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Job DescriptionP29349
Confidence100.00%DateTue Jan 22 11:46:53 GMT 2013
Rank4Aligned Residues422
% Identity29%Templatec3sr9A_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:receptor-type tyrosine-protein phosphatase s; PDBTitle: crystal structure of mouse ptpsigma
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   210.........220.. .......230.........240.........250.........260.........270.........280......
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Query Sequence  ITAAGINARVEQL. . . VKGGFWEEFESLQQDSRDTFSRNEGYKQENRLKNRYRNILPYDHTRVKLLDVEHSVAGAEYINA
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Template Sequence  IPITDMAEHMERLKANDSLKLSQEYESIDPG. . QQFTWEHSNLEANKPKNRYANVIAYDHSRVILQPLE. GIMGSDYINA
Template Known Secondary structure  TTS



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STTTGGG
SSTT



GGG



T.T
TTTT
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   1332.......1340.........1350.........1360.. .......1370.........1380.........1390........ .1400........
 
   287..290.........300.........310.........320.........330.........340.....
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Query Sequence  NYIRLPTDGDLYNMSSSSESLNSSVPSCPACTAAQTQRNCSNCQLQNKTCVQCAVKSAI. . . . . . . . . . . . . . . . . . . . .
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Template Sequence  NYVD. . GYRRQNAYIATQGPLPETFGDFWRMVWEQRSATVVMMTRLEEKSRIKCDQYWPNRGTETYGFIQVTLLDTMELA
Template Known Secondary structure  ..TT



GGGTT


S
STTS



S
SSSTT
S
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   14091410.. .......1420.........1430.........1440.........1450.........1460.........1470.........1480......
 
   346...350.........360.........370...... ...380.........390.........400..
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Query Sequence  . . . . . . . LPYSNCATCSRKSDSLSKHKRSESSASSSPS. . . . . . . . . . . . . . . . SGSGSGPGSSGTSGVSSVNGPGTPTN
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Template Sequence  TFCVRTFSLHKNGSSEKREVRHFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLE
Template Known Secondary structure  SSS






SSS

S
SSS
TTS

SSSSSS
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   1487..1490.........1500.........1510.........1520.........1530.........1540.........1550.........1560......
 
   403 ......410.........420..
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Query Sequence  L. . . . . . . . . . . . . . . TSGTAGCLVGLLKRHSNDS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  RIKTEKTVDVYGHVTLMRSQRNYMVQTEDQYGFIHEALLEAVGCGNTEVPARSLYTYIQKLAQVEPGEHVTGMELEFKRL
Template Known Secondary structure  TTSS
TTSTTSS
SS



GGGTS

TT
SS
TT
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   1567..1570.........1580.........1590.........1600.........1610.........1620.........1630.........1640......
 
   423......430.........440.........450.........460.........470
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . SGAVSISMAEREREREREMFKTYIATQGCLLTQQVNTVTDFWNMVWQE
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Template Sequence  AFITASLPCNKFKNRLVNILPYESSRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPL. . . . AETTEDFWRALWEN
Template Known Secondary structure 

TTTS
TT
TTT
S
SSS


TTTB





TT
TT
S

S

SSSTT




....TTTT
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   1647..1650.........1660.........1670.........1680.........1690.........1700........ .1710.........1720..
 
   471........480.........490.........500.........510.........520....... ..530.........540.........
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Query Sequence  NTRVIVMTTKEYERGKEKCARYWPDEGRSEQFGHARIQCVSENSTSDYTLREFLVSW. RDQPARRIFHYHFQVWPDHGVP
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Template Sequence  NSTIVVMLTKLREMGREKCHQYWPAERS. ARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGAP
Template Known Secondary structure  T


S
SB
SSSB
S


S
SSS
.TT
SSTTT



S
SSS

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   1731........1740.........1750........ .1760.........1770.........1780.........1790.........1800.........
 
   550.........560.........570.........580.........590.........600.........610.........620.........
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Query Sequence  ADPGCVLNFLQDVNTRQSHLAQAGEKPGPICVHCSAGIGRTGTFIVIDMILDQIVRNGLDTEIDIQRTIQMVRSQRSGLV
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Template Sequence  KSGEGFIDFIGQVHKTKEQFGQ. . . . DGPISVHCSAGVGRTGVFITLSIVLERMRYEGV. . . VDIFQTVKVLRTQRPAMV
Template Known Secondary structure  S
STT
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SSSSST
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S
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   1810.........1820.........1830. ........1840.........1850.........1860.... .....1870.........1880..
 
   630.........640........
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Query Sequence  QTEAQYKFVYYAVQHYIQT
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Template Sequence  QTEDEYQFCFQAALEYLGS
Template Known Secondary structure 
S
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   1883......1890.........1900.
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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