Return to main results Retrieve Phyre Job Id

Job DescriptionP29349
Confidence100.00%DateTue Jan 22 11:46:53 GMT 2013
Rank2Aligned Residues488
% Identity55%Templatec2b3oA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type PDBTitle: crystal structure of human tyrosine phosphatase shp-1
Resolution2.80 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   5....10.........20.........30.........40.........50.........60.........70.........80....
Predicted Secondary structure 

































Query SS confidence 















































































Query Sequence  RWFHPTISGIEAEKLLQEQGFDGSFLARLSSSNPGAFTLSVRRGNEVTHIKIQNNGDFFDLYGGEKFATLPELVQYYMEN
Query Conservation   



 


 


 

   
 








    
 
 

      
 
  
   

 
 
  
  
 

 


 

   
Alig confidence 















































































Template Conservation   



 
 
  

 

   
 

 



 
    
   

      
 
  
              
 

 


  
   
Template Sequence  RWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDFYDLYGGEKFATLTELVEYYTQQ
Template Known Secondary structure  TTB
SS



TT
SSSSSTT
SSS
TTS
S
TT
Template Predicted Secondary structure 


































Template SS confidence 















































































   3......10.........20.........30.........40.........50.........60.........70.........80..
 
   85. ...90.........100.........110.........120.........130.........140.........150.. ......
Predicted Secondary structure 

.







































.....

Query SS confidence 

.

































































. . . . .





Query Sequence  GE. LKEKNGQAIELKQPLICAEPTTERWFHGNLSGKEAEKLILERGKNGSFLVRESQSKPGDFVLSVRT. . . . . DDKVTH
Query Conservation    . 
  
     
  

    
    



 
 
 


  
     






 
    
 



   .....   
 
Alig confidence 

.

































































.....





Template Conservation     
         
  
          



 
 
 


 

     

 



 
 
  
 
 

           
 
Template Sequence  QGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKSPLRVTH
Template Known Secondary structure 
S
B

SSS

B







GGG
TTB
TT



TT
SSSTT



Template Predicted Secondary structure 



















































Template SS confidence 















































































   83......90.........100.........110.........120.........130.........140.........150.........160..
 
   159160.........170.........180.........190.........200.........210.........220.........230...... .
Predicted Secondary structure 

































.
Query SS confidence 













































































.
Query Sequence  VMIRWQDKKYDVGGGESFGTLSELIDHYKRNPMVETCGTVVHLRQPFNATRITAAGINARVEQLVKGGFWEEFESLQQ. D
Query Conservation    
      
 
  
  
 

  

 

   



       
          
             

 



 
  . 
Alig confidence 



























































........









.
Template Conservation    
        
     
 

  

  
   

    
    
  
             
........
  

  
    
Template Sequence  IKVMCEGGRYTVGGLETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENR. . . . . . . . FWEEFESLQKQE
Template Known Secondary structure  B

TTSBBSSSS

BSS

SSS











GGGT

........
TTT
Template Predicted Secondary structure 
































........


Template SS confidence 















































































   167..170.........180.........190.........200.........210.........220...... ...230........
 
   238.240.........250.........260.........270.........280.........290... ......300.........310..
Predicted Secondary structure 







































.....











Query SS confidence 























































. . . . .


















Query Sequence  SRDTFSRNEGYKQENRLKNRYRNILPYDHTRVKLLDVEHSVAGAEYINANYIRLPT. . . . . DGDLYNMSSSSESLNSSVP
Query Conservation       
       


 



 











  
    
 









 

.....
   









  

 
Alig confidence 




















































..
.....













.....
Template Conservation                
  



  




 


 
         








 ..
           




 

.....
Template Sequence  VKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSDYINANYIK. . NQLLGPDENAKTYIASQGCL. . . . .
Template Known Secondary structure  TTT




GGGSTTGGGG
SSTT



TTTB


SS

TTSSS
S

S
..
TTS
TTS







.....
Template Predicted Secondary structure 

































..














.....
Template SS confidence 















































































   256...260.........270.........280.........290.........300........ .310.........320........
 
   313......320.........330.........340.........350.........360.........370.........380.........390..
Predicted Secondary structure 






























































Query SS confidence 















































































Query Sequence  SCPACTAAQTQRNCSNCQLQNKTCVQCAVKSAILPYSNCATCSRKSDSLSKHKRSESSASSSPSSGSGSGPGSSGTSGVS
Query Conservation 








    




   
                     
 
 
 


 


 


  
   
  










Template Conservation  ................................................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ................................................................................
Template Predicted Secondary structure  ................................................................................
Template SS confidence 















































































  
 
   393......400.........410.........420.........430.........440.........450.........460.........470..
Predicted Secondary structure 






















































Query SS confidence 















































































Query Sequence  SVNGPGTPTNLTSGTAGCLVGLLKRHSNDSSGAVSISMAEREREREREMFKTYIATQGCLLTQQVNTVTDFWNMVWQENT
Query Conservation 
 
  
  
        
 

   
       
                 
 







 
   


 







 

Alig confidence  ................................................................















Template Conservation  ................................................................  

 


 



   
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . EATVNDFWQMAWQENS
Template Known Secondary structure  ................................................................TTTT
Template Predicted Secondary structure  ................................................................


Template SS confidence 















































































   329330.........340....
 
   473......480.........490.........500.........510.........520....... ..530.........540.........550
Predicted Secondary structure 


















..













Query SS confidence 






















































. .






















Query Sequence  RVIVMTTKEYERGKEKCARYWPDEGRSEQFGHARIQCVSENSTSDYTLREFLVSW. . RDQPARRIFHYHFQVWPDHGVPA
Query Conservation   





   
 

 

 



 
     

   
          



 
 

 ..    

 
 




 


 


 
Alig confidence 






















































..






















Template Conservation    




   
    

  


        
   
             
 
 
         
 
 
  
  


 


 
Template Sequence  RVIVMTTREVEKGRNKCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSWPDHGVPS
Template Known Secondary structure 

S
STT




S

TT

SS

SS
GGGTT





SSS

S
Template Predicted Secondary structure 







































Template SS confidence 















































































   345....350.........360.........370.........380.........390.........400.........410.........420....
 
   551........560.........570.........580.........590.........600.........610.........620.........630
Predicted Secondary structure 

























Query SS confidence 















































































Query Sequence  DPGCVLNFLQDVNTRQSHLAQAGEKPGPICVHCSAGIGRTGTFIVIDMILDQIVRNGLDTEIDIQRTIQMVRSQRSGLVQ
Query Conservation 
   

 

  
              























 

   
 
  


   

 

 

  


Alig confidence 





















....





















































Template Conservation       
 

  
          ....

















 

 

  
        


   
  

 

  


Template Sequence  EPGGVLSFLDQINQRQESLPHA. . . . GPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQ
Template Known Secondary structure  SSSTT
....


SSSSSS
TTS


TTTSTTSS
Template Predicted Secondary structure 




....




















Template SS confidence 















































































   425....430.........440...... ...450.........460.........470.........480.........490.........500
 
   631........640.........650.....
Predicted Secondary structure 

Query SS confidence 
























Query Sequence  TEAQYKFVYYAVQHYIQTLIARKRA
Query Conservation 
 


 


 

  

 

      
Alig confidence 
























Template Conservation 
  

 


  
  

         
Template Sequence  TEAQYKFIYVAIAQFIETTKKKLEV
Template Known Secondary structure  ST
S


Template Predicted Secondary structure 

Template SS confidence 
























   501........510.........520.....
 
Download:Text version FASTA pairwise alignment 3D Model in PDB format

View in Jmol

Send structure to FirstGlance for more viewing options


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions