Email l.a.kelley@imperial.ac.uk Description Q9XYM0 Date Wed Feb 13 11:39:18 GMT 2013 Unique Job ID d6019a9b53fcac1f

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2lqnA_ 100.0 50 PDB header:signaling protein Chain: A: PDB Molecule:crk-like protein; PDBTitle: solution structure of crkl 2 c2eyzA_ 100.0 50 PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog PDBTitle: ct10-regulated kinase isoform ii 3 c3qwyA_ 100.0 37 PDB header:signaling protein Chain: A: PDB Molecule:cell death abnormality protein 2; PDBTitle: ced-2 4 c3qwxX_ 100.0 37 PDB header:signaling protein Chain: X: PDB Molecule:cell death abnormality protein 2; PDBTitle: ced-2 1-174 5 c2dvjA_ 100.0 45 PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog, PDBTitle: phosphorylated crk-ii 6 c2eyyA_ 100.0 51 PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog PDBTitle: ct10-regulated kinase isoform i 7 c2l3sA_ 100.0 48 PDB header:structural protein Chain: A: PDB Molecule:autoinhibited crk protein; PDBTitle: structure of the autoinhibited crk 8 c1griA_ 100.0 29 PDB header:signal transduction adaptor Chain: A: PDB Molecule:growth factor bound protein 2; PDBTitle: grb2 9 c1ng2A_ 100.0 22 PDB header:oxidoreductase activator Chain: A: PDB Molecule:neutrophil cytosolic factor 1; PDBTitle: structure of autoinhibited p47phox 10 c1ov3A_ 100.0 20 PDB header:oxidoreductase activator Chain: A: PDB Molecule:neutrophil cytosol factor 1; PDBTitle: structure of the p22phox-p47phox complex 11 c2eo3A_ 99.9 56 PDB header:signaling protein Chain: A: PDB Molecule:crk-like protein; PDBTitle: solution structure of the sh2 domain from human crk-like2 protein 12 d2oq1a1 99.9 24 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 13 d2eyva1 99.9 55 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 14 c2oq1A_ 99.9 24 PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase zap-70; PDBTitle: tandem sh2 domains of zap-70 with 19-mer zeta1 peptide 15 c2gsbA_ 99.9 23 PDB header:signaling protein Chain: A: PDB Molecule:ras gtpase-activating protein 1; PDBTitle: solution structure of the second sh2 domain of human ras2 gtpase-activating protein 1 16 c2eo6A_ 99.9 25 PDB header:signaling protein Chain: A: PDB Molecule:b-cell linker protein; PDBTitle: solution structure of the sh2 domain from mouse b-cell2 linker protein blnk 17 c3hizB_ 99.9 26 PDB header:transferase/oncoprotein Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit PDBTitle: crystal structure of p110alpha h1047r mutant in complex with2 nish2 of p85alpha 18 c2y3aB_ 99.9 26 PDB header:transferase Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit beta; PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941 19 d1a81a1 99.9 20 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 20 c2b3oA_ 99.9 26 PDB header:hydrolase Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type PDBTitle: crystal structure of human tyrosine phosphatase shp-1 21 d2oq1a2 not modelled 99.9 24 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 22 c2dlyA_ not modelled 99.9 26 PDB header:transferase Chain: A: PDB Molecule:fyn-related kinase; PDBTitle: solution structure of the sh2 domain of murine fyn-related2 kinase 23 d1fhsa_ not modelled 99.9 23 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 24 d3c7ia1 not modelled 99.9 24 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 25 c2hdxB_ not modelled 99.9 22 PDB header:signaling protein Chain: B: PDB Molecule:sh2-b ph domain containing signaling mediator 1 PDBTitle: crystal structure of the src homology-2 domain of sh2-b in2 complex with jak2 ptyr813 phosphopeptide 26 c2fo0A_ not modelled 99.9 20 PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform); PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase 27 c2shpA_ not modelled 99.9 27 PDB header:tyrosine phosphatase Chain: A: PDB Molecule:shp-2; PDBTitle: tyrosine phosphatase shp-2 28 c2ablA_ not modelled 99.9 31 PDB header:transferase Chain: A: PDB Molecule:abl tyrosine kinase; PDBTitle: sh3-sh2 domain fragment of human bcr-abl tyrosine kinase 29 d1blja_ not modelled 99.9 25 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 30 c2augB_ not modelled 99.9 28 PDB header:signaling protein Chain: B: PDB Molecule:growth factor receptor-bound protein 14; PDBTitle: crystal structure of the grb14 sh2 domain 31 d1a81e2 not modelled 99.9 24 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 32 d1a81e1 not modelled 99.9 20 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 33 d1csya_ not modelled 99.9 23 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 34 c2crhA_ not modelled 99.9 25 PDB header:signaling protein Chain: A: PDB Molecule:vav proto-oncogene; PDBTitle: solution structure of the sh2 domain of human proto-2 oncogene protein vav1 35 d1a81a2 not modelled 99.9 24 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 36 c2ozoA_ not modelled 99.9 25 PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase zap-70; PDBTitle: autoinhibited intact human zap-70 37 d2shpa2 not modelled 99.9 26 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 38 d1nrva_ not modelled 99.9 27 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 39 d1pica_ not modelled 99.9 26 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 40 c2eobA_ not modelled 99.9 26 PDB header:hydrolase Chain: A: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate PDBTitle: solution structure of the second sh2 domain from rat plc2 gamma-2 41 d2qmsa1 not modelled 99.9 24 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 42 c1x6cA_ not modelled 99.9 30 PDB header:signaling protein Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type PDBTitle: solution structures of the sh2 domain of human protein-2 tyrosine phosphatase shp-1 43 d1rjaa_ not modelled 99.9 30 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 44 c4fl2A_ not modelled 99.9 21 PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase syk; PDBTitle: structural and biophysical characterization of the syk activation2 switch 45 c1ka6A_ not modelled 99.9 22 PDB header:immune system Chain: A: PDB Molecule:sh2 domain protein 1a; PDBTitle: sap/sh2d1a bound to peptide n-py 46 c3gqiB_ not modelled 99.9 26 PDB header:transferase/transferase inhibitor Chain: B: PDB Molecule:phospholipase c-gamma-1; PDBTitle: crystal structure of activated receptor tyrosine kinase in complex2 with substrates 47 c1x27F_ not modelled 99.9 27 PDB header:signaling protein Chain: F: PDB Molecule:proto-oncogene tyrosine-protein kinase lck; PDBTitle: crystal structure of lck sh2-sh3 with sh2 binding site of2 p130cas 48 d1luia_ not modelled 99.9 26 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 49 c1y57A_ not modelled 99.9 25 PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor 50 d2izva2 not modelled 99.9 22 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 51 d1d4ta_ not modelled 99.9 23 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 52 d1opka2 not modelled 99.9 32 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 53 d1jyra_ not modelled 99.9 27 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 54 c2dlzA_ not modelled 99.9 24 PDB header:signaling protein Chain: A: PDB Molecule:protein vav-2; PDBTitle: solution structure of the sh2 domain of human protein vav-2 55 d1lkka_ not modelled 99.9 32 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 56 c1k9aB_ not modelled 99.9 24 PDB header:transferase Chain: B: PDB Molecule:carboxyl-terminal src kinase; PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution 57 c2ysxA_ not modelled 99.9 33 PDB header:signaling protein Chain: A: PDB Molecule:signaling inositol polyphosphate phosphatase PDBTitle: solution structure of the human ship sh2 domain 58 c2ci8A_ not modelled 99.9 24 PDB header:translation Chain: A: PDB Molecule:cytoplasmic protein nck1; PDBTitle: sh2 domain of human nck1 adaptor protein - uncomplexed 59 c1oplA_ not modelled 99.9 21 PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase; PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase 60 c2ge9A_ not modelled 99.9 26 PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: solution structures of the sh2 domain of bruton's tyrosine2 kinase 61 d1g83a2 not modelled 99.9 31 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 62 d1o48a_ not modelled 99.9 31 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 63 c2vifA_ not modelled 99.9 17 PDB header:signaling protein Chain: A: PDB Molecule:suppressor of cytokine signalling 6; PDBTitle: crystal structure of socs6 sh2 domain in complex with a c-kit2 phosphopeptide 64 d1r1qa_ not modelled 99.9 24 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 65 c3ps5A_ not modelled 99.9 29 PDB header:hydrolase, signaling protein Chain: A: PDB Molecule:tyrosine-protein phosphatase non-receptor type 6; PDBTitle: crystal structure of the full-length human protein tyrosine2 phosphatase shp-1 66 d1jwoa_ not modelled 99.9 32 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 67 c2c9wA_ not modelled 99.9 24 PDB header:transcription regulation Chain: A: PDB Molecule:suppressor of cytokine signaling 2; PDBTitle: crystal structure of socs-2 in complex with elongin-b and2 elongin-c at 1.9a resolution 68 d1k9aa2 not modelled 99.9 31 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 69 d1bkla_ not modelled 99.9 31 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 70 c3nhnA_ not modelled 99.9 29 PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: crystal structure of the src-family kinase hck sh3-sh2-linker2 regulatory region 71 d2shpa3 not modelled 99.9 38 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 72 c2h8hA_ not modelled 99.9 25 PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: src kinase in complex with a quinazoline inhibitor 73 d1i3za_ not modelled 99.9 26 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 74 c2c0iA_ not modelled 99.9 25 PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983 75 c2lctA_ not modelled 99.9 23 PDB header:signaling protein Chain: A: PDB Molecule:proto-oncogene vav; PDBTitle: solution structure of the vav1 sh2 domain complexed with a syk-derived2 doubly phosphorylated peptide 76 c2knoA_ not modelled 99.9 24 PDB header:hydrolase Chain: A: PDB Molecule:tensin-like c1 domain-containing phosphatase; PDBTitle: nmr solution structure of sh2 domain of the human tensin like c12 domain containing phosphatase (tenc1) 77 d1qcfa2 not modelled 99.9 28 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 78 d1ayaa_ not modelled 99.9 27 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 79 c2izvA_ not modelled 99.9 17 PDB header:transcription Chain: A: PDB Molecule:suppressor of cytokine signaling 4; PDBTitle: crystal structure of socs-4 in complex with elongin-b and2 elongin-c at 2.55a resolution 80 d1f2fa_ not modelled 99.9 31 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 81 c1a81E_ not modelled 99.9 24 PDB header:complex (transferase/peptide) Chain: E: PDB Molecule:syk kinase; PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam 82 c2kk6A_ not modelled 99.9 29 PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fer; PDBTitle: solution structure of sh2 domain of proto-oncogene tyrosine-2 protein kinase fer from homo sapiens, northeast structural3 genomics consortium (nesg) target hr3461d 83 c2ekxA_ not modelled 99.9 26 PDB header:signaling protein Chain: A: PDB Molecule:cytoplasmic tyrosine-protein kinase bmx; PDBTitle: solution structure of the human bmx sh2 domain 84 d1fu6a_ not modelled 99.9 26 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 85 d1rpya_ not modelled 99.9 22 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 86 c2hmhA_ not modelled 99.9 23 PDB header:cytokine regulator Chain: A: PDB Molecule:suppressor of cytokine signaling 3; PDBTitle: crystal structure of socs3 in complex with gp130(ptyr757)2 phosphopeptide. 87 d2c9wa2 not modelled 99.9 25 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 88 d2fcia1 not modelled 99.9 26 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 89 d1mila_ not modelled 99.9 26 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 90 c2el8A_ not modelled 99.9 22 PDB header:signaling protein Chain: A: PDB Molecule:signal-transducing adaptor protein 2; PDBTitle: solution structure of the human stap2 sh2 domain 91 d2cs0a1 not modelled 99.9 23 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 92 d1qada_ not modelled 99.9 26 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 93 c2dcrA_ not modelled 99.9 28 PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps; PDBTitle: fully automated solution structure determination of the fes2 sh2 domain 94 d1cwea_ not modelled 99.9 35 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 95 c1g83A_ not modelled 99.9 31 PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fyn; PDBTitle: crystal structure of fyn sh3-sh2 96 c1mv3A_ not modelled 99.9 20 PDB header:endocytosis/exocytosis Chain: A: PDB Molecule:myc box dependent interacting protein 1; PDBTitle: nmr structure of the tumor suppressor bin1: alternative2 splicing in melanoma and interaction with c-myc 97 c3mazA_ not modelled 99.9 20 PDB header:signaling protein Chain: A: PDB Molecule:signal-transducing adaptor protein 1; PDBTitle: crystal structure of the human brdg1/stap-1 sh2 domain in complex with2 the ntal ptyr136 peptide 98 c1rqqC_ not modelled 99.9 19 PDB header:transferase/signaling protein Chain: C: PDB Molecule:adaptor protein aps; PDBTitle: crystal structure of the insulin receptor kinase in complex2 with the sh2 domain of aps 99 c3gxxB_ not modelled 99.9 19 PDB header:transcription Chain: B: PDB Molecule:transcription elongation factor spt6; PDBTitle: structure of the sh2 domain of the candida glabrata2 transcription elongation factor spt6, crystal form b 100 d1udla_ not modelled 99.9 24 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 101 c2dm0A_ not modelled 99.8 25 PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase txk; PDBTitle: solution structure of the sh2 domain of human tyrosine-2 protein kinase txk 102 d1xa6a2 not modelled 99.8 24 Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain 103 c2dbkA_ not modelled 99.8 50 PDB header:signaling protein Chain: A: PDB Molecule:crk-like protein; PDBTitle: solution structures of the sh3 domain of human crk-like2 protein 104 c2cr4A_ not modelled 99.8 22 PDB header:signaling protein Chain: A: PDB Molecule:sh3 domain-binding protein 2; PDBTitle: solution structure of the sh2 domain of human sh3bp2 protein 105 c2dx0B_ not modelled 99.8 25 PDB header:hydrolase Chain: B: PDB Molecule:phospholipase c, gamma 2; PDBTitle: crystal structure of the n-terminal sh2 domain of mouse2 phospholipase c-gamma 2 106 c2dx1A_ not modelled 99.8 22 PDB header:signaling protein Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 4; PDBTitle: crystal structure of rhogef protein asef 107 c2dybA_ not modelled 99.8 17 PDB header:oxidoreductase Chain: A: PDB Molecule:neutrophil cytosol factor 4; PDBTitle: the crystal structure of human p40(phox) 108 c2ed0A_ not modelled 99.8 25 PDB header:signaling protein Chain: A: PDB Molecule:abl interactor 2; PDBTitle: solution structure of the sh3 domain of abl interactor 22 (abelson interactor 2) 109 c3jv3A_ not modelled 99.8 26 PDB header:protein binding Chain: A: PDB Molecule:intersectin-1; PDBTitle: structure of sh3e-dh unit of murine intersectin-1l 110 d1ng2a2 not modelled 99.8 15 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 111 c3nmzD_ not modelled 99.8 18 PDB header:cell adhesion/cell cycle Chain: D: PDB Molecule:rho guanine nucleotide exchange factor 4; PDBTitle: crytal structure of apc complexed with asef 112 c2ebpA_ not modelled 99.8 34 PDB header:cell adhesion Chain: A: PDB Molecule:sam and sh3 domain-containing protein 1; PDBTitle: solution structure of the sh3 domain from human sam and sh32 domain containing protein 1 113 c2cubA_ not modelled 99.8 22 PDB header:signaling protein Chain: A: PDB Molecule:cytoplasmic protein nck1; PDBTitle: solution structure of the sh3 domain of the human2 cytoplasmic protein nck1 114 c2eyxA_ not modelled 99.8 64 PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog PDBTitle: c-terminal sh3 domain of ct10-regulated kinase 115 c1x2qA_ not modelled 99.8 19 PDB header:signaling protein Chain: A: PDB Molecule:signal transducing adapter molecule 2; PDBTitle: solution structure of the sh3 domain of the signal2 transducing adaptor molecule 2 116 c2yuoA_ not modelled 99.8 29 PDB header:signaling protein Chain: A: PDB Molecule:run and tbc1 domain containing 3; PDBTitle: solution structure of the sh3 domain of mouse run and tbc12 domain containing 3 117 c2bzxA_ not modelled 99.8 67 PDB header:sh3 domain Chain: A: PDB Molecule:crk-like protein; PDBTitle: atomic model of crkl-sh3c monomer 118 c2djqA_ not modelled 99.7 24 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:sh3 domain containing ring finger 2; PDBTitle: the solution structure of the first sh3 domain of mouse sh32 domain containing ring finger 2 119 c2dlpA_ not modelled 99.7 22 PDB header:structural protein Chain: A: PDB Molecule:kiaa1783 protein; PDBTitle: solution structure of the sh3 domain of human kiaa17832 protein 120 c2oi3A_ not modelled 99.7 16 PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: nmr structure analysis of the hematopoetic cell kinase sh32 domain complexed with an artificial high affinity ligand3 (pd1)