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Job DescriptionP29349
Confidence100.00%DateTue Jan 22 11:46:53 GMT 2013
Rank21Aligned Residues261
% Identity35%Templatec2oc3A_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:tyrosine-protein phosphatase non-receptor type PDBTitle: crystal structure of the catalytic domain of human protein2 tyrosine phosphatase non-receptor type 18
Resolution1.50 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   227..230...... ...240.........250.........260.........270.........280.........290.........300.
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Query Sequence  FWEEFESLQQ. . . . . DSRDTFSRNEGYKQENRLKNRYRNILPYDHTRVKLLDVEHSVAGAEYINANYIRLPTDGDLYNMS
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Template Sequence  LAGEFSDIQACSAAWKADGVCSTVAGSRPENVRKNRYKDVLPYDQTRVILSLLQ. EEGHSDYINGNFIR. . GVDGSLAYI
Template Known Secondary structure  SS


STTTGGG
SSTT



GGG

TTG.GGT

S..
TTSS
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   26...30.........40.........50.........60.........70......... 80.........90... ......100..
 
   302.......310.........320.........330.........340.........350.........360.........370.........380.
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Query Sequence  SSSESLNSSVPSCPACTAAQTQRNCSNCQLQNKTCVQCAVKSAILPYSNCATCSRKSDSLSKHKRSESSASSSPSSGSGS
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Template Sequence  ATQGPLP. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   103......
 
   382.......390.........400.........410.........420.........430.........440.........450.........460.
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Query Sequence  GPGSSGTSGVSSVNGPGTPTNLTSGTAGCLVGLLKRHSNDSSGAVSISMAEREREREREMFKTYIATQGCLLTQQVNTVT
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Template Conservation  ............................................................................ 
  
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . HTLL
Template Known Secondary structure  ............................................................................GG
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   110...
 
   462.......470.........480.........490.........500.........510.........520.........530.........540.
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Query Sequence  DFWNMVWQENTRVIVMTTKEYERGKEKCARYWPDEGRSEQFGHARIQCVSENSTSDYTLREFLVSWRDQPARRIFHYHFQ
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Template Sequence  DFWRLVWEFGVKVILMACREIENGRKRCERYWAQEQEPLQTGLFCITLIKEKWLNEDIMLRTLKVTFQKESRSVYQLQYM
Template Known Secondary structure  TT


S
STT




S
BTTB
TTTTTT
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   114.....120.........130.........140.........150.........160.........170.........180.........190...
 
   542.......550.........560.........570.........580.........590.........600.........610.........620.
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Query Sequence  VWPDHGVPADPGCVLNFLQDVNTRQSHLAQAGEKPGPICVHCSAGIGRTGTFIVIDMILDQIVRNGLDTEIDIQRTIQMV
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Template Sequence  SWPDRGVPSSPDHMLAMVEEARRLQG. . . . . . SGPEPLCVHCSAGCGRTGVLCTVDYVRQLLLTQMIPPDFSLFDVVLKM
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SSS

S
S
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SSSSTT


TT

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   194.....200.........210......... 220.........230.........240.........250.........260.......
 
   622.......630.........640.....
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Query Sequence  RSQRSGLVQTEAQYKFVYYAVQHY
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Template Sequence  RKQRPAAVQTEEQYRFLYHTVAQM
Template Known Secondary structure  TTSTTSS
S
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   268.270.........280.........290.
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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