Job Description P29349 Confidence 100.00% Date Tue Jan 22 11:46:53 GMT 2013 Rank 41 Aligned Residues 267 % Identity 31% Template c4az1B_ PDB info PDB header:hydrolase Chain: B: PDB Molecule:tyrosine specific protein phosphatase; PDBTitle: crystal structure of the trypanosoma cruzi protein tyrosine2 phosphatase tcptp1, a potential therapeutic target for chagas'3 disease Resolution 2.18 Å

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		219	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	E	Q	L	V	K	G	G	F	W	E	E	F	E	S	L	Q	Q	D	S	R	D	T	F	S	R	N	E	G	Y	K	Q	E	N	R	L	K	N	R	Y	R	N	I	L	P	Y	D	H	T	R	V	K	L	L	D	V	E	H	S	V	A	G	A	E	Y	I	N	A	N	Y	I	R	L	P	T	D	G	D	L	Y
Query Conservation
Alig confidence																									.																																																.	.	.
Template Conservation																									.																																																.	.	.
Template Sequence		S	V	Q	A	Q	Y	E	R	V	Q	R	E	F	S	L	L	L	R	Q	E	D	P	R	.	S	I	S	F	A	T	S	L	K	N	R	H	K	N	R	Y	L	D	I	L	A	N	E	A	T	L	Y	P	Q	V	T	D	A	P	G	A	S	T	P	Y	Y	I	N	G	N	L	I	.	.	.	D	L	D	L	P	H
Template Known Secondary structure																		T	T	S			G	G	.	G									T	G	G	G		S		T	T					T	T	T	B	T	T	G	G	G			S	S				S				S					.	.	.			S	S	S
Template Predicted Secondary structure																									.																																																.	.	.
Template SS confidence
		13	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.		.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.				.	.	.	.	.	.
		299	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		N	M	S	S	S	S	E	S	L	N	S	S	V	P	S	C	P	A	C	T	A	A	Q	T	Q	R	N	C	S	N	C	Q	L	Q	N	K	T	C	V	Q	C	A	V	K	S	A	I	L	P	Y	S	N	C	A	T	C	S	R	K	S	D	S	L	S	K	H	K	R	S	E	S	S	A	S	S	S	P	S	S	G
Query Conservation
Alig confidence												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		K	F	V	A	C	Q	A	P	V	V	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure											G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		89	90	.	.	.	.	.	.	.	.
		379	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	G	S	G	P	G	S	S	G	T	S	G	V	S	S	V	N	G	P	G	T	P	T	N	L	T	S	G	T	A	G	C	L	V	G	L	L	K	R	H	S	N	D	S	S	G	A	V	S	I	S	M	A	E	R	E	R	E	R	E	R	E	M	F	K	T	Y	I	A	T	Q	G	C	L	L	T	Q	Q	V	N
Query Conservation
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	Q
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
																																																																																	99
		459	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.				500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.								520	.	.	.	.	.	.	.	.
Predicted Secondary structure																																											.	.	.																					.	.	.	.	.	.	.
Query SS confidence																																											.	.	.																					.	.	.	.	.	.	.
Query Sequence		T	V	T	D	F	W	N	M	V	W	Q	E	N	T	R	V	I	V	M	T	T	K	E	Y	E	R	G	K	E	K	C	A	R	Y	W	P	D	E	G	R	S	.	.	.	E	Q	F	G	H	A	R	I	Q	C	V	S	E	N	S	T	S	D	Y	T	.	.	.	.	.	.	.	L	R	E	F	L	V	S	W	R
Query Conservation																																											.	.	.																					.	.	.	.	.	.	.
Alig confidence																																											.	.	.																					.	.	.	.	.	.	.
Template Conservation
Template Sequence		G	I	P	D	F	L	A	M	L	Y	E	K	K	I	S	L	V	I	M	V	T	K	L	E	E	G	G	F	V	K	A	D	R	Y	W	P	E	E	R	G	S	G	S	I	A	V	S	G	N	C	G	L	T	I	S	E	D	P	G	K	A	Y	E	V	E	D	E	L	K	I	T	R	R	Y	L	I	L	Q	R	A
Template Known Secondary structure		G											T	T								S		S			T	T								S			S	S	S							S	S	S	S								T	T	S						T	T	T	T											T
Template Predicted Secondary structure
Template SS confidence
		100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.
		529	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	Q	P	A	R	R	I	F	H	Y	H	F	Q	V	W	P	D	H	G	V	P	A	D	P	G	C	V	L	N	F	L	Q	D	V	N	T	R	Q	S	H	L	A	Q	A	G	E	K	P	G	P	I	C	V	H	C	S	A	G	I	G	R	T	G	T	F	I	V	I	D	M	I	L	D	Q	I	V	R	N	G	L
Query Conservation
Alig confidence																																						.	.	.	.	.	.	.	.																																				.
Template Conservation																																						.	.	.	.	.	.	.	.																																				.
Template Sequence		D	E	P	P	H	K	F	T	Q	V	Q	Y	T	G	W	P	D	H	G	I	P	Q	S	A	T	S	L	E	A	L	L	T	N	V	K	N	.	.	.	.	.	.	.	.	S	P	T	T	V	P	V	V	V	H	C	S	A	G	I	G	R	T	G	T	L	I	G	A	Y	A	A	L	T	H	L	E	R	G	T	.
Template Known Secondary structure		T	S												S			T	T	S			S															.	.	.	.	.	.	.	.	S		S	S	S							S	S	S	S	S																		T		.
Template Predicted Secondary structure																																						.	.	.	.	.	.	.	.																																				.
Template SS confidence
		180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.									.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250
		609	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	T	E	I	D	I	Q	R	T	I	Q	M	V	R	S	Q	R	S	G	L	V	Q	T	E	A	Q	Y	K	F	V	Y	Y	A	V	Q	H	Y	I	Q
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	T	D	T	T	V	Y	D	V	V	S	A	M	R	R	Q	R	F	G	M	V	Q	R	M	E	Q	Y	F	V	I	Y	L	T	L	M	C	R	L	G
Template Known Secondary structure				T	T													S	T	T		S		S													T	T	T	T
Template Predicted Secondary structure
Template SS confidence
		251	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

---

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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions