | . | . | . | 810 | . | . | . | . | . | . | . | . | . | 820 | . | . | . | . | . | . | . | . | . | 830 | . | . | . | . | . | . | . | . | . | 840
Sequence |  | D | I | S | K | V | T | G | S | S | K | T | R | A | E | C | K | R | A | K | N | S | K | N | Q | A | L | Q | E | Q | T | G | E | A | H | V | Q | V | H | H | V | E | A | E | L | G | K | L | Q | L | S | Q | V | D | Q | Q | N | Q | N | Q | N
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 850 | . | . | . | . | . | . | . | . | . | 860 | . | . | . | . | . | . | . | . | . | 870 | . | . | . | . | . | . | . | . | . | 880 | . | . | . | . | . | . | . | . | . | 890 | . | . | . | . | . | . | . | . | . | 900
Sequence |  | Q | S | Q | N | Q | Q | H | G | V | S | A | T | G | S | G | A | S | A | S | S | T | Q | Q | L | P | V | R | G | Y | T | P | S | P | P | S | T | A | P | L | P | M | K | F | P | G | K | H | D | R | Y | L | N | M | N | S | I | R | S | A | P
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  | ? |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 910 | . | . | . | . | . | . | . | . | . | 920 | . | . | . | . | . | . | . | . | . | 930 | . | . | . | . | . | . | . | . | . | 940 | . | . | . | . | . | . | . | . | . | 950 | . | . | . | . | . | . | . | . | . | 960
Sequence |  | N | L | P | A | A | N | P | A | H | P | R | L | R | D | L | R | L | P | I | Q | S | M | R | H | Q | C | G | G | S | S | N | D | N | S | L | T | D | S | A | Y | V | N | P | P | S | T | N | S | N | S | N | A | A | S | A | S | A | S | A | S
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 970 | . | . | . | . | . | . | . | . | . | 980 | . | . | . | . | . | . | . | . | . | 990 | . | . | . | . | . | . | . | . | . | 1000 | . | . | . | . | . | . | . | . | . | 1010 | . | . | . | . | . | . | . | . | . | 1020
Sequence |  | V | S | A | T | G | S | A | A | P | R | R | P | R | S | F | V | L | E | S | G | R | V | L | E | L | R | R | S | A | Q | G | H | Q | G | G | Q | S | T | H | H | H | H | H | H | H | H | H | A | P | G | S | R | R | N | R | H | G | Q | S | Q
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 1030 | . | . | . | . | . | . | . | . | . | 1040 | . | . | . | . | . | . | . | . | . | 1050 | . | . | . | . | . | . | . | . | . | 1060 | . | . | . | . | . | . | . | . | . | 1070 | . | . | . | . | . | . | . | . | . | 1080
Sequence |  | G | Q | T | T | G | G | G | H | N | Y | S | S | T | E | S | I | A | T | S | S | S | G | G | S | M | E | S | L | R | S | S | T | S | E | G | N | R | S | T | S | S | S | E | S | R | H | S | S | S | L | S | S | H | S | S | E | S | G | S | G
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 1090 | . | . | . | . | . | . | . | . | . | 1100 | . | . | . | . | . | . | . | . | . | 1110 | . | . | . | . | . | . | . | . | . | 1120 | . | . | . | . | . | . | . | . | . | 1130 | . | . | . | . | . | . | . | . | . | 1140
Sequence |  | G | S | G | G | S | G | G | S | S | V | A | Y | P | L | R | P | A | P | L | L | L | H | S | K | L | H | I | L | S | P | I | S | D | K | S | S | Q | E | P | A | S | A | S | A | S | E | Q | S | Q | Q | P | S | Q | Q | L | A | P | M | A | S
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  | ? | ? | ? | ? | ? | ? | ? | ? | ? |  | ? |  |  |  | ? |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 1150 | . | . | . | . | . | . | . | . | . | 1160 | . | . | . | . | . | . | . | . | . | 1170 | . | . | . | . | . | . | . | . | . | 1180 | . | . | . | . | . | . | . | . | . | 1190 | . | . | . | . | . | . | . | . | . | 1200
Sequence |  | Q | E | D | D | S | T | T | S | G | A | P | A | G | N | Q | V | Q | V | N | A | S | L | K | Q | P | R | S | N | R | G | A | P | N | K | A | L | L | Q | L | A | D | E | L | L | G | S | D | S | G | I | S | L | H | S | R | E | D | G | K | P
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  | ? |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 1210 | . | . | . | . | . | . | . | . | . | 1220 | . | . | . | . | . | . | . | . | . | 1230 | . | . | . | . | . | . | . | . | . | 1240 | . | . | . | . | . | . | . | . | . | 1250 | . | . | . | . | . | . | . | . | . | 1260
Sequence |  | Q | A | L | A | L | Q | R | L | T | L | P | K | L | Q | L | I | G | A | E | G | T | T | T | S | A | T | A | S | G | A | G | G | S | S | A | T | G | G | S | S | G | A | G | G | S | G | S | G | S | V | V | A | S | G | S | T | G | I | Q | Q
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 1270 | . | . | . | . | . | . | . | . | . | 1280 | . | . | . | . | . | . | . | . | . | 1290 | . | . | . | . | . | . | . | . | . | 1300 | . | . | . | . | . | . | . | . | . | 1310 | . | . | . | . | . | . | . | . | . | 1320
Sequence |  | D | L | R | D | L | P | F | D | M | P | K | L | R | R | R | K | T | L | Q | Q | E | A | A | C | T | S | G | S | A | T | S | V | D | L | G | E | L | P | F | D | M | P | K | L | R | R | R | L | R | A | N | Q | A | E | I | N | N | L | L | M
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? |  |  | ? | ? | ? | ? | ? |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  | ? | ? | ? | ? |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 1330 | . | . | . | . | . | . | . | . | . | 1340 | . | . | . | . | . | . | . | . | . | 1350 | . | . | . | . | . | . | . | . | . | 1360 | . | . | . | . | . | . | . | . | . | 1370 | . | . | . | . | . | . | . | . | . | 1380
Sequence |  | H | S | T | E | S | S | G | I | S | Q | A | S | S | S | H | S | M | R | D | D | Q | K | M | S | S | K | L | D | T | A | L | F | R | Q | N | L | T | L | N | L | N | E | S | R | Q | A | T | K | Q | F | G | S | L | D | L | R | G | L | N | S
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  | ? |  |  |  |  | ? |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 1390 | . | . | . | . | . | . | . | . | . | 1400 | . | . | . | . | . | . | . | . | . | 1410 | . | . | . | . | . | . | . | . | . | 1420 | . | . | . | . | . | . | . | . | . | 1430 | . | . | . | . | . | . | . | . | . | 1440
Sequence |  | N | K | E | L | N | M | N | L | S | Q | G | Y | V | T | A | V | D | L | I | D | V | T | I | P | L | E | R | Q | G | W | Y | H | G | A | I | T | R | I | E | A | E | T | T | L | R | P | L | S | E | G | S | F | L | V | R | N | C | E | S | T
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 1450 | . | . | . | . | . | . | . | . | . | 1460 | . | . | . | . | . | . | . | . | . | 1470 | . | . | . | . | . | . | . | . | . | 1480 | . | . | . | . | . | . | . | . | . | 1490 | . | . | . | . | . | . | . | . | . | 1500
Sequence |  | K | Q | D | Y | S | L | S | L | K | G | A | K | G | F | M | H | M | R | I | Q | R | N | E | T | G | Q | Y | I | L | G | Q | F | S | R | P | F | E | T | V | P | E | M | I | R | H | F | C | L | N | R | L | P | V | R | G | A | E | H | M | C
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 1510
Sequence |  | L | I | E | P | V | I | A | Q | L | L
Secondary structure |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  | ? | ? |  | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)

? | Disordered
| Alpha helix
| Beta strand

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| c2eo6A_ |

### PDB 2eo6 chain A

Region: 1405 - 1505
Aligned: 101
Modelled: 101
Confidence: 99.9%
Identity: 31%
PDB header:signaling protein
Chain: A: PDB Molecule:b-cell linker protein;
PDBTitle: solution structure of the sh2 domain from mouse b-cell2 linker protein blnk

Phyre2
2 |
| c2hdxB_ |

### PDB 2hdx chain B

Region: 1404 - 1505
Aligned: 99
Modelled: 102
Confidence: 99.8%
Identity: 27%
PDB header:signaling protein
Chain: B: PDB Molecule:sh2-b ph domain containing signaling mediator 1
PDBTitle: crystal structure of the src homology-2 domain of sh2-b in2 complex with jak2 ptyr813 phosphopeptide

Phyre2
3 |
| c2eo3A_ |

### PDB 2eo3 chain A

Region: 1391 - 1505
Aligned: 108
Modelled: 115
Confidence: 99.8%
Identity: 27%
PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of the sh2 domain from human crk-like2 protein

Phyre2
4 |
| c3hizB_ |

### PDB 3hiz chain B

Region: 1405 - 1505
Aligned: 96
Modelled: 101
Confidence: 99.8%
Identity: 29%
PDB header:transferase/oncoprotein
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit
PDBTitle: crystal structure of p110alpha h1047r mutant in complex with2 nish2 of p85alpha

Phyre2
5 |
| d1mila_ |

### PDB 1mil chain A

Region: 1404 - 1509
Aligned: 101
Modelled: 104
Confidence: 99.8%
Identity: 33%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2
6 |
| d2shpa2 |

### PDB 2shp chain A domain 2

Region: 1406 - 1505
Aligned: 98
Modelled: 100
Confidence: 99.8%
Identity: 27%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2
7 |
| d1fhsa_ |

### PDB 1fhs chain A

Region: 1403 - 1505
Aligned: 101
Modelled: 103
Confidence: 99.8%
Identity: 29%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2
8 |
| c2gsbA_ |

### PDB 2gsb chain A

Region: 1400 - 1505
Aligned: 100
Modelled: 106
Confidence: 99.8%
Identity: 30%
PDB header:signaling protein
Chain: A: PDB Molecule:ras gtpase-activating protein 1;
PDBTitle: solution structure of the second sh2 domain of human ras2 gtpase-activating protein 1

Phyre2
9 |
| c2hmhA_ |

### PDB 2hmh chain A

Region: 1404 - 1505
Aligned: 102
Modelled: 102
Confidence: 99.8%
Identity: 24%
PDB header:cytokine regulator
Chain: A: PDB Molecule:suppressor of cytokine signaling 3;
PDBTitle: crystal structure of socs3 in complex with gp130(ptyr757)2 phosphopeptide.

Phyre2
10 |
| c2eobA_ |

### PDB 2eob chain A

Region: 1397 - 1509
Aligned: 106
Modelled: 113
Confidence: 99.8%
Identity: 28%
PDB header:hydrolase
Chain: A: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate
PDBTitle: solution structure of the second sh2 domain from rat plc2 gamma-2

Phyre2
11 |
| c3gqiB_ |

### PDB 3gqi chain B

Region: 1396 - 1510
Aligned: 107
Modelled: 111
Confidence: 99.8%
Identity: 28%
PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:phospholipase c-gamma-1;
PDBTitle: crystal structure of activated receptor tyrosine kinase in complex2 with substrates

Phyre2
12 |
| c2kk6A_ |

### PDB 2kk6 chain A

Region: 1404 - 1505
Aligned: 97
Modelled: 100
Confidence: 99.8%
Identity: 33%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fer;
PDBTitle: solution structure of sh2 domain of proto-oncogene tyrosine-2 protein kinase fer from homo sapiens, northeast structural3 genomics consortium (nesg) target hr3461d

Phyre2
13 |
| d1pica_ |

### PDB 1pic chain A

Region: 1404 - 1508
Aligned: 103
Modelled: 105
Confidence: 99.8%
Identity: 26%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2
14 |
| d1qada_ |

### PDB 1qad chain A

Region: 1402 - 1507
Aligned: 101
Modelled: 106
Confidence: 99.8%
Identity: 27%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2
15 |
| c2vifA_ |

### PDB 2vif chain A

Region: 1405 - 1505
Aligned: 101
Modelled: 101
Confidence: 99.8%
Identity: 35%
PDB header:signaling protein
Chain: A: PDB Molecule:suppressor of cytokine signalling 6;
PDBTitle: crystal structure of socs6 sh2 domain in complex with a c-kit2 phosphopeptide

Phyre2
16 |
| c2crhA_ |

### PDB 2crh chain A

Region: 1405 - 1505
Aligned: 99
Modelled: 101
Confidence: 99.8%
Identity: 26%
PDB header:signaling protein
Chain: A: PDB Molecule:vav proto-oncogene;
PDBTitle: solution structure of the sh2 domain of human proto-2 oncogene protein vav1

Phyre2
17 |
| d3c7ia1 |

### PDB 3c7i chain A domain 1

Region: 1405 - 1505
Aligned: 99
Modelled: 101
Confidence: 99.8%
Identity: 28%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2
18 |
| d1a81e2 |

### PDB 1a81 chain E domain 2

Region: 1403 - 1505
Aligned: 97
Modelled: 102
Confidence: 99.8%
Identity: 27%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2
19 |
| c2dlzA_ |

### PDB 2dlz chain A

Region: 1401 - 1505
Aligned: 103
Modelled: 105
Confidence: 99.8%
Identity: 17%
PDB header:signaling protein
Chain: A: PDB Molecule:protein vav-2;
PDBTitle: solution structure of the sh2 domain of human protein vav-2

Phyre2
20 |
| c2lqnA_ |

### PDB 2lqn chain A

Region: 1404 - 1502
Aligned: 97
Modelled: 97
Confidence: 99.8%
Identity: 25%
PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of crkl

Phyre2
21 |
22 |
23 |
24 |
25 |
26 |
27 |
28 |
29 |
30 |
31 |
32 |
33 |
34 |
35 |
36 |
37 |
38 |
39 |
40 |
41 |
42 |
43 |
44 |
45 |
46 |
47 |
48 |
49 |
50 |
51 |
52 |
53 |
54 |
55 |
56 |
57 |
58 |
59 |
60 |
61 |
62 |
63 |
64 |
65 |
66 |
67 |
68 |
69 |
70 |
71 |
72 |
73 |
74 |
75 |
76 |
77 |
78 |
79 |
80 |
81 |
82 |
83 |
84 |
85 |
86 |
87 |
88 |
89 |
90 |
91 |
92 |
93 |
94 |
95 |
96 |
97 |
98 |
99 |
100 |
101 |
102 |
103 |
104 |
105 |
106 |
107 |
108 |
109 |
110 |
111 |
112 |
113 |
| c2vpdA_ |

### PDB 2vpd chain A

Region: 3 - 61
Aligned: 54
Modelled: 54
Confidence: 95.4%
Identity: 28%
PDB header:gene regulation
Chain: A: PDB Molecule:pygopus homolog 1;
PDBTitle: decoding of methylated histone h3 tail by the pygo-bcl9 wnt2 signaling complex

Phyre2
114 |
| c3lqiA_ |

### PDB 3lqi chain A

Region: 2 - 61
Aligned: 55
Modelled: 55
Confidence: 94.7%
Identity: 24%
PDB header:transferase
Chain: A: PDB Molecule:mll1 phd3-bromo;
PDBTitle: crystal structure of mll1 phd3-bromo complexed with h3(1-9)k4me22 peptide

Phyre2
115 |
| c2kyuA_ |

### PDB 2kyu chain A

Region: 1 - 64
Aligned: 59
Modelled: 59
Confidence: 94.7%
Identity: 20%
PDB header:transferase
Chain: A: PDB Molecule:histone-lysine n-methyltransferase mll;
PDBTitle: the solution structure of the phd3 finger of mll

Phyre2
116 |
| c2xb1A_ |

### PDB 2xb1 chain A

Region: 3 - 61
Aligned: 54
Modelled: 54
Confidence: 94.2%
Identity: 28%
PDB header:transcription
Chain: A: PDB Molecule:pygopus homolog 2, b-cell cll/lymphoma 9-like protein;
PDBTitle: crystal structure of the human pygo2 phd finger in complex with the2 b9l hd1 domain

Phyre2
117 |
118 |
119 |
120 |
121 |
122 |
123 |
124 |
125 |
126 |
127 |
128 |
129 |
130 |
131 |
132 |
133 |
134 |
135 |
136 |
137 |
138 |
139 |
140 |
141 |
142 |
143 |
144 |
145 |
146 |
147 |
148 |
149 |
150 |
151 |
152 |
153 |
154 |
155 |
156 |
157 |
158 |
159 |
160 |
| d1zvfa1 |

### PDB 1zvf chain A domain 1

Region: 8 - 79
Aligned: 64
Modelled: 64
Confidence: 51.7%
Identity: 23%
Fold: Double-stranded beta-helix
Superfamily: RmlC-like cupins
Family: 3-hydroxyanthranilic acid dioxygenase-like

Phyre2
161 |
162 |
163 |
164 |
165 |
166 |
167 |
168 |
169 |
170 |
171 |
172 |
173 |
174 |
175 |
176 |
177 |
178 |
179 |
180 |
181 |
182 |
183 |
184 |
185 |
186 |
187 |
188 |
189 |
190 |
191 |
192 |
193 |
194 |
195 |
196 |
197 |
198 |
199 |
200 |
201 |
202 |
203 |
204 |
205 |
206 |
207 |
208 |
209 |
210 |
211 |
212 |
213 |
214 |
215 |
216 |
217 |
218 |
219 |
220 |
221 |
222 |
223 |
224 |
225 |
226 |
227 |
228 |
229 |
230 |
231 |
232 |
233 |
234 |
235 |
236 |
237 |
238 |
239 |
240 |
241 |
242 |
243 |
244 |
245 |
246 |
247 |
248 |
249 |
250 |
251 |
252 |

Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | c2eo6A_ |
|  | 99.9 | 31 | PDB header:signaling protein Chain: A: PDB Molecule:b-cell linker protein; PDBTitle: solution structure of the sh2 domain from mouse b-cell2 linker protein blnk
2 | c2hdxB_ |
|  | 99.8 | 27 | PDB header:signaling protein Chain: B: PDB Molecule:sh2-b ph domain containing signaling mediator 1 PDBTitle: crystal structure of the src homology-2 domain of sh2-b in2 complex with jak2 ptyr813 phosphopeptide
3 | c2eo3A_ |
|  | 99.8 | 27 | PDB header:signaling protein Chain: A: PDB Molecule:crk-like protein; PDBTitle: solution structure of the sh2 domain from human crk-like2 protein
4 | c3hizB_ |
|  | 99.8 | 29 | PDB header:transferase/oncoprotein Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit PDBTitle: crystal structure of p110alpha h1047r mutant in complex with2 nish2 of p85alpha
5 | d1mila_ |
|  | 99.8 | 33 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
6 | d2shpa2 |
|  | 99.8 | 27 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
7 | d1fhsa_ |
|  | 99.8 | 29 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
8 | c2gsbA_ |
|  | 99.8 | 30 | PDB header:signaling protein Chain: A: PDB Molecule:ras gtpase-activating protein 1; PDBTitle: solution structure of the second sh2 domain of human ras2 gtpase-activating protein 1
9 | c2hmhA_ |
|  | 99.8 | 24 | PDB header:cytokine regulator Chain: A: PDB Molecule:suppressor of cytokine signaling 3; PDBTitle: crystal structure of socs3 in complex with gp130(ptyr757)2 phosphopeptide.
10 | c2eobA_ |
|  | 99.8 | 28 | PDB header:hydrolase Chain: A: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate PDBTitle: solution structure of the second sh2 domain from rat plc2 gamma-2
11 | c3gqiB_ |
|  | 99.8 | 28 | PDB header:transferase/transferase inhibitor Chain: B: PDB Molecule:phospholipase c-gamma-1; PDBTitle: crystal structure of activated receptor tyrosine kinase in complex2 with substrates
12 | c2kk6A_ |
|  | 99.8 | 33 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fer; PDBTitle: solution structure of sh2 domain of proto-oncogene tyrosine-2 protein kinase fer from homo sapiens, northeast structural3 genomics consortium (nesg) target hr3461d
13 | d1pica_ |
|  | 99.8 | 26 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
14 | d1qada_ |
|  | 99.8 | 27 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
15 | c2vifA_ |
|  | 99.8 | 35 | PDB header:signaling protein Chain: A: PDB Molecule:suppressor of cytokine signalling 6; PDBTitle: crystal structure of socs6 sh2 domain in complex with a c-kit2 phosphopeptide
16 | c2crhA_ |
|  | 99.8 | 26 | PDB header:signaling protein Chain: A: PDB Molecule:vav proto-oncogene; PDBTitle: solution structure of the sh2 domain of human proto-2 oncogene protein vav1
17 | d3c7ia1 |
|  | 99.8 | 28 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
18 | d1a81e2 |
|  | 99.8 | 27 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
19 | c2dlzA_ |
|  | 99.8 | 17 | PDB header:signaling protein Chain: A: PDB Molecule:protein vav-2; PDBTitle: solution structure of the sh2 domain of human protein vav-2
20 | c2lqnA_ |
|  | 99.8 | 25 | PDB header:signaling protein Chain: A: PDB Molecule:crk-like protein; PDBTitle: solution structure of crkl
21 | c1x6cA_ |
| not modelled | 99.8 | 26 | PDB header:signaling protein Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type PDBTitle: solution structures of the sh2 domain of human protein-2 tyrosine phosphatase shp-1
22 | c2c9wA_ |
| not modelled | 99.8 | 27 | PDB header:transcription regulation Chain: A: PDB Molecule:suppressor of cytokine signaling 2; PDBTitle: crystal structure of socs-2 in complex with elongin-b and2 elongin-c at 1.9a resolution
23 | d1r1qa_ |
| not modelled | 99.8 | 23 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
24 | d1ayaa_ |
| not modelled | 99.7 | 27 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
25 | d1luia_ |
| not modelled | 99.7 | 27 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
26 | c2ci8A_ |
| not modelled | 99.7 | 36 | PDB header:translation Chain: A: PDB Molecule:cytoplasmic protein nck1; PDBTitle: sh2 domain of human nck1 adaptor protein - uncomplexed
27 | d2shpa3 |
| not modelled | 99.7 | 29 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
28 | c2dcrA_ |
| not modelled | 99.7 | 34 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps; PDBTitle: fully automated solution structure determination of the fes2 sh2 domain
29 | d2oq1a1 |
| not modelled | 99.7 | 27 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
30 | d1k9aa2 |
| not modelled | 99.7 | 30 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
31 | c2dlyA_ |
| not modelled | 99.7 | 33 | PDB header:transferase Chain: A: PDB Molecule:fyn-related kinase; PDBTitle: solution structure of the sh2 domain of murine fyn-related2 kinase
32 | c2izvA_ |
| not modelled | 99.7 | 19 | PDB header:transcription Chain: A: PDB Molecule:suppressor of cytokine signaling 4; PDBTitle: crystal structure of socs-4 in complex with elongin-b and2 elongin-c at 2.55a resolution
33 | c2lctA_ |
| not modelled | 99.7 | 26 | PDB header:signaling protein Chain: A: PDB Molecule:proto-oncogene vav; PDBTitle: solution structure of the vav1 sh2 domain complexed with a syk-derived2 doubly phosphorylated peptide
34 | d1fu6a_ |
| not modelled | 99.7 | 27 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
35 | d1csya_ |
| not modelled | 99.7 | 27 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
36 | c2fo0A_ |
| not modelled | 99.7 | 33 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform); PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
37 | d1jwoa_ |
| not modelled | 99.7 | 26 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
38 | c1k9aB_ |
| not modelled | 99.7 | 27 | PDB header:transferase Chain: B: PDB Molecule:carboxyl-terminal src kinase; PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution
39 | d1lkka_ |
| not modelled | 99.7 | 30 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
40 | d2eyva1 |
| not modelled | 99.7 | 33 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
41 | c1ka6A_ |
| not modelled | 99.7 | 27 | PDB header:immune system Chain: A: PDB Molecule:sh2 domain protein 1a; PDBTitle: sap/sh2d1a bound to peptide n-py
42 | c2knoA_ |
| not modelled | 99.7 | 29 | PDB header:hydrolase Chain: A: PDB Molecule:tensin-like c1 domain-containing phosphatase; PDBTitle: nmr solution structure of sh2 domain of the human tensin like c12 domain containing phosphatase (tenc1)
43 | c2y3aB_ |
| not modelled | 99.7 | 27 | PDB header:transferase Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit beta; PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941
44 | d1a81a1 |
| not modelled | 99.7 | 22 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
45 | d1opka2 |
| not modelled | 99.7 | 32 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
46 | d2izva2 |
| not modelled | 99.7 | 19 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
47 | d1a81e1 |
| not modelled | 99.7 | 22 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
48 | d2oq1a2 |
| not modelled | 99.7 | 32 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
49 | c2oq1A_ |
| not modelled | 99.7 | 28 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase zap-70; PDBTitle: tandem sh2 domains of zap-70 with 19-mer zeta1 peptide
50 | d1a81a2 |
| not modelled | 99.7 | 26 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
51 | c2shpA_ |
| not modelled | 99.7 | 26 | PDB header:tyrosine phosphatase Chain: A: PDB Molecule:shp-2; PDBTitle: tyrosine phosphatase shp-2
52 | c2el8A_ |
| not modelled | 99.7 | 16 | PDB header:signaling protein Chain: A: PDB Molecule:signal-transducing adaptor protein 2; PDBTitle: solution structure of the human stap2 sh2 domain
53 | c2ekxA_ |
| not modelled | 99.7 | 31 | PDB header:signaling protein Chain: A: PDB Molecule:cytoplasmic tyrosine-protein kinase bmx; PDBTitle: solution structure of the human bmx sh2 domain
54 | d1d4ta_ |
| not modelled | 99.7 | 27 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
55 | d1blja_ |
| not modelled | 99.7 | 30 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
56 | d1rjaa_ |
| not modelled | 99.7 | 29 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
57 | d2cs0a1 |
| not modelled | 99.7 | 26 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
58 | d2c9wa2 |
| not modelled | 99.7 | 28 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
59 | d1nrva_ |
| not modelled | 99.7 | 23 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
60 | d1g83a2 |
| not modelled | 99.7 | 29 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
61 | c2ysxA_ |
| not modelled | 99.7 | 34 | PDB header:signaling protein Chain: A: PDB Molecule:signaling inositol polyphosphate phosphatase PDBTitle: solution structure of the human ship sh2 domain
62 | c2ablA_ |
| not modelled | 99.7 | 32 | PDB header:transferase Chain: A: PDB Molecule:abl tyrosine kinase; PDBTitle: sh3-sh2 domain fragment of human bcr-abl tyrosine kinase
63 | d2fcia1 |
| not modelled | 99.7 | 28 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
64 | c2ge9A_ |
| not modelled | 99.7 | 32 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: solution structures of the sh2 domain of bruton's tyrosine2 kinase
65 | d1f2fa_ |
| not modelled | 99.7 | 27 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
66 | d1i3za_ |
| not modelled | 99.7 | 26 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
67 | d1qcfa2 |
| not modelled | 99.7 | 30 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
68 | d1jyra_ |
| not modelled | 99.7 | 30 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
69 | c2augB_ |
| not modelled | 99.7 | 25 | PDB header:signaling protein Chain: B: PDB Molecule:growth factor receptor-bound protein 14; PDBTitle: crystal structure of the grb14 sh2 domain
70 | d1bkla_ |
| not modelled | 99.7 | 27 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
71 | d1xa6a2 |
| not modelled | 99.7 | 19 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
72 | c1x27F_ |
| not modelled | 99.7 | 29 | PDB header:signaling protein Chain: F: PDB Molecule:proto-oncogene tyrosine-protein kinase lck; PDBTitle: crystal structure of lck sh2-sh3 with sh2 binding site of2 p130cas
73 | c3mazA_ |
| not modelled | 99.7 | 19 | PDB header:signaling protein Chain: A: PDB Molecule:signal-transducing adaptor protein 1; PDBTitle: crystal structure of the human brdg1/stap-1 sh2 domain in complex with2 the ntal ptyr136 peptide
74 | c1y57A_ |
| not modelled | 99.7 | 28 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
75 | d1o48a_ |
| not modelled | 99.7 | 29 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
76 | c2h8hA_ |
| not modelled | 99.7 | 28 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: src kinase in complex with a quinazoline inhibitor
77 | c1oplA_ |
| not modelled | 99.6 | 33 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase; PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
78 | d1rpya_ |
| not modelled | 99.6 | 26 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
79 | c2b3oA_ |
| not modelled | 99.6 | 25 | PDB header:hydrolase Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type PDBTitle: crystal structure of human tyrosine phosphatase shp-1
80 | c1rqqC_ |
| not modelled | 99.6 | 29 | PDB header:transferase/signaling protein Chain: C: PDB Molecule:adaptor protein aps; PDBTitle: crystal structure of the insulin receptor kinase in complex2 with the sh2 domain of aps
81 | c3nhnA_ |
| not modelled | 99.6 | 30 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: crystal structure of the src-family kinase hck sh3-sh2-linker2 regulatory region
82 | d1cwea_ |
| not modelled | 99.6 | 31 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
83 | d2qmsa1 |
| not modelled | 99.6 | 27 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
84 | c2ozoA_ |
| not modelled | 99.6 | 29 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase zap-70; PDBTitle: autoinhibited intact human zap-70
85 | c1a81E_ |
| not modelled | 99.6 | 21 | PDB header:complex (transferase/peptide) Chain: E: PDB Molecule:syk kinase; PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam
86 | c3gxxB_ |
| not modelled | 99.6 | 21 | PDB header:transcription Chain: B: PDB Molecule:transcription elongation factor spt6; PDBTitle: structure of the sh2 domain of the candida glabrata2 transcription elongation factor spt6, crystal form b
87 | c2dm0A_ |
| not modelled | 99.6 | 33 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase txk; PDBTitle: solution structure of the sh2 domain of human tyrosine-2 protein kinase txk
88 | c2eyyA_ |
| not modelled | 99.6 | 27 | PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog PDBTitle: ct10-regulated kinase isoform i
89 | c4fl2A_ |
| not modelled | 99.6 | 24 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase syk; PDBTitle: structural and biophysical characterization of the syk activation2 switch
90 | c2c0iA_ |
| not modelled | 99.6 | 30 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983
91 | c2cr4A_ |
| not modelled | 99.6 | 17 | PDB header:signaling protein Chain: A: PDB Molecule:sh3 domain-binding protein 2; PDBTitle: solution structure of the sh2 domain of human sh3bp2 protein
92 | c2dvjA_ |
| not modelled | 99.6 | 30 | PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog, PDBTitle: phosphorylated crk-ii
93 | c2eyzA_ |
| not modelled | 99.6 | 26 | PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog PDBTitle: ct10-regulated kinase isoform ii
94 | c3ps5A_ |
| not modelled | 99.6 | 28 | PDB header:hydrolase, signaling protein Chain: A: PDB Molecule:tyrosine-protein phosphatase non-receptor type 6; PDBTitle: crystal structure of the full-length human protein tyrosine2 phosphatase shp-1
95 | c1g83A_ |
| not modelled | 99.6 | 32 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fyn; PDBTitle: crystal structure of fyn sh3-sh2
96 | c3qwxX_ |
| not modelled | 99.5 | 29 | PDB header:signaling protein Chain: X: PDB Molecule:cell death abnormality protein 2; PDBTitle: ced-2 1-174
97 | c3qwyA_ |
| not modelled | 99.5 | 29 | PDB header:signaling protein Chain: A: PDB Molecule:cell death abnormality protein 2; PDBTitle: ced-2
98 | d1uura3 |
| not modelled | 99.4 | 21 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
99 | c3or8A_ |
| not modelled | 99.4 | 23 | PDB header:transcription Chain: A: PDB Molecule:transcription elongation factor spt6; PDBTitle: a tandem sh2 domain in transcription elongation factor spt6
100 | c1xa6A_ |
| not modelled | 99.3 | 19 | PDB header:signaling protein Chain: A: PDB Molecule:beta2-chimaerin; PDBTitle: crystal structure of the human beta2-chimaerin
101 | c2xp1A_ |
| not modelled | 99.3 | 28 | PDB header:transcription Chain: A: PDB Molecule:spt6; PDBTitle: structure of the tandem sh2 domains from antonospora locustae2 transcription elongation factor spt6
102 | c2dx0B_ |
| not modelled | 99.3 | 33 | PDB header:hydrolase Chain: B: PDB Molecule:phospholipase c, gamma 2; PDBTitle: crystal structure of the n-terminal sh2 domain of mouse2 phospholipase c-gamma 2
103 | d1bf5a3 |
| not modelled | 99.2 | 21 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
104 | d1bg1a3 |
| not modelled | 99.1 | 19 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
105 | c3cblA_ |
| not modelled | 98.8 | 40 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps; PDBTitle: crystal structure of human feline sarcoma viral oncogene homologue (v-2 fes) in complex with staurosporine and a consensus peptide
106 | c1yvlB_ |
| not modelled | 97.5 | 29 | PDB header:signaling protein Chain: B: PDB Molecule:signal transducer and activator of transcription PDBTitle: structure of unphosphorylated stat1
107 | c1bf5A_ |
| not modelled | 97.3 | 28 | PDB header:gene regulation/dna Chain: A: PDB Molecule:signal transducer and activator of transcription PDBTitle: tyrosine phosphorylated stat-1/dna complex
108 | c1uusA_ |
| not modelled | 97.3 | 24 | PDB header:signal transduction Chain: A: PDB Molecule:stat protein; PDBTitle: structure of an activated dictyostelium stat in its2 dna-unbound form
109 | c2cblA_ |
| not modelled | 96.8 | 22 | PDB header:complex (proto-oncogene/peptide) Chain: A: PDB Molecule:proto-oncogene cbl; PDBTitle: n-terminal domain of cbl in complex with its binding site2 on zap-70
110 | c3bunB_ |
| not modelled | 96.7 | 22 | PDB header:ligase/signaling protein Chain: B: PDB Molecule:e3 ubiquitin-protein ligase cbl; PDBTitle: crystal structure of c-cbl-tkb domain complexed with its2 binding motif in sprouty4
111 | c1y1uA_ |
| not modelled | 96.3 | 23 | PDB header:signaling protein Chain: A: PDB Molecule:signal transducer and activator of transcription 5a; PDBTitle: structure of unphosphorylated stat5a
112 | c1bg1A_ |
| not modelled | 95.9 | 26 | PDB header:transcription/dna Chain: A: PDB Molecule:protein (transcription factor stat3b); PDBTitle: transcription factor stat3b/dna complex
113 | c2vpdA_ |
|  | 95.4 | 28 | PDB header:gene regulation Chain: A: PDB Molecule:pygopus homolog 1; PDBTitle: decoding of methylated histone h3 tail by the pygo-bcl9 wnt2 signaling complex
114 | c3lqiA_ |
|  | 94.7 | 24 | PDB header:transferase Chain: A: PDB Molecule:mll1 phd3-bromo; PDBTitle: crystal structure of mll1 phd3-bromo complexed with h3(1-9)k4me22 peptide
115 | c2kyuA_ |
|  | 94.7 | 20 | PDB header:transferase Chain: A: PDB Molecule:histone-lysine n-methyltransferase mll; PDBTitle: the solution structure of the phd3 finger of mll
116 | c2xb1A_ |
|  | 94.2 | 28 | PDB header:transcription Chain: A: PDB Molecule:pygopus homolog 2, b-cell cll/lymphoma 9-like protein; PDBTitle: crystal structure of the human pygo2 phd finger in complex with the2 b9l hd1 domain
117 | c3cwgA_ |
| not modelled | 93.0 | 30 | PDB header:transcription Chain: A: PDB Molecule:signal transducer and activator of transcription PDBTitle: unphosphorylated mouse stat3 core fragment
118 | d1wepa_ |
| not modelled | 92.1 | 31 | Fold:FYVE/PHD zinc finger Superfamily:FYVE/PHD zinc finger Family:PHD domain
119 | d1weva_ |
| not modelled | 89.5 | 26 | Fold:FYVE/PHD zinc finger Superfamily:FYVE/PHD zinc finger Family:PHD domain
120 | c2f6nA_ |
| not modelled | 88.0 | 22 | PDB header:transcription Chain: A: PDB Molecule:bromodomain phd finger transcription factor; PDBTitle: crystal structure of phd finger-linker-bromodomain fragment2 of human bptf in the free form

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