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Job DescriptionP29349
Confidence100.00%DateTue Jan 22 11:46:53 GMT 2013
Rank8Aligned Residues406
% Identity25%Templatec2nlkA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:protein tyrosine phosphatase, receptor type, g variant PDBTitle: crystal structure of d1 and d2 catalytic domains of human protein2 tyrosine phosphatase gamma (d1+d2 ptprg)
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   210.........220...... ...230.........240 .........250.........260.........270.........280.....
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Query Sequence  ITAAGINARVEQLVKGG. . . FWEEFESLQQDSRD. TFSRNEGYKQENRLKNRYRNILPYDHTRVKLLDVEHSVAGAEYIN
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Template Sequence  IPVKQFVKHIGELYSNNQHGFSEDFEEVQRCTADMNITAEHSNHPENKHKNRYINILAYDHSRVKL. . . . RPLPHSDYIN
Template Known Secondary structure  GGGTTGGG



TTTTSGGGGGG
SSTT



TTT
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TT
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   828.830.........840.........850.........860.........870.........880.........890... ......900...
 
   286...290.........300.........310.........320.........330.........340.........350
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Query Sequence  ANYIRLPTDGDLYNMSSSSESLNSSVPSCPACTAAQTQRNCSNCQLQNKTCVQCAVKSAILPYSN. . . . . . . . . . . . . . .
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Template Sequence  ANYVD. . GYNKAKAYIATQGPLKSTFEDFWRMIWEQNTGIIVMITNLVEKGRRKCDQYWPTENSEEYGNIIVTLKSTKIH
Template Known Secondary structure  ..TT



GGGT


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STT




S
SSSTT
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   909910... ......920.........930.........940.........950.........960.........970.........980......
 
   351........360.........370...... ...380.........390
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . CATCSRKSDSLSKHKRSESSASSSPS. . . . . . . . . . . . . . . . SGSGSGPGSSGTSG
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Template Sequence  ACYTVRRFSIRNTKVKKGQKGNPKGRQNERVVIQYHYTQWPDMGVPEYALPVLTFVRRSSAARMPETGPVLVHCSAGVGR
Template Known Secondary structure  SSTTS



TT
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TT



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S
ST

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   987..990.........1000.........1010.........1020.........1030.........1040.........1050.........1060......
 
   391........400... ......410.........420..
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Query Sequence  VSSVNGPGTPTNL. . . . . . . . . . . . . . . TSGTAGCLVGLLKRHSNDS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  TGTYIVIDSMLQQIKDKSTVNVLGFLKHIRTQRNYLVQTEEQYIFIHDALLEAILGKETEVSSNQLHSYVNSILIPTRLE
Template Known Secondary structure  S
TTTSTTSS

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GGGT


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   1067..1070.........1080.........1090.........1100.........1110.........1120.........1130.........1140......
 
   423......430.........440.........450.........460.........470
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . SGAVSISMAEREREREREMFKTYIATQGCLLTQQVNTVTDFWNMVWQE
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Template Sequence  KQFKLVTQCFSAQKECNKEKNRNSSVVPSERARVGLAPDYINASYIMGYYRSNEFIITQHPL. . . . PHTTKDFWRMIWDH
Template Known Secondary structure  S



TTSSS
TTS
S
TTS


STTB







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SS
TTS


....GGG
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   1152.......1160.........1170.........1180.........1190.........1200.........1210... ......1220.......
 
   471........480.........490.........500.........510.... .....520....... ..530.........540....
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Query Sequence  NTRVIVMTTKEYERGKEKCARYWPDEGRSEQFGHARIQCVSENS. . . . . TSDYTLREFLVSW. RDQPARRIFHYHFQVWP
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Template Sequence  NAQIIVML. . . . . . . . . . PFVYWPSREESMNCEAFTVTLISKDRLCLSNEEQIIIHDFILEATQDDYVLEVRHFQCPKWP
Template Known Secondary structure  T


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   1242....... 1250.........1260.........1270.........1280.........1290.........1300.........1310.
 
   545....550.........560.........570.........580.........590.........600.........610.........620....
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Query Sequence  DHGVPADPGCVLNFLQDVNTRQSHLAQAGEKPGPICVHCSAGIGRTGTFIVIDMILDQIVRNGLDTEIDIQRTIQMVRSQ
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Template Sequence  NPDAP. . ISSTFELINVIKEEAL. . . . . . TRDGPTIVHDEYGAVSAGMLCALTTLSQQLENENA. . . VDVFQVAKMINLM
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TTS
..GGGT......T

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   1321.... ....1330.........1340. ........1350.........1360.........1370...... ...1380.........
 
   625....630.........640......
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Query Sequence  RSGLVQTEAQYKFVYYAVQHYI
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Template Sequence  RPGVFTDIEQYQFIYKAMLSLV
Template Known Secondary structure  STTSS
STT
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   1390.........1400.........1410.
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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