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Job DescriptionP29349
Confidence100.00%DateTue Jan 22 11:46:53 GMT 2013
Rank3Aligned Residues482
% Identity75%Templatec2shpA_
PDB info PDB header:tyrosine phosphataseChain: A: PDB Molecule:shp-2; PDBTitle: tyrosine phosphatase shp-2
Resolution2.00 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   2.......10.........20.........30.........40.........50.........60.........70.........80.
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Query Sequence  SSRRWFHPTISGIEAEKLLQEQGFDGSFLARLSSSNPGAFTLSVRRGNEVTHIKIQNNGDFFDLYGGEKFATLPELVQYY
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Template Sequence  KSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDLTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYY
Template Known Secondary structure 

STTB
SS



TT
SSSTT
TT
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   2.......10.........20.........30.........40.........50.........60.........70.........80.
 
   82.... ...90.........100.........110.........120.........130.........140.........150.. ...
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Query Sequence  MENGE. LKEKNGQAIELKQPLICAEPTTERWFHGNLSGKEAEKLILERGKNGSFLVRESQSKPGDFVLSVRT. . . . . DDK
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Template Sequence  MEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDNDGKSK
Template Known Secondary structure  T
TT
SBSSSS
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TT
TTB

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   82.......90.........100.........110.........120.........130.........140.........150.........160.
 
   156...160.........170.........180.........190.........200.........210.........220.........230.....
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Query Sequence  VTHVMIRWQDKKYDVGGGESFGTLSELIDHYKRNPMVETCGTVVHLRQPFNATRITAAGINARVEQLVKGGFWEEFESLQ
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Template Sequence  VTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSK. GFWEEFETLQ
Template Known Secondary structure  TTSSSS

BSSS

B
TTS
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S
GGG
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   167..170.........180.........190.........200.........210.........220.........230..... ....240.....
 
   236...240 .........250.........260.........270.........280.........290.........300.........310....
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Query Sequence  QDSRD. TFSRNEGYKQENRLKNRYRNILPYDHTRVKLLDVEHSVAGAEYINANYIRLPTDGDLYNMSSSSESLNSSVPSC
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Template Sequence  QQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLH. . . . . . . DSDYINANIIM. . PKKS. . . . . . . . . . . . . . . . . .
Template Known Secondary structure  GGGGGG



SGGGGGGSSSTT



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   256...260.........270.........280.........290... ......300.... ....
 
   315....320.........330.........340.........350.........360.........370.........380.........390....
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Query Sequence  PACTAAQTQRNCSNCQLQNKTCVQCAVKSAILPYSNCATCSRKSDSLSKHKRSESSASSSPSSGSGSGPGSSGTSGVSSV
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   395....400.........410.........420.........430.........440.........450.........460.........470....
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Query Sequence  NGPGTPTNLTSGTAGCLVGLLKRHSNDSSGAVSISMAEREREREREMFKTYIATQGCLLTQQVNTVTDFWNMVWQENTRV
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . YIATQGCL. . . . QNTVNDFWRMVFQENSRV
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....TTTT

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   327..330.... .....340.........350..
 
   475....480.........490.........500.........510.........520........ .530.........540.........550..
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Query Sequence  IVMTTKEYERGKEKCARYWPDEGRSEQFGHARIQCVSENSTSDYTLREFLVSWR. . DQPARRIFHYHFQVWPDHGVPADP
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Template Sequence  IVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDP
Template Known Secondary structure 
S
STTS



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TT
TT
SSTT



SSS

S
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   353......360.........370.........380.........390.........400.........410.........420.........430..
 
   553......560.........570.........580.........590.........600.........610.........620.........630..
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Query Sequence  GCVLNFLQDVNTRQSHLAQAGEKPGPICVHCSAGIGRTGTFIVIDMILDQIVRNGLDTEIDIQRTIQMVRSQRSGLVQTE
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Template Sequence  GGVLDFLEEVHHKQESIMDA. . . . GPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTE
Template Known Secondary structure  STT
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   433......440.........450.. .......460.........470.........480.........490.........500........
 
   633......640.........
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Query Sequence  AQYKFVYYAVQHYIQTL
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Template Conservation   

 


 

  

   
Template Sequence  AQYRSIYMAVQHYIETL
Template Known Secondary structure  T
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   509510.........520.....
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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