Job Description Q8INJ8 Confidence 100.00% Date Wed Feb 13 11:35:57 GMT 2013 Rank 97 Aligned Residues 255 % Identity 34% Template c3v5qB_ PDB info PDB header:transferase/transferase inhibitor Chain: B: PDB Molecule:nt-3 growth factor receptor; PDBTitle: discovery of a selective trk inhibitor with efficacy in rodent cancer2 tumor models Resolution 2.20 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		793	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.		.	.	.	.	.	.	.	.	820			.	.	.	.	.	.	.	.	.	830			.	.	.	.	.	.	.	.	.	840	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.
Predicted Secondary structure																					.										.	.											.	.
Query SS confidence																					.										.	.											.	.
Query Sequence		W	V	I	P	E	A	E	L	Q	L	R	E	S	I	G	K	G	E	F	.	G	D	V	M	L	G	I	L	R	.	.	N	E	K	V	A	V	K	M	L	K	.	.	D	E	G	A	V	Q	K	F	L	A	E	A	S	V	M	T	T	L	E	H	D	N	L	V	K	F	I	G	L	V	F	T	S	K	H	L	Y
Query Conservation																					.										.	.											.	.
Alig confidence																					.										.	.											.	.																																		.	.
Template Conservation																																																																														.	.
Template Sequence		Q	H	I	K	R	R	D	I	V	L	K	R	E	L	G	F	K	V	F	L	A	E	C	Y	N	L	S	P	T	K	D	K	M	L	V	A	V	K	A	L	K	D	P	T	L	A	A	R	K	D	F	Q	R	E	A	E	L	L	T	N	L	Q	H	E	H	I	V	K	F	Y	G	V	C	G	D	P	.	.	L	I
Template Known Secondary structure						G	G	G																		S			S	S	S	S											S																						T	T	B											.	.
Template Predicted Secondary structure																																																																														.	.
Template SS confidence
		531	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.			.	.
		868	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	V	T	E	Y	M	S	K	G	S	L	V	D	Y	L	R	S	R	G	R	Q	H	I	T	K	K	D	Q	I	I	F	A	Y	D	T	A	S	G	M	E	Y	L	E	A	K	K	V	V	H	R	D	L	A	A	R	N	V	L	I	S	E	D	C	V	A	K	V	S	D	F	G	L	A	R	E	E	C	Y	N	L
Query Conservation
Alig confidence																							.																																																				.
Template Conservation																							.																																																				.
Template Sequence		M	V	F	E	Y	M	K	H	G	D	L	N	K	F	L	R	A	H	G	P	E	.	L	G	L	S	Q	M	L	H	I	A	S	Q	I	A	S	G	M	V	Y	L	A	S	Q	H	F	V	H	R	D	L	A	T	R	N	C	L	V	G	A	N	L	L	V	K	I	G	D	F	G	M	D	.	V	Y	S	T	D	Y
Template Known Secondary structure								T	T									T	T				.																							T	T				S			S	G	G	G					G	G	G											.		S	G	G	G
Template Predicted Secondary structure																							.																																																				.
Template SS confidence
		615	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.		.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.		.	.	.	690	.	.
		948	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	V	G	K	L	P	I	K	W	T	A	P	E	A	L	K	N	G	R	F	S	N	K	S	D	M	W	S	F	G	I	L	L	W	E	I	Y	S	F	G	R	V	P	Y	P	R	I	P	L	A	D	V	V	K	H	V	E	V	G	Y	K	M	E	A	P	E	G	C	P	P	E	I	Y	E	M	M	R	Q	A	W
Query Conservation
Alig confidence
Template Conservation
Template Sequence		Y	R	T	M	L	P	I	R	W	M	P	P	E	S	I	M	Y	R	K	F	T	T	E	S	D	V	W	S	F	G	V	I	L	W	E	I	F	T	Y	G	K	Q	P	W	F	Q	L	S	N	T	E	V	I	E	C	I	T	Q	G	R	V	L	E	R	P	R	V	C	P	K	E	V	Y	D	V	M	L	G	C	W
Template Known Secondary structure		B				B		G	G	G																												T	T	T	S			T	T	T	T	S												T							T	T
Template Predicted Secondary structure
Template SS confidence
		710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.
		1028	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	L	N	P	A	K	R	P	T	F	A	E	L	K	V	K	L	Q	L	L	N	N	A	T
Query Conservation
Alig confidence
Template Conservation
Template Sequence		Q	R	E	P	Q	Q	R	L	N	I	K	E	I	Y	K	I	L	H	A	L	G	K	A	T
Template Known Secondary structure			S	S	G	G	G	S																T
Template Predicted Secondary structure
Template SS confidence
		808	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions