Return to main results Retrieve Phyre Job Id

Job DescriptionP29349
Confidence100.00%DateTue Jan 22 11:46:53 GMT 2013
Rank19Aligned Residues290
% Identity36%Templatec2vexA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:tyrosine-protein phosphatase non-receptor type 1; PDBTitle: crystal strucutre of protein tyrosine phosphatase 1b in2 complex with an isothiazolidinone-containing inhibitor
Resolution2.20 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   215....220.. .......230.........240.........250.........260.........270.........280.........290...
Predicted Secondary structure 

.














































Query SS confidence 







.






































































Query Sequence  INARVEQL. VKGGFWEEFESLQQDSRDTFSRNEGYKQENRLKNRYRNILPYDHTRVKLLDVEHSVAGAEYINANYIRLPT
Query Conservation          .   

 



 
        
       


 



 











  
    
 









 

Alig confidence 







.


















.




























.....













..
Template Conservation         
        
   
       .         
  


   
 
 
 


 
.....     





 
 .. 
Template Sequence  MEKEFEQIDKSGSWAAIYQDIRHEASDF. PCRVAKLPKNKNRNRYRDVSPFDHSRIKL. . . . . HQEDNDYINASLIK. . M
Template Known Secondary structure 
T
S


.

TTTTSGGGGGG
SSTT



GGG
.....S
SS

..
Template Predicted Secondary structure 









.














.....






..
Template SS confidence 















































































   3......10.........20.........30 .........40.........50......... 60.........70... .
 
   294.....300.........310.........320.........330.........340.........350.........360.........370...
Predicted Secondary structure 























































Query SS confidence 















































































Query Sequence  DGDLYNMSSSSESLNSSVPSCPACTAAQTQRNCSNCQLQNKTCVQCAVKSAILPYSNCATCSRKSDSLSKHKRSESSASS
Query Conservation 
   









  

 








    




   
                     
 
 
 


 


 


 
Alig confidence 














.................................................................
Template Conservation        

 

 
  .................................................................
Template Sequence  EEAQRSYILTQGPLP. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  TTTT



T.................................................................
Template Predicted Secondary structure 







.................................................................
Template SS confidence 















































































   75....80.........
 
   374.....380.........390.........400.........410.........420.........430.........440.........450...
Predicted Secondary structure 
































































Query SS confidence 















































































Query Sequence  SPSSGSGSGPGSSGTSGVSSVNGPGTPTNLTSGTAGCLVGLLKRHSNDSSGAVSISMAEREREREREMFKTYIATQGCLL
Query Conservation   
   
  











 
  
  
        
 

   
       
                 
 







 
Template Conservation  ................................................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ................................................................................
Template Predicted Secondary structure  ................................................................................
Template SS confidence 















































































  
 
   454.....460.........470.........480.........490...... ...500.. .......510.........520....... ..
Predicted Secondary structure 






















.

..


.

Query SS confidence 










































.





. .
























.

Query Sequence  TQQVNTVTDFWNMVWQENTRVIVMTTKEYERGKEKCARYWPDE. GRSEQF. . GHARIQCVSENSTSDYTLREFLVSW. RD
Query Conservation 
   


 







 

 





   
 

 

 



 
.     
..
   
          



 
 

 .  
Alig confidence  ....






































.





..
























.

Template Conservation  .... 

 


 

       

 
    
     
  


             
 
             
 
 
     
Template Sequence  . . . . NTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTT
Template Known Secondary structure  ....TTTT


S
STT
S


S
SSTTS
GGGT
SSTTT
Template Predicted Secondary structure  ....

























Template SS confidence 















































































   90.........100.........110.........120.........130.........140.........150.........160.....
 
   530.........540.........550.........560.........570.........580.........590.........600.........
Predicted Secondary structure 





























Query SS confidence 















































































Query Sequence  QPARRIFHYHFQVWPDHGVPADPGCVLNFLQDVNTRQSHLAQAGEKPGPICVHCSAGIGRTGTFIVIDMILDQIVRNGLD
Query Conservation    

 
 




 


 


 
   

 

  
              























 

   
 
Alig confidence 


































....








































Template Conservation       
       
 
   
            
  ....         





  
 



 
 

      
      
Template Sequence  QETREILHFHYTTWPDFGVPESPASFLNFLFKVRE. . . . SGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDP
Template Known Secondary structure 





TT


S
....TTTT
TTS


SSSSSSS
G
Template Predicted Secondary structure 












....















Template SS confidence 















































































   166...170.........180.........190.........200 .........210.........220.........230.........240.
 
   610.........620.........630.........640.........650.........660.....
Predicted Secondary structure 














Query SS confidence 























































Query Sequence  TEIDIQRTIQMVRSQRSGLVQTEAQYKFVYYAVQHYIQTLIARKRAEEQSLQVGRE
Query Conservation    


   

 

 

  



 


 


 

  

 

                
Alig confidence 























































Template Conservation    


   
  

 

   
 
  

 


  

                      
Template Sequence  SSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHE
Template Known Secondary structure  GG

TTTSTT
S
STT
SSTT
Template Predicted Secondary structure 













Template SS confidence 























































   242.......250.........260.........270.........280.........290.......
 
Download:Text version FASTA pairwise alignment 3D Model in PDB format

View in Jmol

Send structure to FirstGlance for more viewing options


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions