Return to main results Retrieve Phyre Job Id

Job DescriptionQ8INJ8
Confidence100.00%DateWed Feb 13 11:35:57 GMT 2013
Rank2Aligned Residues368
% Identity41%Templatec1oplA_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase; PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
Resolution3.42 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   678.680.........690.........700.........710.........720.........730... ......740.........750......
Predicted Secondary structure 



































.













Query SS confidence 























































.






















Query Sequence  KLNAMPWFHGSITRDEAEHLLQPREDGLFLVRESTNFPGDYTLCVCFQSKVEHYRV. KYLENKLTIDDEEYFENLGQLVA
Query Conservation                                                          .                       
Alig confidence 























































.






















Template Conservation   
    

 
 
 
  

  
     
 



 
    
   


     
 
  
     
         
 

  

 
Template Sequence  SLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVH
Template Known Secondary structure  SGGGSTT

GGG

TT
SSSTT
TT

TTS
SSTTS
BSS
Template Predicted Secondary structure 









































Template SS confidence 















































































   140.........150.........160.........170.........180.........190.........200.........210.........
 
   757..760.........770.........780.........790.........800.........810.........820 .........830 ...
Predicted Secondary structure 






































..

.
Query SS confidence 































































. .









.


Query Sequence  HYEADADGLCTQLIKCLPKLGKQEFCINSKDFVDKGWVIPEAELQLRESIGKGEFGDVMLGILR. . NEKVAVKMLK. DEG
Query Conservation                                                    
 
  
 
      ..    
 
   .   
Alig confidence 





























..































..









.


Template Conservation   
     

   
  
              ..     

      
   

 
 

 
           



 

    
Template Sequence  HHSTVADGLITTLHYPAPKRNKPTVYGVSP. . NYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTM
Template Known Secondary structure  TT

TTSSS






S



SSS
S..SSS

B

GGGSGGGTTSSGGGT

SSSS
Template Predicted Secondary structure 



























..






















Template SS confidence 















































































   220.........230.........240......... 250.........260.........270.........280.........290.......
 
   834.....840.........850.........860.........870.........880.........890.........900.........910...
Predicted Secondary structure 





















Query SS confidence 















































































Query Sequence  AVQKFLAEASVMTTLEHDNLVKFIGLVFTSKHLYLVTEYMSKGSLVDYLRSRGRQHITKKDQIIFAYDTASGMEYLEAKK
Query Conservation         
        
  
                 
      
                              

   
Alig confidence 















































































Template Conservation      
  
  

  
 
 


 
 
         




   


   
                  

  

 


   
Template Sequence  EVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKN
Template Known Secondary structure 



TTB


SSSS


TT
BS
TTTS
TT
Template Predicted Secondary structure 
























Template SS confidence 















































































   298.300.........310.........320.........330.........340.........350.........360.........370.......
 
   914.....920.........930.........940.........950. ........960.........970.........980.........
Predicted Secondary structure 

























....












Query SS confidence 





































. . . .





































Query Sequence  VVHRDLAARNVLISEDCVAKVSDFGLAREECYNLDVGK. . . . LPIKWTAPEALKNGRFSNKSDMWSFGILLWEIYSFGRV
Query Conservation    
 
 
  
 
       
  


             ....       

           
  
 
    
       
Alig confidence 





































....





































Template Conservation   




   


       

 




                     


       
 








 
 

 
 
  
Template Sequence  FIHRNLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMS
Template Known Secondary structure 
S

SGGG
GGG


TT


TT



TT



GGG



TTS

Template Predicted Secondary structure 





































Template SS confidence 















































































   378.380.........390.........400.........410.........420.........430.........440.........450.......
 
   990.........1000.........1010.........1020.........1030.........1040.......
Predicted Secondary structure 























Query SS confidence 

























































Query Sequence  PYPRIPLADVVKHVEVGYKMEAPEGCPPEIYEMMRQAWDLNPAKRPTFAELKVKLQLL
Query Conservation 
                                        
  

        
   
Alig confidence 

























































Template Conservation 
            
  
 
   
   
  
  

  
   

  


   
   
   
Template Sequence  PYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETM
Template Known Secondary structure  SSTT

TTTTT





TT

T
SSGGGS

TS
Template Predicted Secondary structure 
























Template SS confidence 

























































   458.460.........470.........480.........490.........500.........510.....
 
Download:Text version FASTA pairwise alignment 3D Model in PDB format

View in Jmol

Send structure to FirstGlance for more viewing options


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions