|   |   |
220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
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|  |  |  |  |
|
|  |  |
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|  |  |  |  |
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|  |  |  |  |  |  |
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|  |
| Query SS confidence |   |
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| Query Sequence |   |
E | Q | L | V | K | G | G | F | W | E | E | F | E | S | L | Q | Q | D | S | R | D | T | F | S | R | N | E | G | Y | K | Q | E | N | R | L | K | N | R | Y | R | N | I | L | P | Y | D | H | T | R | V | K | L | L | D | V | E | H | S | V | A | G | A | E | Y | I | N | A | N | Y | I | R | L | P | T | D | G | D | L | Y | N |
| Query Conservation |   |
  |   |   |   |   |   |
|
|   |
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|   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
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|   |
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|   |
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|   |   |
|   |   |   |   |
|   |
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|   |
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|   |   |   |
|
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| Alig confidence |   |
|
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| . |
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| . | . |
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| . | . |
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| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |   |   |
|   |   |   |
|   |   |
|
|   |
|   |   |   |   |   | . | . |   |   |   |
|
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|   |
|   | . | . |   |   |   |   |   |   |   |
| Template Sequence |   |
E | E | E | I | R | I | R | S | R | E | E | F | N | S | L | P | S | G | H | I | Q | G | . |
T | F | E | L | A | N | K | E | E | N | R | E | K | N | R | Y | P | N | I | L | P | N | D | H | S | R | V | I | L | S | Q | L | G | I | . |
. |
P | C | S | D | Y | I | N | A | S | Y | I | D | . |
. |
G | Y | K | E | K | N | K |
| Template Known Secondary structure |   |
 |  |  |  |  |  | T |
|
| T | T | G | G | G | S |
|
| T | T | S | S |
| . |
|
| T | T | T | T |
| G | G | G | G | G | G |
| S | S | T | T | S |
|
|
| S | S | S |  |  |  |
|
|
|
|
|
| . | . | T | T | T | T |  |  |  |  |  |  |  |  | . | . |  | T | T |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
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|
| . |
|  |  |  |  |
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|  |  |  |  |
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| . | . |
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|  |  |  |  |  |  |
|
| . | . |
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|  |
| Template SS confidence |   |
|
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|   |   |
121 | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | |
. | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | |
|
. | . | . | 180 | . | . | . | . | . | . | . | . | |
|
. | 190 | . | . | . | . | . |
|   |
|   |   |
300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | |
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|
. | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |
|
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|  |  |  |  |
|
|  |  |  |  |
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|  |  |  |  |
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| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
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|
| Query SS confidence |   |
|
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| . |
. |
. |
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. |
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| Query Sequence |   |
M | S | S | S | S | E | S | L | N | S | S | V | P | S | C | P | A | C | T | A | A | Q | T | Q | R | N | C | S | N | C | Q | L | Q | N | K | T | C | V | Q | C | A | V | K | S | A | I | L | P | Y | S | N | . |
. |
. |
. |
. |
. |
. |
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. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
C | A | T | C |
| Query Conservation |   |
|
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|   |   |
|
|   |
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|   |   |   |   |
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|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |
| Alig confidence |   |
|
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| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
| Template Conservation |   |
  |
|   |
|
|   |
|   |   |   |
|   |   |
|
|
|   |
|
|   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |
|   |   |   |   |
|
|   |   |
|
|
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |
| Template Sequence |   |
F | I | A | A | Q | G | P | K | Q | E | T | V | N | D | F | W | R | M | V | W | E | Q | K | S | A | T | I | V | M | L | T | N | L | K | E | R | K | E | E | K | C | H | Q | Y | W | P | D | Q | G | C | W | T | Y | G | N | I | R | V | C | V | E | D | C | V | V | L | V | D | Y | T | I | R | K | F | C | I | Q | P | K | A |
| Template Known Secondary structure |   |
 |  |  |  |
|
|
|
| G | G | G |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |
| S |
| S |  |  | T | T |  |  |
| S |
|
|
| S |
| S | S | S |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  | B |
|
|
|
| Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
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|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
| Template SS confidence |   |
|
|
|
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|
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|   |   |
204 | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . |
|   |
|   |   |
355 | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | |
|
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|
. | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | |
|
|
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|
|
| Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
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|
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|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
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|
|  |  |
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Query SS confidence |   |
|
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| . |
. |
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| . |
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. |
. |
| Query Sequence |   |
S | R | K | S | D | S | L | S | K | H | K | R | S | E | S | S | A | S | S | S | P | S | . |
. |
. |
. |
. |
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. |
. |
S | G | S | G | S | G | P | G | S | S | G | T | S | G | V | S | S | V | N | G | P | G | T | P | T | N | L | . |
. |
. |
. |
. |
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. |
. |
. |
| Query Conservation |   |
  |
|   |
|   |
|   |
|
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|   |
|
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|   |
|
|
|   |   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|   |   |
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|   |
|   |   |
|   |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Alig confidence |   |
|
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| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
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| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Template Conservation |   |
  |
|   |
|   |
|   |   |
|   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
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|   |
|
|
|   |
|   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |   |   |
|   |   |
| Template Sequence |   |
P | R | L | V | S | Q | L | H | F | T | S | W | P | D | F | G | V | P | F | T | P | I | G | M | L | K | F | L | K | K | V | K | T | L | N | P | V | H | A | G | P | I | V | V | H | C | S | A | G | V | G | R | T | G | T | F | I | V | I | D | A | M | M | A | M | M | H | A | E | Q | K | V | D | V | F | E | F | V | S | R |
| Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |
|
|
|
| S | S | S |
|
| S |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
| T | T |
|
|
|  |  |  |  |
| S | S | S | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |  |  |
|  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |
|
|
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|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
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|  |  |  |  |  |
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|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
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|  |  |  |  |  |  |  |
| Template SS confidence |   |
|
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|   |   |
290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . |
|   |
|   |   |
404 | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | |
|
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| Predicted Secondary structure |   |
 |  |  |
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Query SS confidence |   |
|
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| . |
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| Query Sequence |   |
T | S | G | T | A | G | C | L | V | G | L | L | K | R | H | S | N | D | S | . |
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| Query Conservation |   |
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|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Alig confidence |   |
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| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Template Conservation |   |
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|   |   |
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|   |
|   |
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|   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
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|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
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| Template Sequence |   |
I | R | N | Q | R | P | Q | M | V | Q | T | D | M | Q | Y | T | F | I | Y | Q | A | L | L | E | Y | Y | L | Y | G | D | T | E | L | D | V | S | S | G | L | E | E | E | F | R | K | L | T | N | V | R | I | M | K | E | N | M | R | T | G | N | L | P | A | N | M | K | K | A | R | V | I | Q | I | I | P | Y | D | F | N | R |
| Template Known Secondary structure |   |
 |  | T | T | S | T | T |
| S |
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|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
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|  |  | T | T |
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|  |  |  |  |  |  |  |  |  | T | S |
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| S | T | T |
|  |  |  |  | S |  |  |  |  | T | T |
| S | S | T | T | S |
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| S | S | S |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
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| Template SS confidence |   |
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|   |   |
370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . |
|   |
|   |   |
|
423 | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . |
| Predicted Secondary structure |   |
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| Query SS confidence |   |
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| Query Sequence |   |
. |
S | G | A | V | S | I | S | M | A | E | R | E | R | E | R | E | R | E | M | F | K | T | Y | I | A | T | Q | G | C | L | L | T | Q | Q | V | N | T | V | T | D | F | W | N | M | V | W | Q | E | N | T | R | V | I | V | M | T | T | K | E | Y | E | R | G | K | E | K | C | A | R | Y | W | P | D | E | G | R | S | E | Q |
| Query Conservation |   |
. |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
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| Alig confidence |   |
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| . |
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| Template Conservation |   |
|   |
|   |   |   |   |
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|   |   |   |   |   |   |
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|   |
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| . | . | . | . |   |   |
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|   |   |   |   |
|   |   |   |   |
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|   |
|   |   |   | . |   |   |   |
| Template Sequence |   |
V | I | L | S | M | Y | T | D | Y | I | N | A | S | F | I | D | G | Y | R | Q | K | D | Y | F | I | A | T | Q | G | P | L | . |
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A | H | T | V | E | D | F | W | R | M | I | W | E | W | K | S | H | T | I | V | M | L | T | E | V | Q | E | R | E | Q | D | K | C | Y | Q | Y | W | P | T | E | G | . |
S | V | T |
| Template Known Secondary structure |   |
 |  |
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| T | T |  |  |  |  |  |  |  |
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| S | S | S | T | T |
|  |  |  |  |
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| . | . | . | . | T | T | T |  |  |  |  |  |  |  |  |  |  | T | T |
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|  |  |  |  |
| S |
| S |  |  | T | T |  |  |
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| S |
| S | S | S | . |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |
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|  |  |  |  |  |  |
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|  |  |  |  |  |
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| . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
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| . |
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| Template SS confidence |   |
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|   |   |
468 | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | |
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. | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | |
540 | . | . |
|   |
|   |   |
502 | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
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|  |  |  |  |  |  |  |  |  |  |
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| Query SS confidence |   |
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| Query Sequence |   |
F | G | H | A | R | I | Q | C | V | S | E | N | S | T | S | D | Y | T | L | R | E | F | L | V | S | W | R | D | Q | P | A | R | R | I | F | H | Y | H | F | Q | V | W | P | D | H | G | V | P | A | D | P | G | C | V | L | N | F | L | Q | D | V | N | T | R | Q | S | H | L | A | Q | A | G | E | K | P | G | P | I | C | V |
| Query Conservation |   |
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|   |   |   |
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|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
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| Alig confidence |   |
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| . | . | . | . | . |
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| Template Conservation |   |
  |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
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|
|   |   |   |
|   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |
|
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| Template Sequence |   |
H | G | E | I | T | I | E | I | K | N | D | T | L | S | E | A | I | S | I | R | D | F | L | V | T | L | N | G | E | Q | V | R | V | V | R | Q | F | H | F | H | G | W | P | E | I | G | I | P | A | E | G | K | G | M | I | D | L | I | A | A | V | Q | K | Q | Q | Q | Q | . |
. |
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T | G | N | H | P | I | T | V |
| Template Known Secondary structure |   |
 | T | T |  |  |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  |  |  |
|
| T | T |  |  |  |  |  |  |  |  |  |
|
| S |
| S | S | S |
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| S |
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|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | S | T | T |
|
|  |  |  |
| Template Predicted Secondary structure |   |
 |
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|  |  |  |  |  |  |  |  |  |  |
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|  |  |  |  |  |  |  |  |  |  |
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|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . |
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| Template SS confidence |   |
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|   |   |
548 | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | |
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. | . | . | . | . | 620 | . | . |
|   |
|   |   |
582 | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |
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|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
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|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
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| Query Sequence |   |
H | C | S | A | G | I | G | R | T | G | T | F | I | V | I | D | M | I | L | D | Q | I | V | R | N | G | L | D | T | E | I | D | I | Q | R | T | I | Q | M | V | R | S | Q | R | S | G | L | V | Q | T | E | A | Q | Y | K | F | V | Y | Y | A | V | Q | H | Y | I | Q |
| Query Conservation |   |
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| Alig confidence |   |
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| Template Conservation |   |
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|   |   |   |   |   |   |
|   |   |   |   |   | . | . | . |
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|   |   |   |
|   |
|   |   |
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|   |
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|   |   |
|   |   |
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|   |
| Template Sequence |   |
H | C | S | A | G | A | G | R | T | G | T | F | I | A | L | S | N | I | L | E | R | V | K | A | E | G | L | . |
. |
. |
L | D | V | F | Q | A | V | K | S | L | R | L | Q | R | P | H | M | V | Q | T | L | E | Q | Y | E | F | C | Y | K | V | V | Q | D | F | I | D |
| Template Known Secondary structure |   |
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| S | S | S | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |  | . | . | . |  |
|  |  |  |  |  |  |  |  |  | T | T | S | T | T | S | S |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
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| Template Predicted Secondary structure |   |
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| Template SS confidence |   |
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|   |   |
629 | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | |
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. | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . |
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