Phyre 2 alignment of P29349 with c2h04A

Job Description P29349
Confidence 100.00% Date Tue Jan 22 11:46:53 GMT 2013

Rank 33 Aligned Residues 270

% Identity 43% Template c2h04A_

PDB info PDB header:hydrolase Chain: A: PDB Molecule:protein tyrosine phosphatase, receptor type, b,; PDBTitle: structural studies of protein tyrosine phosphatase beta2 catalytic domain in complex with inhibitors

Resolution 2.30 Å

	Insertion relative to template
	Deletion relative to template
	Catalytic residue from the CSA

Detailed help on interpreting your alignment

	210	.	.	.	.	.	.	.	.	.	220	.	.	.				.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.
Predicted Secondary structure															.	.	.
Query SS confidence															.	.	.
Query Sequence	I	T	A	A	G	I	N	A	R	V	E	Q	L	V	.	.	.	K	G	G	F	W	E	E	F	E	S	L	Q	Q	D	S	R	D	T	F	S	R	N	E	G	Y	K	Q	E	N	R	L	K	N	R	Y	R	N	I	L	P	Y	D	H	T	R	V	K	L	L	D	V	E	H	S	V	A	G	A	E	Y	I	N	A
Query Conservation															.	.	.
Alig confidence															.	.	.																			.																														.	.	.	.	.	.	.
Template Conservation																																				.																														.	.	.	.	.	.	.
Template Sequence	I	K	I	N	Q	F	E	G	H	F	M	K	L	Q	A	D	S	N	Y	L	L	S	K	E	Y	E	E	L	K	D	V	G	R	N	Q	.	S	C	D	I	A	L	L	P	E	N	R	G	K	N	R	Y	N	N	I	L	P	Y	D	A	T	R	V	K	L	.	.	.	.	.	.	.	S	N	S	D	Y	I	N	A
Template Known Secondary structure			G	G	G									T														T	T	T	T	T	T	T	S	.			T	T	T	T	S	G	G	G	G	G	G		S	S	T	T			B		T	T	T					.	.	.	.	.	.	.
Template Predicted Secondary structure																																				.																														.	.	.	.	.	.	.
Template SS confidence
	1683	.	.	.	.	.	.	1690	.	.	.	.	.	.	.	.	.	1700	.	.	.	.	.	.	.	.	.	1710	.	.	.	.	.	.	.		.	.	1720	.	.	.	.	.	.	.	.	.	1730	.	.	.	.	.	.	.	.	.	1740	.	.	.	.	.	.								.	.	.	1750	.	.	.	.

	287	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence	N	Y	I	R	L	P	T	D	G	D	L	Y	N	M	S	S	S	S	E	S	L	N	S	S	V	P	S	C	P	A	C	T	A	A	Q	T	Q	R	N	C	S	N	C	Q	L	Q	N	K	T	C	V	Q	C	A	V	K	S	A	I	L	P	Y	S	N	C	A	T	C	S	R	K	S	D	S	L	S	K	H	K	R
Query Conservation
Alig confidence					.	.																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation					.	.																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence	S	Y	I	P	.	.	G	N	N	F	R	R	E	Y	I	V	T	Q	G	P	L	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure					.	.		S	S		T	T										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure					.	.																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
	1761	.	.	.			.	.	.	.	.	1770	.	.	.	.	.	.	.	.	.

	367	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence	S	E	S	S	A	S	S	S	P	S	S	G	S	G	S	G	P	G	S	S	G	T	S	G	V	S	S	V	N	G	P	G	T	P	T	N	L	T	S	G	T	A	G	C	L	V	G	L	L	K	R	H	S	N	D	S	S	G	A	V	S	I	S	M	A	E	R	E	R	E	R	E	R	E	M	F	K	T	Y	I
Query Conservation
Template Conservation	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence


	447	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence	A	T	Q	G	C	L	L	T	Q	Q	V	N	T	V	T	D	F	W	N	M	V	W	Q	E	N	T	R	V	I	V	M	T	T	K	E	Y	E	R	G	K	E	K	C	A	R	Y	W	P	D	E	G	R	S	E	Q	F	G	H	A	R	I	Q	C	V	S	E	N	S	T	S	D	Y	T	L	R	E	F	L	V	S
Query Conservation
Alig confidence	.	.	.	.	.	.	.	.	.	.
Template Conservation	.	.	.	.	.	.	.	.	.	.
Template Sequence	.	.	.	.	.	.	.	.	.	.	P	G	T	K	D	D	F	W	K	M	V	W	E	Q	N	V	H	N	I	V	M	V	T	Q	C	V	E	K	G	R	V	K	C	D	H	Y	W	P	A	D	Q	D	S	L	Y	Y	G	D	L	I	L	Q	M	L	S	E	S	V	L	P	E	W	T	I	R	E	F	K	I	C
Template Known Secondary structure	.	.	.	.	.	.	.	.	.	.	T	T	T											T	T								S		S			T	T				S				S		S	S	S	S					T	T												S	S
Template Predicted Secondary structure	.	.	.	.	.	.	.	.	.	.
Template SS confidence
											1780	.	.	.	.	.	.	.	.	.	1790	.	.	.	.	.	.	.	.	.	1800	.	.	.	.	.	.	.	.	.	1810	.	.	.	.	.	.	.	.	.	1820	.	.	.	.	.	.	.	.	.	1830	.	.	.	.	.	.	.	.	.	1840	.	.	.	.	.	.	.	.	.

	527	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence	W	R	D	Q	P	A	R	R	I	F	H	Y	H	F	Q	V	W	P	D	H	G	V	P	A	D	P	G	C	V	L	N	F	L	Q	D	V	N	T	R	Q	S	H	L	A	Q	A	G	E	K	P	G	P	I	C	V	H	C	S	A	G	I	G	R	T	G	T	F	I	V	I	D	M	I	L	D	Q	I	V	R	N
Query Conservation
Alig confidence	.	.	.																																								.	.	.	.
Template Conservation	.	.	.																																								.	.	.	.
Template Sequence	.	.	.	G	E	H	R	L	I	R	H	F	H	Y	T	V	W	P	D	H	G	V	P	E	T	T	Q	S	L	I	Q	F	V	R	T	V	R	D	Y	I	N	R	.	.	.	.	S	P	G	A	G	P	T	V	V	H	C	S	A	G	V	G	R	T	G	T	F	I	A	L	D	R	I	L	Q	Q	L	D	S	K
Template Known Secondary structure	.	.	.																T	T	S			S																		T	.	.	.	.	S	T	T									S	S	S	S																T	T	T
Template Predicted Secondary structure	.	.	.																																								.	.	.	.
Template SS confidence
				1850	.	.	.	.	.	.	.	.	.	1860	.	.	.	.	.	.	.	.	.	1870	.	.	.	.	.	.	.	.	.	1880	.	.	.	.	.	.	.	.					.	1890	.	.	.	.	.	.	.	.	.	1900	.	.	.	.	.	.	.	.	.	1910	.	.	.	.	.	.	.	.	.	1920	.	.

	607	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence	G	L	D	T	E	I	D	I	Q	R	T	I	Q	M	V	R	S	Q	R	S	G	L	V	Q	T	E	A	Q	Y	K	F	V	Y	Y	A	V	Q	H	Y	I	Q	T
Query Conservation
Alig confidence			.	.	.
Template Conservation			.	.	.
Template Sequence	D	S	.	.	.	V	D	I	Y	G	A	V	H	D	L	R	L	H	R	V	H	M	V	Q	T	E	C	Q	Y	V	Y	L	H	Q	C	V	R	D	V	L	R	A
Template Known Secondary structure	S		.	.	.														B	T	T	S	S		S
Template Predicted Secondary structure			.	.	.
Template SS confidence
	1928	.				1930	.	.	.	.	.	.	.	.	.	1940	.	.	.	.	.	.	.	.	.	1950	.	.	.	.	.	.	.	.	.	1960	.	.	.	.	.	.

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No model constructed - rank, confidence too low

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server

Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]

© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys
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